The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice

(2009) Z. Song et al.   BLOOD

Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration

(2009) Wolfram Goessling et al.   CELL

Secreted Frizzled-Related Protein 1 Extrinsically Regulates Cycling Activity and Maintenance of Hematopoietic Stem Cells

(2009) Jonas Renström et al.   Cell Stem Cell

Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion

(2009) M. Ximeri et al.   HAEMATOLOGICA

Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer

(2009) B L Ebert   LEUKEMIA

Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q− syndrome

(2009) O Lopez-Villar et al.   LEUKEMIA

Dysregulated gene expression networks in human acute myelogenous leukemia stem cells

(2009) R. Majeti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo

(2008) Heather E. Fleming et al.   Cell Stem Cell

The Signaling Protein Wnt4 Enhances Thymopoiesis and Expands Multipotent Hematopoietic Progenitors through β-Catenin-Independent Signaling

(2008) Isabelle Louis et al.   IMMUNITY

A critical role for Apc in hematopoietic stem and progenitor cell survival

(2008) Zhijian Qian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

(2008) Benjamin L. Ebert et al.   NATURE