A zinc-finger transcriptional activator designed to interact with the  -globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts

Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

(2009) O. Sripichai et al.   BLOOD

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

(2009) M. Hoogenkamp et al.   BLOOD

Amelioration of murine  -thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both  -globin and the MGMT drug-resistance gene

(2009) H. Zhao et al.   BLOOD

SCF induces  -globin gene expression by regulating downstream transcription factor COUP-TFII

(2009) W. Aerbajinai et al.   BLOOD

Discovering the genetics underlying foetal haemoglobin production in adults

(2009) Swee Lay Thein et al.   BRITISH JOURNAL OF HAEMATOLOGY

Dynamics of α-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34+ cells in culture

(2009) Milind C. Mahajan et al.   EXPERIMENTAL HEMATOLOGY

Developmental and species-divergent globin switching are driven by BCL11A

(2009) Vijay G. Sankaran et al.   NATURE

Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

(2008) G. D. Trobridge et al.   BLOOD

Hemoglobin research and the origins of molecular medicine

(2008) A. N. Schechter   BLOOD

A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger

(2008) Rodwell Mabaera et al.   EXPERIMENTAL HEMATOLOGY

Ikaros and GATA-1 Combinatorial Effect Is Required for Silencing of Human  -Globin Genes

(2008) S. Bottardi et al.   MOLECULAR AND CELLULAR BIOLOGY

Silencing of A -Globin Gene Expression during Adult Definitive Erythropoiesis Mediated by GATA-1-FOG-1-Mi2 Complex Binding at the -566 GATA Site

(2008) S. Harju-Baker et al.   MOLECULAR AND CELLULAR BIOLOGY

Hydroxyurea for the Treatment of Sickle Cell Anemia

(2008) Orah S. Platt   NEW ENGLAND JOURNAL OF MEDICINE

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE