The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conditional Wwox Deletion in Mouse Mammary Gland by Means of Two Cre Recombinase Approaches

(2012) Brent W. Ferguson et al.   PLoS One

WW Domains in the Heart of Smad Regulation

(2012) Marius Sudol   STRUCTURE

Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2−:H2O2 Ratio and Confers Anoikis Resistance to Tumors

(2011) Pengcheng Zhu et al.   CANCER CELL

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

(2011) E. Aragon et al.   GENES & DEVELOPMENT

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

WWOXgene and gene product: tumor suppression through specific protein interactions

(2010) Zaidoun Salah et al.   Future Oncology

Transcriptional Profiling Identifies Functional Interactions of TGFβ and PPARβ/δ Signaling

(2010) Kerstin Kaddatz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

TGF-  Biology in Mammary Development and Breast Cancer

(2010) H. Moses et al.   Cold Spring Harbor Perspectives in Biology

Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2γ expression levels correlate with basal phenotype in breast cancer

(2009) Gulnur Guler et al.   CANCER

15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor  /  Agonist

(2009) S. Naruhn et al.   MOLECULAR PHARMACOLOGY

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

Generation and Characterization of Mice Carrying a Conditional Allele of the Wwox Tumor Suppressor Gene

(2009) John H. Ludes-Meyers et al.   PLoS One

Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells

(2008) Shunji Nakayama et al.   CANCER SCIENCE

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

Roles of TGFβ in metastasis

(2008) David Padua et al.   CELL RESEARCH

The WWOX Tumor Suppressor Is Essential for Postnatal Survival and Normal Bone Metabolism

(2008) Rami I. Aqeilan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY