Interaction of platelet-derived autotaxin with tumor integrin  V 3 controls metastasis of breast cancer cells to bone

Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions

(2014) Matthew G.K. Benesch et al.   FEBS LETTERS

Autotaxin: structure-function and signaling

(2014) Anastassis Perrakis et al.   JOURNAL OF LIPID RESEARCH

Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor

(2013) Dagmar Schumacher et al.   CANCER CELL

Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration

(2013) Tao Wu et al.   FASEB JOURNAL

Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy

(2012) David N. Brindley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Benzyl and Naphthalene Methylphosphonic Acid Inhibitors of Autotaxin with Anti-invasive and Anti-metastatic Activity

(2011) Renuka Gupte et al.   ChemMedChem

Binding of Autotaxin to Integrins Localizes Lysophosphatidic Acid Production to Platelets and Mammalian Cells

(2011) Zachary Fulkerson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The phospholipase A1activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation

(2011) Alyssa L. Bolen et al.   JOURNAL OF LIPID RESEARCH

Structural basis of substrate discrimination and integrin binding by autotaxin

(2011) Jens Hausmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cancer Cell Expression of Autotaxin Controls Bone Metastasis Formation in Mouse through Lysophosphatidic Acid-Dependent Activation of Osteoclasts

(2010) Marion David et al.   PLoS One

Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

(2009) Shuying Liu et al.   CANCER CELL

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

(2008) Hidenobu Kanda et al.   NATURE IMMUNOLOGY