Autonomous growth and increased cytotoxicity of natural killer cells expressing membrane-bound interleukin-15

A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells

(2013) Y.-H. Chang et al.   CANCER RESEARCH

Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

(2013) Wei Liao et al.   IMMUNITY

Characterization and Favorablein VivoProperties of Heterodimeric Soluble IL-15·IL-15Rα Cytokine Compared to IL-15 Monomer

(2013) Elena Chertova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation

(2012) Anjali Mishra et al.   CANCER CELL

Interleukin 2 in Cancer Therapy

(2012) G. K. Antony et al.   CURRENT MEDICINAL CHEMISTRY

Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications

(2012) Natalia Lapteva et al.   CYTOTHERAPY

A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies

(2012) Noriko Shimasaki et al.   CYTOTHERAPY

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

(2011) T. A. Waldmann et al.   BLOOD

Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients

(2011) A. Curti et al.   BLOOD

IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood

(2011) M. C. Sneller et al.   BLOOD

Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression

(2011) M. R. Parkhurst et al.   CLINICAL CANCER RESEARCH

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

(2011) Nicolas F Delahaye et al.   NATURE MEDICINE

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

(2010) E. Lugli et al.   BLOOD

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

Tumor Antigen–Targeted, Monoclonal Antibody–Based Immunotherapy: Clinical Response, Cellular Immunity, and Immunoescape

(2010) Robert L. Ferris et al.   JOURNAL OF CLINICAL ONCOLOGY

NKAML: A Pilot Study to Determine the Safety and Feasibility of Haploidentical Natural Killer Cell Transplantation in Childhood Acute Myeloid Leukemia

(2010) Jeffrey E. Rubnitz et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety and immunologic effects of IL-15 administration in nonhuman primates

(2009) C. Berger et al.   BLOOD

Replicative potential of human natural killer cells

(2009) Hiroyuki Fujisaki et al.   BRITISH JOURNAL OF HAEMATOLOGY

Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy

(2009) H. Fujisaki et al.   CANCER RESEARCH

Caspases and Kinases in a Death Grip

(2009) Manabu Kurokawa et al.   CELL