Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis

Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis

(2014) Reiji Higashiyama et al.   Modern Rheumatology

Class I Histone Deacetylase Inhibition Modulates Metalloproteinase Expression and Blocks Cytokine-Induced Cartilage Degradation

(2013) Kirsty L. Culley et al.   ARTHRITIS AND RHEUMATISM

Histone Deacetylase 3 Suppression Increases PH Domain and Leucine-rich Repeat Phosphatase (Phlpp)1 Expression in Chondrocytes to Suppress Akt Signaling and Matrix Secretion

(2013) Elizabeth W. Bradley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs

(2012) M.J. Barter et al.   OSTEOARTHRITIS AND CARTILAGE

Valproic Acid Suppresses Interleukin-1ß-induced Microsomal Prostaglandin E2 Synthase-1 Expression in Chondrocytes Through Upregulation of NAB1

(2011) NADIA ZAYED et al.   JOURNAL OF RHEUMATOLOGY

Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis

(2010) Wei-Ping Chen et al.   MOLECULAR BIOLOGY REPORTS

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytes

(2009) Sohee Hong et al.   FASEB JOURNAL

Inhibition of histone deacetylases antagonized FGF2 and IL-1β effects on MMP expression in human articular chondrocytes

(2009) Xibin Wang et al.   GROWTH FACTORS

Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

(2008) Matthew J. Bottomley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

(2008) Anja Schuetz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Osteoarthritis Development by Wnt–β-catenin Signaling Through the Endochondral Ossification Process

(2008) Hiroshi Kawaguchi   JOURNAL OF BONE AND MINERAL RESEARCH

Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

(2008) Y. Nasu et al.   OSTEOARTHRITIS AND CARTILAGE

Histone deacetylase inhibitors suppress interleukin-1β-induced nitric oxide and prostaglandin E2 production in human chondrocytes

(2008) N. Chabane et al.   OSTEOARTHRITIS AND CARTILAGE