Histone Deacetylase 3 Suppression Increases PH Domain and Leucine-rich Repeat Phosphatase (Phlpp)1 Expression in Chondrocytes to Suppress Akt Signaling and Matrix Secretion

Histone deacetylase 3 is required for maintenance of bone mass during aging

(2012) Meghan E. McGee-Lawrence et al.   BONE

Hdac-Mediated Control of Endochondral and Intramembranous Ossification

(2012) Jennifer J. Westendorf et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth

(2011) David J. Mulholland et al.   CANCER CELL

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

(2011) Brett S. Carver et al.   CANCER CELL

FOXO1 Inhibits Runx2 Transcriptional Activity and Prostate Cancer Cell Migration and Invasion

(2011) H. Zhang et al.   CANCER RESEARCH

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

(2011) D. Ikegami et al.   DEVELOPMENT

Diet-induced Lethality Due to Deletion of theHdac3Gene in Heart and Skeletal Muscle

(2011) Zheng Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: PHLPP Regulates the Development, Function, and Molecular Signaling Pathways of Regulatory T Cells

(2011) S. J. Patterson et al.   JOURNAL OF IMMUNOLOGY

Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension

(2011) Douglas D. Lemon et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions

(2010) Atsushi Fukai et al.   ARTHRITIS AND RHEUMATISM

Zfp521 Is a Target Gene and Key Effector of Parathyroid Hormone-Related Peptide Signaling in Growth Plate Chondrocytes

(2010) Diego Correa et al.   DEVELOPMENTAL CELL

Histone deacetylases in skeletal development and bone mass maintenance

(2010) Meghan E. McGee-Lawrence et al.   GENE

Identification of folding preferences of cleavage junctions of HIV-1 precursor proteins for regulation of cleavability

(2010) Hirotaka Ode et al.   JOURNAL OF MOLECULAR MODELING

Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis

(2010) Wei-Ping Chen et al.   MOLECULAR BIOLOGY REPORTS

WNT5A Regulates Chondrocyte Differentiation through Differential Use of the CaN/NFAT and IKK/NF-κB Pathways

(2010) Elizabeth W. Bradley et al.   MOLECULAR ENDOCRINOLOGY

Histone Deacetylase 3 Depletion in Osteo/Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat

(2010) David F. Razidlo et al.   PLoS One

Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock

(2010) S. Masubuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2

(2009) M. Gupta et al.   BLOOD

Akt regulates skeletal development through GSK3, mTOR, and FoxOs

(2009) Satoshi Rokutanda et al.   DEVELOPMENTAL BIOLOGY

mTOR signaling contributes to chondrocyte differentiation

(2008) Chanika Phornphutkul et al.   DEVELOPMENTAL DYNAMICS

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

(2008) Sarah K Knutson et al.   EMBO JOURNAL

Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

(2008) Rusty L. Montgomery et al.   JOURNAL OF CLINICAL INVESTIGATION

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

(2008) Srividya Bhaskara et al.   MOLECULAR CELL

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis

(2008) J Liu et al.   ONCOGENE

Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

(2008) Y. Nasu et al.   OSTEOARTHRITIS AND CARTILAGE

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis

(2008) M. Martin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA