First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors

An in silico approach for the discovery of CDK5/p25 interaction inhibitors

(2011) Bing Zhang et al.   Biotechnology Journal

Using BRET to study chemical compound-induced disruptions of the p53-HDM2 interactions in live cells

(2010) Anne Mazars et al.   Biotechnology Journal

Inhibiting the Cyclin-Dependent Kinase CDK5 Blocks Pancreatic Cancer Formation and Progression through the Suppression of Ras-Ral Signaling

(2010) Georg Feldmann et al.   CANCER RESEARCH

Cyclin-dependent kinase inhibitors: a survey of recent patent literature

(2010) Hervé Galons et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Molecular mechanisms of neurodegeneration in Alzheimer's disease

(2010) L. Crews et al.   HUMAN MOLECULAR GENETICS

A 24-Residue Peptide (p5), Derived from p35, the Cdk5 Neuronal Activator, Specifically Inhibits Cdk5-p25 Hyperactivity and Tau Hyperphosphorylation

(2010) Ya-Li Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of CDK5/p35 in resected patients with non-small cell lung cancer: relation to prognosis

(2010) Jun-Li Liu et al.   MEDICAL ONCOLOGY

Delayed Treatment with Systemic (S)-Roscovitine Provides Neuroprotection and Inhibits In Vivo CDK5 Activity Increase in Animal Stroke Models

(2010) Bénédicte Menn et al.   PLoS One

Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics

(2009) Lindsay O. Kirkland et al.   BIOCHEMICAL PHARMACOLOGY

Identification of potential cellular targets of aloisine A by affinity chromatography

(2009) Caroline Corbel et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Biosensing and imaging based on bioluminescence resonance energy transfer

(2009) Zuyong Xia et al.   CURRENT OPINION IN BIOTECHNOLOGY

Explaining the inhibition of cyclin-dependent kinase 5 by peptides derived from p25 with molecular dynamics simulations and MM-PBSA

(2009) Vincent B. C. Tan et al.   JOURNAL OF MOLECULAR MODELING

A toxin–antitoxin module as a target for antimicrobial development

(2009) Virginia S. Lioy et al.   PLASMID

The BRET technology and its application to screening assays

(2008) Johan Bacart et al.   Biotechnology Journal

An Unusual Member of the Cdk Family: Cdk5

(2008) Fatema A. Dhariwala et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

ATP-Noncompetitive Inhibitors of CDK-Cyclin Complexes

(2008) Mar Orzáez et al.   ChemMedChem

Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

(2008) Déborah Tribouillard-Tanvier et al.   PLoS One