Article
Green & Sustainable Science & Technology
Henrique Vieira de Mendonca, Paula Assemany, Mariana Abreu, Eduardo Couto, Alyne Martins Maciel, Renata Lopes Duarte, Marcela Granato Barbosa dos Santos, Alberto Reis
Summary: The booming human population has led to overconsumption of resources and environmental pollution, highlighting the urgent need for resource restoration. Microalgae biotechnology is seen as a key solution to addressing these challenges in the near future.
Review
Chemistry, Multidisciplinary
Chi-Ling Chiang, Ming-Huei Cheng, Chih-Hsin Lin
Summary: Research on anticancer nanomedicines has a history of over 30 years, but only a few formulations have been approved for clinical therapy. Developing nanocompartments that can selectively target points deep within malignant tissues is a promising concept, but challenges such as tumor tissue heterogeneity and low manufacturing uniformity pose obstacles to the creation of effective nanomedicines. Technological advances have improved the uniformity and efficiency of engineered nanomaterials, offering opportunities for developing more effective nanomedicines for cancer patients by combining insights of tumors and nanotechnology.
Editorial Material
Multidisciplinary Sciences
Martha I. Nelson, Elodie Ghedin
Summary: The evolutionary steps taken by the 1918 flu pandemic virus have been revealed through the analysis of lung samples stored in medical archives. Three genomes of the influenza A virus responsible for the global pandemic have been obtained, showing mutations that may have triggered the devastating second wave.
Review
Engineering, Biomedical
Ellen C. R. Leonel, Arezoo Dadashzadeh, Saeid Moghassemi, Hanne Vlieghe, Christine Wyns, Renan Orellana, Christiani A. Amorim
Summary: Acquired disorders and congenital defects of the male and female reproductive systems can have profound impacts on patients, causing sexual and endocrine dysfunction and infertility, as well as psychosocial consequences that affect their self-esteem, identity, sexuality, and relationships. Reproductive tissue engineering (REPROTEN) is a promising approach to restore fertility and improve the quality of life of patients with reproductive disorders by developing, replacing, or regenerating cells, tissues, and organs from the reproductive and urinary systems. This review explores the latest advancements in REPROTEN techniques and their applications for addressing degenerative conditions in male and female reproductive organs.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Article
Education & Educational Research
Miroslaw Pawlak
Summary: Grammar instruction in L2 pedagogy has always been controversial, with various theoretical perspectives leading to a wide array of instructional options. However, new solutions have not significantly addressed the old problems of grammar instruction.
FOREIGN LANGUAGE ANNALS
(2021)
Review
Immunology
Pawel Stachura, Olivia Stencel, Zhe Lu, Arndt Borkhardt, Aleksandra A. Pandyra
Summary: Viral-based cancer therapies, particularly using lymphocytic choriomeningitis virus (LCMV), have potential in treating poorly infiltrated tumors. LCMV is a noncytopathic virus with evolutionary mechanisms that allow it to escape the immune system. It can induce long-term responses within the tumor microenvironment, boost anti-tumor immune responses, and polarize poorly infiltrating tumors towards a hot phenotype. Other arenaviruses also have anti-tumor effects.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Polymer Science
Guido Raos, Bruno Zappone
Summary: Polymer adhesion is a complex multiscale phenomenon that requires a convergence of chemistry, physics, and engineering to solve problems. Recent research has focused on theories and simulations, experimental methods, and strategies inspired by living organisms.
Review
Oncology
George Doumat, Darine Daher, Morgan Bou Zerdan, Nasri Nasra, Hisham F. F. Bahmad, Monica Recine, Robert Poppiti
Summary: Lung cancer, particularly NSCLC, remains a major health concern with low survival rates. The heterogeneity and plasticity of CSCs contribute to the high resistance of NSCLC to treatment. Drug repurposing offers a cost-effective strategy to develop new antineoplastic purposes for existing drugs.
Article
Mathematics, Applied
Patrick E. Farrell, Abdalaziz Hamdan, Scott P. MacLachlan
Summary: This paper presents a finite element formulation for solving fourth-order problems and addresses the issue of boundary conditions. By introducing an explicit variable and using Lagrange multipliers to constrain the gradient, essential boundary conditions are enforced weakly using Nitsche's method. The problem is transformed into a saddle-point system, allowing for the development of monolithic multigrid solvers. Numerical results in two and three-dimensional cases demonstrate the accuracy of the formulation and the efficiency of the proposed solvers.
COMPUTERS & MATHEMATICS WITH APPLICATIONS
(2022)
Review
Microbiology
Junwei Fu, Ling Wang, Jingxian Sun, Ning Ju, Gang Jin
Summary: Malolactic fermentation (MLF) is crucial for wine production, but its outcomes are unpredictable and can deteriorate the wine. In recent years, MLF has faced new challenges due to climate change, winemakers' demand for efficiency, and the increasing demand for high-quality wine.
Article
Mathematics, Applied
A. Alvino, F. Chiacchio, C. Nitsch, C. Trombetti
Summary: This article discusses using symmetrization techniques to prove a comparison principle between solutions to an elliptic partial differential equation on a smooth bounded set and solutions to a related problem defined on a ball with the same volume.
JOURNAL DE MATHEMATIQUES PURES ET APPLIQUEES
(2021)
News Item
Multidisciplinary Sciences
Ewen Callaway
Summary: Genetic material collected from permafrost reveals that northern Greenland was once a thriving forest.
Review
Biochemistry & Molecular Biology
Celine Stoica, Georgina Cox
Summary: The antimicrobial resistance crisis is a global health challenge that has led to the overuse of antimicrobials in animal industry, resulting in the emergence and spread of resistance. Countries are now implementing policies to reduce the use of antimicrobials in food animals and exploring alternative strategies to maintain animal health.
CANADIAN JOURNAL OF MICROBIOLOGY
(2021)
Article
Automation & Control Systems
Luca Benvenuti, Lorenzo Farina
Summary: This review paper discusses four recent real-world application problems that require the development of long-standing theoretical open problems in positive systems research. The selected applications span various fields such as biology, medicine, civil engineering, and electronic engineering, emphasizing the extensive use of positive systems in mainstream research. The theoretical challenges arising from these applications demonstrate that the seemingly simple positivity constraint on variables of interest creates non-trivial theoretical problems, even in the linear case.
INTERNATIONAL JOURNAL OF CONTROL AUTOMATION AND SYSTEMS
(2023)
Review
Cardiac & Cardiovascular Systems
Giulia Rivasi, Andrea Ungar, Angel Moya, Michele Brignole, Richard Sutton, Artur Fedorowski
Summary: Syncope is a common occurrence in the general population, with non-cardiac syncope being more prevalent than cardiac syncope. New classification of syncope based on mechanisms has been proposed, focusing on hypotensive and bradycardic phenotypes. Advances in diagnosis and therapy have improved personalized management of syncope, with customized interventions based on phenotype.
KARDIOLOGIA POLSKA
(2021)
Article
Genetics & Heredity
Maria L. Zingaretti, Amparo Monfort, Miguel Perez-Enciso
G3-GENES GENOMES GENETICS
(2019)
Article
Fisheries
Pablo Dufflocq, Miguel Perez-Enciso, Jean P. Lhorente, Jose M. Yanez
Article
Biochemical Research Methods
Elies Ramon, Lluis Belanche-Munoz, Miguel Perez-Enciso
BMC BIOINFORMATICS
(2019)
Article
Agriculture, Dairy & Animal Science
Yuliaxis Ramayo-Caldas, Laura Zingaretti, Milka Popova, Jordi Estelle, Aurelien Bernard, Nicolas Pons, Pau Bellot, Nuria Mach, Andrea Rau, Hugo Roume, Miguel Perez-Enciso, Philippe Faverdin, Nadege Edouard, Dusko Ehrlich, Diego P. Morgavi, Gilles Renand
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2020)
Article
Genetics & Heredity
In-Cheol Cho, Hee-Bok Park, Jin Seop Ahn, Sang-Hyun Han, Jae-Bong Lee, Hyun-Tae Lim, Chae-Kyoung Yoo, Eun-Ji Jung, Dong-Hwan Kim, Wu-Sheng Sun, Yuliaxis Ramayo-Caldas, Sang-Geum Kim, Yong-Jun Kang, Yoo-Kyung Kim, Hyun-Sook Shin, Pil-Nam Seong, In-Sul Hwang, Beom-Young Park, Seongsoo Hwang, Sung-Soo Lee, Youn-Chul Ryu, Jun-Heon Lee, Moon-Suck Ko, Kichoon Lee, Goran Andersson, Miguel Perez-Enciso, Jeong-Woong Lee
Article
Agronomy
Laura M. Zingaretti, Amparo Monfort, Miguel Perez-Enciso
Summary: Automatizing phenotype measurement can significantly improve plant breeding efficiency. This study presents an automated pipeline for comprehensive phenomic and genetic analysis of morphology traits extracted from fruit images. The results demonstrate that conformational traits are heritable, with dominance variance exceeding additive components, and fruit shape and color can be quickly and automatically evaluated.
Correction
Agronomy
Laura M. Zingaretti, Amparo Monfort, Miguel Perez-Enciso
Article
Agronomy
Ioanna-Theoni Vourlaki, Raul Castanera, Sebastian E. Ramos-Onsins, Josep M. Casacuberta, Miguel Perez-Enciso
Summary: This study found that transposon insertion polymorphisms (TIPs) have advantages in improving the prediction of complex agronomic traits in rice compared to using only single nucleotide polymorphisms (SNPs), especially when the predicted materials are less related to the training materials. TIPs can explain a significant portion of the genetic variance and can improve genomic prediction. In some traits, TIPs can significantly increase the predictive correlation. This result provides evidence for the importance of TIPs in predicting complex agronomic traits.
THEORETICAL AND APPLIED GENETICS
(2022)
Correction
Agriculture, Dairy & Animal Science
Miguel Perez-Enciso, Laura M. Zingaretti, Yuliaxis Ramayo-Caldas, Gustavo de los Campos
GENETICS SELECTION EVOLUTION
(2021)
Article
Agriculture, Dairy & Animal Science
Miguel Perez-Enciso, Laura M. Zingaretti, Yuliaxis Ramayo-Caldas, Gustavo de Los Campos
Summary: The simulation results using real genotype and microbiome data suggest that microbiome data can significantly improve the accuracy of phenotype predictions. Overall, random-effects linear methods appear robust for variance components estimation.
GENETICS SELECTION EVOLUTION
(2021)
Article
Agriculture, Dairy & Animal Science
Miguel Perez-Enciso, Juan P. Steibel
Summary: Advancements in genomic technologies have allowed for industry-scale application of genomic selection, but increasing marker density up to sequence may not significantly improve genetic prediction accuracy unless causative mutations are identified. The challenges in the industry are shifting towards 'phenomics' instead of 'genomics', and developments in sensor technology and artificial intelligence are offering a wide range of analytical tools to address pressing societal demands.
GENETICS SELECTION EVOLUTION
(2021)
Article
Agriculture, Dairy & Animal Science
Miguel Perez-Enciso, Lino C. Ramirez-Ayala, Laura M. Zingaretti
GENETICS SELECTION EVOLUTION
(2020)
Meeting Abstract
Agriculture, Dairy & Animal Science
Jessica Nye, Laura Zingaretti, Miguel Perez-Enciso
JOURNAL OF ANIMAL SCIENCE
(2019)
Meeting Abstract
Agriculture, Dairy & Animal Science
Miguel Perez-Enciso
JOURNAL OF ANIMAL SCIENCE
(2019)
Correction
Agronomy
Laura M. Zingaretti, Amparo Monfort, Miguel Perez-Enciso