Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum

标题
Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum
作者
关键词
Methotrexate, 7-Hydroxy methotrexate, DAMPA, Carboxypeptidase-G2, Therapeutic drug monitoring, Mass spectrometry, Turbulent flow liquid chromatography, Method correlation, Dihydrofolate reductase inhibition assay, Fluorescence polarization immunoassay
出版商
Elsevier BV
发表日期
2015-08-23
DOI
10.1016/j.jchromb.2015.08.025

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