Tribbles in acute leukemia

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

(2013) Takashi Satoh et al.   NATURE

HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis

(2012) F. O. Bagger et al.   BLOOD

Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia

(2012) T. Yokoyama et al.   BLOOD

Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL

(2012) Maura M. Hannon et al.   BRITISH JOURNAL OF HAEMATOLOGY

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia

(2012) Takaomi Sanda et al.   CANCER CELL

Leukemia Gene Atlas – A Public Platform for Integrative Exploration of Genome-Wide Molecular Data

(2012) Katja Hebestreit et al.   PLoS One

Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL

(2011) J. Tatarek et al.   BLOOD

Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation

(2011) Takashi Yokoyama et al.   CANCER SCIENCE

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors

(2011) Elena Mancini et al.   EMBO JOURNAL

Activation of Paired-homeobox gene PITX1 by del(5)(q31) in T-cell acute lymphoblastic leukemia

(2011) Stefan Nagel et al.   LEUKEMIA & LYMPHOMA

Stem cell gene expression programs influence clinical outcome in human leukemia

(2011) Kolja Eppert et al.   NATURE MEDICINE

Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα

(2011) K B Grandinetti et al.   ONCOGENE

Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis

(2010) T. Yokoyama et al.   BLOOD

Differential ability of Tribbles family members to promote degradation of C/EBP  and induce acute myelogenous leukemia

(2010) P. H. Dedhia et al.   BLOOD

Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding

(2010) K. Keeshan et al.   BLOOD

Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group

(2010) Torsten Haferlach et al.   JOURNAL OF CLINICAL ONCOLOGY

Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features

(2009) M. E. Figueroa et al.   BLOOD

Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia

(2009) Daniel C. Gilby et al.   IMMUNOLOGY LETTERS

Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3

(2008) Bob Argiropoulos et al.   EXPERIMENTAL HEMATOLOGY

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY

Evidence for Hox and E2A–PBX1 collaboration in mouse T-cell leukemia

(2008) J Bijl et al.   ONCOGENE

Tribbles homolog 2 (Trib2) and HoxA9 cooperate to accelerate acute myelogenous leukemia

(2007) Karen Keeshan et al.   BLOOD CELLS MOLECULES AND DISEASES