Regulation of Trib2 by an E2F1-C/EBP  feedback loop in AML cell proliferation

Tribbles in acute leukemia

(2013) K. L. Liang et al.   BLOOD

Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL

(2012) Maura M. Hannon et al.   BRITISH JOURNAL OF HAEMATOLOGY

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia

(2012) Takaomi Sanda et al.   CANCER CELL

Developmental roles of tribbles protein family members

(2012) Leonard L. Dobens et al.   DEVELOPMENTAL DYNAMICS

Multidrug Resistance Protein 4 (MRP4/ABCC4) Regulates cAMP Cellular Levels and Controls Human Leukemia Cell Proliferation and Differentiation

(2011) Sabrina Copsel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Paired-homeobox gene PITX1 by del(5)(q31) in T-cell acute lymphoblastic leukemia

(2011) Stefan Nagel et al.   LEUKEMIA & LYMPHOMA

Flavopiridol inducesBCL-2expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia

(2011) Dwella M. Nelson et al.   LEUKEMIA & LYMPHOMA

MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia

(2011) Y-S Zheng et al.   ONCOGENE

Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription

(2011) S Huseby et al.   Cell Death & Disease

C/EBP  regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations

(2010) J. A. Pulikkan et al.   BLOOD

Differential ability of Tribbles family members to promote degradation of C/EBP  and induce acute myelogenous leukemia

(2010) P. H. Dedhia et al.   BLOOD

Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding

(2010) K. Keeshan et al.   BLOOD

Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood

(2010) Candida Vaz et al.   BMC GENOMICS

Molecular mechanisms underlying deregulation of C/EBPα in acute myeloid leukemia

(2010) Kristian Reckzeh et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

E2f1–3 Are Critical for Myeloid Development

(2010) Prashant Trikha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML

(2010) J A Pulikkan et al.   LEUKEMIA

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

(2009) J. A. Pulikkan et al.   BLOOD

Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome

(2009) B. J. Wouters et al.   BLOOD

Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells

(2008) Peggy Kirstetter et al.   CANCER CELL

Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3

(2008) Bob Argiropoulos et al.   EXPERIMENTAL HEMATOLOGY

E2F in vivo binding specificity: Comparison of consensus versus nonconsensus binding sites

(2008) A. Rabinovich et al.   GENOME RESEARCH