Article
Microbiology
Yan Lin, Yankun Liu, Yuyu Zhang, Wenyuan Yuan, Dongyang Wang, Weiyun Zhu
Summary: A virulent bacteriophage, S19cd, was isolated from pig gut and can infect both non-pathogenic Escherichia coli and pathogenic Salmonella enterica serovar Choleraesuis. S19cd exhibits strong lytic ability and can inhibit the growth of these bacteria. Mice pre-treated with S19cd showed protection against the pathogenic strain. S19cd has heat resistance and pH tolerance, and belongs to the Felixounavirus genus without virulence or drug-resistance-related genes. Metagenomic analysis suggests that S19cd-like phages are widespread in Chinese pig gut.
VETERINARY MICROBIOLOGY
(2023)
Article
Microbiology
Jialiang Xu, Jia Li, Yi Yan, Pengjun Han, Yigang Tong, Xu Li
Summary: A lytic phage SW16-7 was isolated from medical sewage, showing high infectivity against Salmonella enterica serovar Weltevreden and other strains. In vitro inhibition assays demonstrated its effective antibacterial effect for up to 12 h. The phage's genome lacks virulence factors and antibiotic resistance genes, suggesting its potential as a biocontrol agent against S. Weltevreden.
Article
Microbiology
Yu-feng Qiu, Reshma B. Nambiar, Xue-bin Xu, Shun-tai Weng, Hang Pan, Kui-cheng Zheng, Min Yue
Summary: Non-typhoidal Salmonella (NTS) is a common cause of gastroenteritis, with the invasive infection caused by an infrequently reported serovar Telelkebir strain FJ001 in China carrying antimicrobial-resistant and typhoidtoxin genes. Genomic investigation revealed a high relatedness among global S. Telelkebir isolates, suggesting potential rapid transmissions through international travels. This study highlights the importance of surveillance and understanding the threat posed by the unique combination of virulent and antimicrobial-resistant determinants in NTS infections.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Lauren K. K. Hudson, William E. E. Andershock, Xiaorong Qian, Paula L. L. Gibbs, Kelly Orejuela, Katie N. N. Garman, John R. R. Dunn, Thomas G. G. Denes
Summary: This study evaluated the clinical and epidemiological significance of Salmonella enterica subsp. enterica serovar Newport. The results showed that Newport serovar is the second most prevalent clinically isolated Salmonella serovar in the United States and can contaminate various food products. The study also identified 18 potential epidemiological clusters and highlighted the importance of this research for public health surveillance and the Salmonella research community.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Sebastian Braetz, Peter Schwerk, Nara Figueroa-Bossi, Karsten Tedin, Marcus Fulde
Summary: Our study demonstrates that prophages significantly reduce persister cell formation in lysogenic cells exposed to DNA-gyrase-targeting drugs, and also impact the initial drug susceptibility.
MICROBIOLOGY SPECTRUM
(2023)
Article
Genetics & Heredity
David R. Greig, Matthew T. Bird, Marie Anne Chattaway, Gemma C. Langridge, Emma V. Waters, Paolo Ribeca, Claire Jenkins, Satheesh Nair
Summary: Antimicrobial resistance (AMR) genes can be transferred between microbial cells via horizontal gene transfer (HGT) involving bacteriophages. Long-read sequencing is important for understanding the genomic architecture and clinical relevance of AMR mechanisms mediated by bacteriophage-mediated HGT.
MICROBIAL GENOMICS
(2022)
Article
Microbiology
Xenia Vazquez, Javier Fernandez, Margarita Bances, Pilar Lumbreras, Miriam Alkorta, Silvia Hernaez, Elizabeth Prieto, Pedro de la Iglesia, Maria de Toro, M. Rosario Rodicio, Rosaura Rodicio
Summary: This study characterized all ciprofloxacin-resistant Salmonella enterica serovar Kentucky (S. Kentucky) isolates detected in five Spanish hospitals from 2009 to 2018 through whole genome sequencing. The isolates all belonged to sequence type 198 and exhibited resistances to multiple antibiotics mediated by various resistance genes, with a close genetic relationship observed between isolates from different hospitals.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Genetics & Heredity
David R. Greig, Matthew T. Bird, Marie Anne Chattaway, Gemma C. Langridge, Emma Waters, Paolo Ribeca, Claire Jenkins, Satheesh Nair
Summary: This study discovered a novel P1-like bacteriophage-plasmid in Salmonella enterica serovar Typhi, which carries antimicrobial resistance genes. The use of long-read sequencing technology is crucial for investigating bacterial genomic architecture and understanding antimicrobial resistance mechanisms.
MICROBIAL GENOMICS
(2022)
Article
Microbiology
Danitza Xiomara Romero-Calle, Francisnei Pedrosa-Silva, Luiz Marcelo Ribeiro Tome, Thiago J. J. Sousa, Leila Thaise Santana de Oliveira Santos, Vasco Ariston de Carvalho Azevedo, Bertram Brenig, Raquel Guimaraes Benevides, Thiago M. M. Venancio, Craig Billington, Aristoteles Goes-Neto
Summary: In Brazil, Salmonella enterica serovar Enteritidis is a significant health threat. A strain of Salmonella enterica serovar Enteritidis SE3 was isolated from soil in Santo Amaro, Brazil, an area contaminated with heavy metals and organic waste. The genome analysis of this strain revealed the presence of important resistance and virulence genes, which are crucial for controlling Salmonella and heavy metal pollution in the region.
Article
Microbiology
Jianmin Zhang, Zhong Peng, Kaifeng Chen, Zeqiang Zhan, Haiyan Shen, Saixiang Feng, Hongchao Gou, Xiaoyun Qu, Mark Ziemann, Daniel S. Layton, Xiangru Wang, Huanchun Chen, Bin Wu, Xuebin Xu, Ming Liao
Summary: Through whole-genome sequencing, it was found that ST365 is the major sequence type of S. Weltevreden in diarrheal patients in China and other regions globally. Additionally, ST365 was widely recovered from animal, food, and environmental samples worldwide. The study also revealed the presence of a virulence-contributing plasmid in S. Weltevreden strains.
MICROBIOLOGY SPECTRUM
(2023)
Article
Biotechnology & Applied Microbiology
Diessy Kipper, Renato H. Orsi, Laura M. Carroll, Andrea K. Mascitti, Andre F. Streck, Andre S. K. Fonseca, Nilo Ikuta, Eduardo C. Tondo, Martin Wiedmann, Vagner R. Lunge
Summary: The study assessed the population structure, recent temporal evolution, and important genetic characteristics of multidrug-resistant Salmonella enterica serovar Heidelberg isolated from Brazilian poultry farms, revealing a monophyletic group with antibiotic resistance genes and virulence factors. This lineage poses a threat to Brazilian and global poultry operations.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Virology
Cedric Woudstra, Sophie A. Granier
Summary: This study investigates the anti-phage defenses in Salmonella Typhimurium using bioinformatics and identifies nucleic acid degradation and abortive infection mechanisms. Mobile genetic elements containing anti-phage systems were also found in Salmonella and the Enterobacteriaceae family. This research provides insights for designing preventive measures against the spread of phage resistance.
Article
Microbiology
Lijuan Luo, Michael Payne, Qinning Wang, Sandeep Kaur, Irani U. Rathnayake, Rikki Graham, Mailie Gall, Jenny Draper, Elena Martinez, Sophie Octavia, Mark M. Tanaka, Amy V. Jennison, Vitali Sintchenko, Ruiting Lan
Summary: This study analyzed 568 S. Enteritidis isolates from Australia and compared them with international strains using a multilevel genome typing database. The Australian isolates were divided into three phylogenetic clades, with clade B being the most prevalent and associated with the global epidemic lineage. Over half of the predicted multidrug resistance isolates were linked to Asian strains. This study provides important insights into the genomic epidemiology of S. Enteritidis in Australia.
MICROBIOLOGY SPECTRUM
(2023)
Article
Immunology
Mauro de Mesquita Sousa Saraiva, Valdinete Pereira Benevides, Nubia Michelle Vieira da Silva, Alessandro de Mello Varani, Oliveiro Caetano de Freitas Neto, Angelo Berchieri, Enrique Jesus Delgado-Suarez, Alan Douglas de Lima Rocha, Tadesse Eguale, Janet Agnes Munyalo, Samuel Kariuki, Wondwossen Abebe Gebreyes, Celso Jose Bruno de Oliveira
Summary: MDR Salmonella enterica subsp. enterica serovar Kentucky has emerged as a significant public health problem, especially in East Africa. This study investigated the antimicrobial resistance profile and genotypic relatedness of Salmonella Kentucky isolated from animal sources in Ethiopia and Kenya. Phylogenetic and pangenome analyses with additional publicly available genomes were used to study the evolutionary dynamics of this pathogen. The findings highlighted the importance of investigating the implications of Salmonella Kentucky to public health and its mechanisms of dissemination.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Rosemarie Slowey, Seon Woo Kim, Deirdre Prendergast, Gillian Madigan, Jo Ann S. Van Kessel, Bradd J. Haley
Summary: The study investigated the genetic diversity and antimicrobial sensitivity patterns of S. Kentucky strains isolated from non-human sources in Ireland. Most isolates belonged to ST314 and only a few were antimicrobial-resistant. The presence of multidrug-resistant ST198 in food sources in Ireland was also identified.
ZOONOSES AND PUBLIC HEALTH
(2022)
Article
Virology
Dann Turner, Hans-Wolfgang Ackermann, Andrew M. Kropinski, Rob Lavigne, J. Mark Sutton, Darren M. Reynolds
Article
Virology
Andrew M. Q. King, Elliot J. Lefkowitz, Arcady R. Mushegian, Michael J. Adams, Bas E. Dutilh, Alexander E. Gorbalenya, Balazs Harrach, Robert L. Harrison, Sandra Junglen, Nick J. Knowles, Andrew M. Kropinski, Mart Krupovic, Jens H. Kuhn, Max L. Nibert, Luisa Rubino, Sead Sabanadzovic, Helene Sanfacon, Stuart G. Siddell, Peter Simmonds, Arvind Varsani, Francisco Murilo Zerbini, Andrew J. Davison
ARCHIVES OF VIROLOGY
(2018)
Article
Virology
Evelien M. Adriaenssens, Johannes Wittmann, Jens H. Kuhn, Dann Turner, Matthew B. Sullivan, Bas E. Dutilh, Ho Bin Jang, Leonardo J. van Zyl, Jochen Klumpp, Malgorzata Lobocka, Andrea I. Moreno Switt, Janis Rumnieks, Robert A. Edwards, Jumpei Uchiyama, Poliane Alfenas-Zerbini, Nicola K. Petty, Andrew M. Kropinski, Jakub Barylski, Annika Gillis, Martha R. C. Clokie, David Prangishvili, Rob Lavigne, Ramy Karam Aziz, Siobain Duffy, Mart Krupovic, Minna M. Poranen, Petar Knezevic, Francois Enault, Yigang Tong, Hanna M. Oksanen, J. Rodney Brister
ARCHIVES OF VIROLOGY
(2018)
Article
Multidisciplinary Sciences
Piotr M. Skowron, Andrew M. Kropinski, Joanna Zebrowska, Lukasz Janus, Kasjan Szemiako, Edyta Czajkowska, Natalia Maciejewska, Malgorzata Skowron, Joanna Los, Marcin Los, Agnieszka Zylicz-Stachula
Article
Microbiology
Andrew M. Kropinski
RESEARCH IN MICROBIOLOGY
(2018)
Article
Microbiology
Vinicius da Silva Duarte, Roberto Sousa Dias, Andrew M. Kropinski, Andre da Silva Xavier, Camila Geovana Ferro, Pedro M. P. Vidigal, Cynthia Canedo da Silva, Sergio Oliveira de Paula
VETERINARY MICROBIOLOGY
(2018)
Article
Virology
Andrew M. Kropinski, Dann Turner, John H. E. Nash, Hans-Wolfgang Ackermann, Erika J. Lingohr, Richard A. Warren, Kenneth C. Ehrlich, Melanie Ehrlich
Article
Virology
Imke H. E. Korf, Jan P. Meier-Kolthoff, Evelien M. Adriaenssens, Andrew M. Kropinski, Manfred Nimtz, Manfred Rohde, Mark J. van Raaij, Johannes Wittmann
Correction
Virology
Stuart G. Siddell, Peter J. Walker, Elliot J. Lefkowitz, Arcady R. Mushegian, Bas E. Dutilh, Balazs Harrach, Robert L. Harrison, Sandra Junglen, Nick J. Knowles, Andrew M. Kropinski, Mart Krupovic, Jens H. Kuhn, Max L. Nibert, Luisa Rubino, Sead Sabanadzovic, Peter Simmonds, Arvind Varsani, Francisco Murilo Zerbini, Andrew J. Davison
ARCHIVES OF VIROLOGY
(2020)
Article
Virology
Stuart G. Siddell, Peter J. Walker, Elliot J. Lefkowitz, Arcady R. Mushegian, Bas E. Dutilh, Balazs Harrach, Robert L. Harrison, Sandra Junglen, Nick J. Knowles, Andrew M. Kropinski, Mart Krupovic, Jens H. Kuhn, Max L. Nibert, Luisa Rubino, Sead Sabanadzovic, Peter Simmonds, Arvind Varsani, Francisco Murilo Zerbini, Andrew J. Davison
ARCHIVES OF VIROLOGY
(2020)
Article
Infectious Diseases
Johannes Wittmann, Dann Turner, Andrew D. Millard, Padmanabhan Mahadevan, Andrew M. Kropinski, Evelien M. Adriaenssens
Article
Virology
Dann Turner, Andrew M. Kropinski, Evelien M. Adriaenssens
Summary: Bacteriophage taxonomy has been undergoing significant changes in recent years, with the abolition of certain classification units and the establishment of guidelines for delineating species, genus, subfamily, and family-level ranks in tailed phage taxonomy.
Article
Biotechnology & Applied Microbiology
Thomas S. Postler, Luisa Rubino, Evelien M. Adriaenssens, Bas E. Dutilh, Balazs Harrach, Sandra Junglen, Andrew M. Kropinski, Mart Krupovic, Jiro Wada, Anya Crane, Jens H. Kuhn, Arcady Mushegian, Janis Rumnieks, Sead Sabanadzovic, Peter Simmonds, Arvind Varsani, F. Murilo Zerbini, Julie Callanan, Lorraine A. Draper, Colin Hill, Stephen R. Stockdale
Summary: The International Committee on Taxonomy of Viruses has adopted a binomial naming format for virus species, which is comparable with other biological taxonomies. Latinization of these names is optional, but it provides the advantage of cultural neutrality and compatibility with other taxonomies.
JOURNAL OF GENERAL VIROLOGY
(2022)
Article
Microbiology
Dann Turner, Evelien M. Adriaenssens, Igor Tolstoy, Andrew M. Kropinski
Summary: Before submitting a bacteriophage genome sequence to the International Nucleotide Sequence Database Collaboration or writing a publication, it is important to address 14 questions to ensure an accurate and comprehensive annotation of the genome.
PHAGE-THERAPY APPLICATIONS AND RESEARCH
(2021)
Article
Virology
Cristina Moraru, Arvind Varsani, Andrew M. Kropinski