GP130 cytokines and bone remodelling in health and disease

Interleukin 6 is not a crucial regulator in an animal model of tumour necrosis factor-mediated bilateral sacroiliitis

(2010) S. Hayer et al.   ANNALS OF THE RHEUMATIC DISEASES

Serum levels of oncostatin M (a gp 130 cytokine): an inflammatory biomarker in periodontal disease

(2010) A.R. Pradeep et al.   BIOMARKERS

Ciliary Neurotrophic Factor Inhibits Bone Formation and Plays a Sex-Specific Role in Bone Growth and Remodeling

(2010) Narelle E. McGregor et al.   CALCIFIED TISSUE INTERNATIONAL

Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

(2010) Shigeru Kotake et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice

(2010) Emma C. Walker et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study

(2009) G. Jones et al.   ANNALS OF THE RHEUMATIC DISEASES

Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis

(2009) Heiner Appel et al.   ARTHRITIS AND RHEUMATISM

Interleukin-6 as a key player in systemic inflammation and joint destruction

(2009) J.E. Fonseca et al.   AUTOIMMUNITY REVIEWS

Evidence for the role of Th17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody

(2009) Masahiko Mihara et al.   BIOFACTORS

Role of a LIF antagonist in LIF and OSM induced MMP-1, MMP-3, and TIMP-1 expression by primary articular chondrocytes

(2009) Aradhana Upadhyay et al.   CYTOKINE

Osteoblasts derived from osteophytes produce interleukin-6, interleukin-8, and matrix metalloproteinase-13 in osteoarthritis

(2009) Kei Sakao et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Osteoblast Function Is Compromised at Sites of Focal Bone Erosion in Inflammatory Arthritis

(2009) Nicole C Walsh et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Humanin Inhibits Neuronal Cell Death by Interacting with a Cytokine Receptor Complex or Complexes Involving CNTF Receptor α/WSX-1/gp130

(2009) Yuichi Hashimoto et al.   MOLECULAR BIOLOGY OF THE CELL

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

(2008) Minoru Fujimoto et al.   ARTHRITIS AND RHEUMATISM

Serum level of CNTF is elevated in patients with amyotrophic lateral sclerosis and correlates with site of disease onset

(2008) H. Laaksovirta et al.   EUROPEAN JOURNAL OF NEUROLOGY

Early effects of tocilizumab on bone and bone marrow lesions in a collagen-induced arthritis monkey model

(2008) Atsuhiko Kato et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Immunohistochemical localization of oncostatin M in epithelialized apical periodontitis lesions

(2008) C.-H. Tsai et al.   INTERNATIONAL ENDODONTIC JOURNAL

Cardiotrophin-1 Is an Osteoclast-Derived Stimulus of Bone Formation Required for Normal Bone Remodeling

(2008) Emma C Walker et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Apoptotic Bodies Convey Activity Capable of Initiating Osteoclastogenesis and Localized Bone Destruction

(2008) Giolanta Kogianni et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

gp130 signaling in bone cell biology: Multiple roles revealed by analysis of genetically altered mice

(2008) Natalie A. Sims   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia

(2008) Aline Bozec et al.   NATURE

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

(2008) L. Pederson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-  and IL-17

(2008) M. Hashizume et al.   RHEUMATOLOGY

Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption

(2008) Natalie A. Sims et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

(2008) Morten A Karsdal et al.   ARTHRITIS RESEARCH & THERAPY

Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M

(2007) M. Durigova et al.   OSTEOARTHRITIS AND CARTILAGE