Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease

targetTB: A target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis

(2012) Karthik Raman et al.   BMC Systems Biology

Increased Glycolytic ATP Synthesis Is Associated with Tafenoquine Resistance inLeishmania major

(2011) José Ignacio Manzano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Differential Effects of Paromomycin on Ribosomes ofLeishmania mexicanaand Mammalian Cells

(2010) Marisa M. Fernández et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Blueprint for antimicrobial hit discovery targeting metabolic networks

(2010) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antileishmanial High-Throughput Drug Screening Reveals Drug Candidates with New Scaffolds

(2010) Jair L. Siqueira-Neto et al.   PLoS Neglected Tropical Diseases

Mass Drug Administration and Integrated Control for the World's High-Prevalence Neglected Tropical Diseases

(2009) PJ Hotez   CLINICAL PHARMACOLOGY & THERAPEUTICS

Molecular Basis of Antimony Treatment in Leishmaniasis†

(2009) Paola Baiocco et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rescuing the bottom billion through control of neglected tropical diseases

(2009) Peter J Hotez et al.   LANCET

Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base

(2009) Olivier Bouchaud et al.   MALARIA JOURNAL

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen

(2009) Elizabeth R. Sharlow et al.   PLoS Neglected Tropical Diseases

Rapid fluorescent assay for screening drugs on Leishmania amastigotes

(2008) Orly Shimony et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Genomic-scale prioritization of drug targets: the TDR Targets database

(2008) Fernán Agüero et al.   NATURE REVIEWS DRUG DISCOVERY

A Global Fund to Fight Neglected Tropical Diseases: Is the G8 Hokkaido Toyako 2008 Summit Ready?

(2008) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases