Article
Chemistry, Multidisciplinary
Yutong Yang, Meng Li, Guoying Pan, Jueying Chen, Baolin Guo
Summary: Self-adaptive wound dressings with multiple stimuli-responsiveness and antibacterial activity have been developed to meet the therapeutic needs of different stages in infected wound healing.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Wanhe Luo, Yongtao Jiang, Jinhuan Liu, Mujie Ju, Samah Attia Algharib, Ali Sobhy Dawood
Summary: In this study, enrofloxacin (ENR) was encapsulated in oxidized hyaluronic acid (OHA) and chitosan oligosaccharide (COS) to achieve on-demand release in the micro-environment of bacterial-infected wounds. The ENR nanogels showed pH and HAase-responsiveness, as well as strong antibacterial activity and accelerated wound healing. The results suggest the great potential of ENR nanogels as biocompatible wound dressings for infected wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Gan Xu, Na Xu, Tingjie Ren, Changyou Chen, Jiangfeng Li, Liangping Ding, Yang Chen, Guoqiang Chen, Zheng Li, Yunlong Yu
Summary: A multifunctional chitosan/silver/tannic acid cryogel has been prepared for hemostasis and wound healing. The cryogel exhibits stability, compressibility, and good antibacterial ability. It can scavenge free radicals and promote cell proliferation, significantly enhancing wound repair.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Seiichi Ohta, Kento Mitsuhashi, Arvind K. Singh Chandel, Pan Qi, Noriko Nakamura, Akiko Nakamichi, Hiromi Yoshida, Gento Yamaguchi, Yuichi Hara, Ryo Sasaki, Masaya Fuke, Madoka Takai, Taichi Ito
Summary: Silver-loaded CMC nonwoven sheets with different counterions, CMC-Na/Ag and CMC-H/Ag, showed differences in anti-bacterial and wound-healing properties. CMC-Na/Ag significantly accelerated wound healing in a pressure ulcer mouse model compared to CMC-H/Ag and a commercial product Aquacel Ag.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Jia Chen, Yu Xia, Qian Lan, Min Hu, Yueying Xu, Quanxin Wu, Xinguang Liu, Yun Liu
Summary: In order to address uncontrolled hemorrhage in pre-hospital emergencies, it is necessary to develop novel composite materials with fast hemostasis, synergistic antibacterial properties, and wound healing acceleration. In this study, multifunctional SCTF cryogels were fabricated using a combination of sodium alginate, tannic acid, and Fe3+ ions. The cryogels exhibited photothermal effect, enhanced Fenton activity, and dual-responsive release of antibacterial compounds. In vitro and in vivo assays demonstrated their excellent hemostatic capacity, as well as enhanced bactericidal efficacy through photothermal therapy, chemodynamic therapy, and pH/photothermal-responsive chemo-therapy. Animal experiments confirmed their outstanding wound healing acceleration, making them a promising candidate for future clinical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Organic
Luke O. Jones, Leah Williams, Tasmin Boam, Martin Kalmet, Chidubem Oguike, Fiona L. Hatton
Summary: Cryogels are macroporous polymeric structures formed by cryogelation of monomers/polymer in a solvent below freezing temperature. They are increasingly being used in biomedical applications such as 3D bioprinting, drug delivery, wound healing, and injectable therapeutics due to their interconnected macroporosity, ease of preparation, and biocompatibility. Recent studies have shown promising results in using cryogels for cancer treatment, surgical implantation, and wound dressings.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Engineering, Multidisciplinary
Dan Liu, Jiajun Qiu, Ru Xu, Junyu Liu, Jiayin Feng, Liping Ouyang, Shi Qian, Yuqin Qiao, Xuanyong Liu
Summary: The BPP hydrogel is a highly stretchable, biocompatible, and antibacterial dressing that exhibits excellent wound closure effectiveness, offering complete protection even in special scenarios. The research demonstrates the potential and clinical applicability of the BPP hydrogel in wound healing.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Raluca Nicu, Diana Elena Ciolacu, Anca-Roxana Petrovici, Daniela Rusu, Mihaela Avadanei, Andreea Cristina Mihaila, Elena Butoi, Florin Ciolacu
Summary: Current trends in wound dressing development are focused on biopolymer-based materials with unique properties that are advantageous for therapy, such as non-toxicity, hydrophilicity, biocompatibility, and biodegradability. This study aims to develop hydrogels based on cellulose and dextran (CD) and investigate their anti-inflammatory performance. Plant bioactive polyphenols (PFs) were incorporated into CD hydrogels. Various assessments, including structural characteristics, morphology, swelling degree, PFs release kinetics, cytotoxicity, and anti-inflammatory properties, were conducted. The results showed that dextran improved the structure of the hydrogels, leading to decreased pore size, increased pore uniformity and interconnectivity. The swelling degree and encapsulation capacity of PFs increased with higher dextran content. The PFs release kinetics depended on the composition and morphology of the hydrogels. CD hydrogels promoted cell proliferation without cytotoxicity, and the PFs-loaded hydrogels exhibited anti-inflammatory properties. These findings provide conclusive evidence of wound healing acceleration through inhibition of the inflammation process, supporting the use of PFs encapsulated hydrogels in wound healing applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Chiara Zagni, Alessandro Coco, Tommaso Mecca, Giusy Curcuruto, Vincenzo Patamia, Katia Mangano, Antonio Rescifina, Sabrina Carola Carroccio
Summary: New drug delivery systems based on alpha/beta/gamma-cyclodextrin (CD) acrylic and styrenic monomers were synthesized and loaded with lomefloxacin (LOM), piroxicam (PIR), and fluconazole (FLU). The presence of CDs within cryogels improved the loading capacity and drug delivery efficiency. CD derivatives successfully achieved multi-drug release, demonstrating their potential for wound healing applications.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Emergency Medicine
Na Xu, Yucheng Yuan, Liangping Ding, Jiangfeng Li, Jiezhi Jia, Zheng Li, Dengfeng He, Yunlong Yu
Summary: The multifunctional cryogel possesses properties of fast hemostasis, antibacterial effect, anti-inflammation and promotion of cell proliferation, making it suitable for the treatment of bacterial infected wounds.
Article
Biochemistry & Molecular Biology
Xiaotong Yi, Jinmei He, Xinjing Wei, Hongbin Li, Xingyuan Liu, Feng Cheng
Summary: Hydrogels with multiple functions have gained attention in the biomedical materials field. A novel hydrogel wound dressing (PB-EPL/TA@BC) was developed by incorporating bacterial cellulose modified with tannic acid and & epsilon;-polylysine into a PVA and borax matrix. The hydrogel showed good adhesion, mechanical properties, and inhibition against bacteria without antibiotics. It also exhibited cytocompatibility and biocompatibility, achieved hemostasis within 120 s, and accelerated wound healing process.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Xuyan Lu, Zirui Liu, Qirui Jia, Qiusheng Wang, Qi Zhang, Xiaoran Li, Jianyong Yu, Bin Ding
Summary: Self-expanding cryogels with unique properties have potential for treating uncontrollable hemorrhages. In this study, a superelastic cellular-structured bioactive glass nanofibrous cryogel (BGNC) was developed, showing high absorption capacity, fast self-expanding ability, injectability, and good tissue adhesion. The BGNCs demonstrated superior hemostatic capacity in animal models and promoted wound healing. These findings offer a promising strategy for the development of multifunctional hemostatic and wound repair materials.
Article
Polymer Science
Ali Afzal, Mohammed Jalalah, Abid Noor, Zubair Khaliq, Muhammad Bilal Qadir, Rashid Masood, Ahsan Nazir, Sheraz Ahmad, Faheem Ahmad, Muhammad Irfan, Munazza Afzal, Mohd Faisal, Saeed A. Alsareii, Farid A. Harraz
Summary: Nowadays, synthetic polymers with special properties such as biodegradability, biocompatibility, hydrophilicity, and non-toxicity are widely used in medical applications. This study aims to develop and characterize PVA/PCL fibers containing a model drug for controlled drug release in wound dressing. The wet spinning technique was used to produce PVA/PCL fibers from a dope solution, and the fibers were tested for various properties related to wound healing. The results showed that the developed PVA/PCL fibers have respectable tensile properties, adequate liquid absorption, swelling behavior, degradation, and antimicrobial activity, as well as a controlled drug release profile.
Article
Medicine, Research & Experimental
Asad Ullah, Abdulla Al Mamun, Midhat Batool Zaidi, Talat Roome, Anwarul Hasan
Summary: Impaired wound healing is a common problem in diabetes patients, leading to severe complications. Chronic hypoxia is a major factor in delayed wound healing. This study developed a hydrogel containing oxygen-releasing nanoparticles to provide sustained delivery of oxygen. In vitro and in vivo experiments showed improved biocompatibility, cell proliferation, and migration, leading to accelerated wound closure in diabetic rat model.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Biochemistry & Molecular Biology
Qi Zhang, Miao Zhang, Teng Wang, Xiangyan Chen, Quancai Li, Xia Zhao
Summary: Maintaining a moist and sterile environment is beneficial for wound healing. A novel natural multifunctional hydrogel, combining Aloe polysaccharide (AP) and honey, was prepared for infected wound healing. The hydrogel exhibited good water retention capacity, antibacterial activity, and accelerated the healing of infected wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Pharmacology & Pharmacy
Tugce Boztepe, Guillermo R. Castro, Ignacio E. Leon
Summary: Platinum drugs like carboplatin, cisplatin, and oxaliplatin are widely used in cancer treatment but their toxicity limits their application. Recent research focuses on developing new formulations to expand therapeutic options. Advances in drug delivery carriers aim to increase drug stability and reduce toxic effects.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Biotechnology & Applied Microbiology
Susana Calderon-Toledo, Manuel Horue, Vera A. Alvarez, Guillermo R. Castro, Amparo Iris Zavaleta
Summary: The study successfully isolated a wild-type strain identified as K. rhaeticus SU12 capable of producing BC using a synthetic medium supplemented with mango wastes extracts. Through optimization of relevant parameters, a high BC production of 25.34 g L-1 dry cellulose in 21 days was achieved, demonstrating the potential of utilizing mango wastes for valuable BC production.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2022)
Article
Pharmacology & Pharmacy
Giuliana S. Muraca, Juliana Soler-Arango, Guillermo R. Castro, German A. Islan, Graciela Brelles-Marino
Summary: Antibiotic resistance presents a significant challenge in clinical practice, leading researchers to explore new approaches combining non-thermal plasma and nanotechnology to combat multidrug-resistant strains and resilient biofilms. The use of non-thermal plasma has shown effectiveness in inactivating biofilm cells, while nanotechnology-based drug delivery systems like nanostructured lipid carriers (NLCs) offer potential for overcoming antibiotic resistance in biofilms. Synergy between NLCs and NTP was not observed in this study, suggesting the need for further research to optimize conditions for enhanced efficacy.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Applied
Nadia Andrade Aleixo, Pietra Stefany da Silva Gomes, Patricia Bento da Silva, Mariana Rillo Sato, Debora Leite Campos, Hernane da Silva Barud, Guillermo Raul Castro, German Abel Islan, Constanza Toledo, Federico Karp, Marlus Chorilli, Fernando Rogerio Pavan, Flavia Aparecida Resende
Summary: This study aimed to encapsulate and characterise a potential anti-tuberculosis copper complex into polymeric nanoparticles of polymethacrylate copolymers. Different polymers were tested and their physicochemical characterisations were analyzed. The encapsulation efficiency, particle size, zeta potentials, and release studies were measured. The results showed that PN-E100 had the highest encapsulation efficiency of 94.5% and PN-NE30D had the highest release rate of I1. PN-NE30D also demonstrated moderate inhibition of M. tuberculosis without mutagenicity.
JOURNAL OF MICROENCAPSULATION
(2022)
Review
Biotechnology & Applied Microbiology
German A. Islan, Boris Rodenak-Kladniew, Nehuen Noacco, Nelson Duran, Guillermo R. Castro
Summary: This review summarizes the general aspects of prodigiosin (PG), a bio-dye with a wide spectrum of biological activities. The synthesis, production process, and potential delivery systems for improving its bioavailability are discussed. Additionally, novel applications to enhance its biological activity in biomedical applications are proposed.
Article
Pharmacology & Pharmacy
Carolina Medina-Montano, Ignacio Rivero Berti, Rocio C. Gambaro, Maria Jose Limeres, Malin Svensson, Gisel Padula, Cecilia Y. Chain, Jose Sebastian Cisneros, Guillermo R. Castro, Stephan Grabbe, Matthias Bros, Stephan Gehring, German A. Islan, Maximiliano L. Cacicedo
Summary: Nanostructured lipid carriers are a reliable platform for encapsulating and releasing dexamethasone, which showed good tolerance by non-parenchymal liver cells and preserved its anti-inflammatory activity, suggesting its potential for treating pathologies associated with chronic liver inflammation.
Article
Chemistry, Analytical
Maria Florencia Ladetto, Juan Manuel Lazaro-Martinez, Tomas Brito Devoto, Victor J. Briceno, Guillermo R. R. Castro, Maria Lujan Cuestas
Summary: The present study aimed to develop a simple, accessible, and affordable spectrophotometric technique for the quantification of Voriconazole (VCZ). The method is based on VCZ-induced reduction of thionine (TH) to leucothionine (LTH) under alkaline conditions. The technique showed linear correlation and was validated according to the ICH Q2 (R1) guidelines, proving its applicability in commercially available tablets.
ANALYTICAL METHODS
(2023)
Article
Engineering, Chemical
Lisbeth Benavides Castillo, Yanina Martinez
Summary: In this study, we investigated the impact of increasing concentrations of different emulsifiers on the size distribution of a simple emulsion (O/W) and double emulsion (W/OW). We found that increasing the concentration of polycaprolactone (PCL) led to smaller droplets in the O/W emulsion. Conversely, increasing the concentration of polyvinyl alcohol (PVA), pluronic f68, or bovine serum albumin (BSA) in the W/O/W emulsion resulted in micrometer-sized droplets up to 7 μm. Additionally, increasing pluronic f68 concentration led to a transition from polydisperse to monodisperse size distribution in the double emulsion. Our findings indicate that pluronic has a more stabilizing effect on the emulsion compared to PVA or BSA. Moreover, we used Focused Ion Beam technique combined with Scanning Electron Microscopy (FIB-SEM) to examine the inner morphology of the W/O/W emulsion and confirmed the formation of a double emulsion. These results have significant implications for cosmetics and pharmaceutical applications, as achieving a monodisperse size distribution and characterizing the inner morphology of microspheres are crucial factors.
CHEMICAL ENGINEERING COMMUNICATIONS
(2023)
Article
Pharmacology & Pharmacy
Amedea B. Seabra, Joana C. Pieretti, Bianca de Melo Santana, Manuel Horue, Gonzalo R. Tortella, Guillermo R. Castro
Summary: Nitric oxide (NO) is synthesized in human skin and plays various roles in wound healing, vasodilation, and skin defense. NO-based dermatological formulations have been developed for bacterial infection, wound healing, leishmaniasis, acne, and skin aging. Recent advancements focus on smart NO-releasing nanomaterials/biomaterials for targeted and sustained release, improving therapeutic effects.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Pharmacology & Pharmacy
Boris Rodenak-Kladniew, Rocio Gambaro, Jose S. Cisneros, Cristian Huck-Iriart, Gisel Padula, Guillermo R. Castro, Cecilia Y. Chain, German A. Islan
Summary: Geraniol (GOH), a monoterpene alcohol found in essential oils, was encapsulated into nanostructured lipid carriers (NLC) to improve its anticancer activity. The NLC/GOH exhibited high stability and low dispersity, and showed increased release of GOH at acidic pH. The NLC/GOH were safe, absorbed serum proteins, and preferentially interacted with human serum albumin. A time-dependent cellular uptake of NLC/GOH was observed in A549 cells, leading to increased cytotoxicity, mitochondrial membrane depolarization, and cell death. NLC/GOH showed highly cytotoxic concentrations against A549 cells but was non-toxic to normal lung fibroblasts. Additionally, GOH nanoencapsulation into NLC potentiated the inhibition of A549 cell migration.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Polymer Science
Veronica E. Passamai, Sergio Katz, Boris Rodenak-Kladniew, Vera Alvarez, Guillermo R. Castro
Summary: 3D bioprinting enables the development of customized dressings for tissue regeneration and wound healing. This study formulated three biopolymeric inks and conducted various tests to evaluate their performance. The results suggest that Pectin (Pe) and Pectin + Microcrystalline cellulose (MCC) inks have the potential to be used in 3D printed personalized dressings for wound healing treatment.
JOURNAL OF POLYMER RESEARCH
(2023)
Review
Pharmacology & Pharmacy
Manuel Horue, Jhonatan Miguel Silva, Ignacio Rivero Berti, Larissa Reis Brandao, Hernane da Silva Barud, Guillermo R. R. Castro
Summary: Bacterial cellulose (BC), produced by microorganisms, can be modified to produce different cellulosic formats. BC has advantages for biomedical applications such as easy moldability, high biocompatibility, and tailoring ability. Its hydroxyl residues and nanoporous morphology make it ideal for wound healing. This article discusses the characteristics of different BC structures, recent advances in BC composites, and the development of antimicrobial BC and drug delivery systems.
Article
Pharmacology & Pharmacy
Tugce Boztepe, Sebastian Scioli-Montoto, Rocio C. Gambaro, Maria Esperanza Ruiz, Silvia Cabrera, Jose Aleman, German A. Islan, Guillermo R. Castro, Ignacio E. Leon
Summary: Colorectal cancer, the second leading cause of cancer death, is referred to as colon or rectal cancer depending on the site of formation. The platinum-based compound 8-QO-Pt has shown promising anticancer activity. In this study, three different systems of 8-QO-Pt-encapsulated nanostructured lipid carriers (NLCs) with riboflavin (RFV) were investigated. The results demonstrated the higher cytotoxicity of the 8-QO-Pt-loaded NLC/RFV formulations compared to free 8-QO-Pt, indicating the potential of RFV-targeted NLC systems for colon cancer treatment.
Article
Pharmacology & Pharmacy
Boris Rodenak-Kladniew, Maria Agustina Castro, Rocio Celeste Gambaro, Juan Girotti, Jose Sebastian Cisneros, Sonia Vina, Gisel Padula, Rosana Crespo, Guillermo Raul Castro, Stephan Gehring, Cecilia Yamil Chain, German Abel Islan
Summary: This study evaluated the cytotoxic activity of several plant and herbal essential oils against human lung and colon cancer cells, finding that Lippia alba and Clinopodium nepeta oils exhibited strong anticancer effects. Encapsulating these oils into solid lipid nanoparticles significantly enhanced their anticancer activity.
Article
Chemistry, Multidisciplinary
Maria Emilia Zelaya-Soule, Manuel Horue, Rosa Maria Torres Sanchez, Guillermo Raul Castro, Daniel Osvaldo Martire, Mariela Alejandra Fernandez, Valeria Beatriz Arce
Summary: The antibiotic norfloxacin can be adsorbed on clay and carbon-clay nanocomposites while maintaining its antimicrobial activity. Direct and indirect photolysis experiments showed that carbon samples performed better than clay samples in the photolysis of norfloxacin, highlighting the importance of oxygenated carbonaceous groups.
COMPTES RENDUS CHIMIE
(2022)
Article
Agricultural Engineering
Yinping Xiang, Meiying Jia, Rui Xu, Jialu Xu, Lele He, Haihao Peng, Weimin Sun, Dongbo Wang, Weiping Xiong, Zhaohui Yang
Summary: This study investigated the impact of the non-antibiotic pharmaceutical carbamazepine on antibiotic resistance genes (ARGs) during anaerobic digestion. The results showed that carbamazepine induced the enrichment of ARGs and increased the abundance of bacteria carrying these genes. It also facilitated microbial aggregation and intercellular communication, leading to an increased frequency of ARGs transmission. Moreover, carbamazepine promoted the acquisition of ARGs by pathogens and elevated their overall abundance.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Weixin Zhao, Tianyi Hu, Hao Ma, Dan Li, Qingliang Zhao, Junqiu Jiang, Liangliang Wei
Summary: This review summarizes the effects and potential mechanisms of biochar on microbial behavior in AD systems. The addition of biochar has been found to promote microbial colonization, alleviate stress, provide nutrients, and enhance enzyme activity. Future research directions include targeted design of biochar, in-depth study of microbial mechanisms, and improved models.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Christina Karmann, Anna Magrova, Pavel Jenicek, Jan Bartacek, Vojtech Kouba
Summary: This review assesses nitrogen removal technologies in reject water treatment, highlighting the differences in environmental impacts and economic benefits. Partial nitritation-anammox shows potential for economic benefits and positive environmental outcomes when operated and controlled properly.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Wei-Hao Huang, Ying-Ju Chang, Duu-Jong Lee
Summary: This study modified pinecone biochar with layered double hydroxide (LDH) to enhance its adsorption capacity for heavy metal and phosphate ions. The LDH-biochar showed significantly improved adsorption capacities for Pb2+ and phosphate, and a slight increase for Cu2+ and Co2+. The LDH layer enhanced the adsorption through various mechanisms.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Chao Song, Fanfan Cai, Shuang Yang, Ligong Wang, Guangqing Liu, Chang Chen
Summary: This paper developed a machine learning model to predict the biochemical methane potential during anaerobic digestion. Model analysis identified lignin content, organic loading, and nitrogen content as key attributes for methane production prediction. For feedstocks with high cellulose content, early methane production is lower but can be improved by prolonging digestion time. Moreover, lignin content exceeding a certain value significantly inhibits methane production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sang Min Lee, Ju Young Lee, Ji-Sook Hahn, Seung-Ho Baek
Summary: This study successfully developed an efficient platform strain using Yarrowia lipolytica for the bioconversion of renewable resources into adipic acid, achieving a remarkable increase in production level.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sefkan Kendir, Matthias Franzreb
Summary: This study presents a novel approach using magnetic separation to efficiently harvest freshwater microalgae, Chlorella vulgaris. By combining pH-induced calcium phosphate precipitation with cheap natural magnetite microparticles, harvesting efficiencies up to 98% were achieved in the model medium.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Ishaq Kariim, Ji-Yeon Park, Wajahat Waheed Kazmi, Hulda Swai, In-Gu Lee, Thomas Kivevele
Summary: The impact of reaction temperature, residence time, and ethanol: acetone on the energy compositions and yield enhancement of biocrudes was investigated. The results showed that under appropriate conditions, biocrudes with high energy and low oxygen content can be obtained, indicating a high potential for utilization.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xiyue Zhang, Xiyao Li, Liang Zhang, Yongzhen Peng
Summary: Intermittent aeration is an innovative approach to enhance nitrogen removal in low carbon-to-nitrogen ratio municipal sewage, providing an efficient strategy for the continuous plug-flow AOA process.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xu Yang, Mahmoud Mazarji, Mengtong Li, Aohua Li, Ronghua Li, Zengqiang Zhang, Junting Pan
Summary: This study investigated the impact of magnetite on the nitrogen cycle of pig manure biostabilisation. The addition of magnetite increased N2O emissions and decreased NH3 emissions during composting. It also increased the total nitrogen content but should be considered for its significant increase in N2O emissions in engineering practice.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Ty Shitanaka, Haylee Fujioka, Muzammil Khan, Manpreet Kaur, Zhi-Yan Du, Samir Kumar Khanal
Summary: The market value of microalgae has exponentially increased in the past two decades, thanks to their applications in various industries. However, the supply of high-value microalgal bioproducts is limited due to several factors, and strategies are being explored to overcome these limitations and improve microalgae production, thus increasing the availability of algal-derived bioproducts in the market.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Martin Kerner, Thorsten Wolff, Torsten Brinkmann
Summary: The efficiency of using enriched CO2 from flue gas for large-scale production of green microalgae has been studied. The results show that the use of membrane devices and static mixers can effectively improve the CO2 recovery rate and maintain the suitable pH and temperature during cultivation, achieving a more economical and sustainable microalgae production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rui Ma, Ji Li, Rd Tyagi, Xiaolei Zhang
Summary: This review summarizes the microorganisms capable of using CO2 and CH4 to produce PHAs, illustrating the production process, factors influencing it, and discussing optimization techniques. It identifies the challenges and future prospects for developing economically viable PHAs production using GHGs as a carbon source.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Bing Wang, Peng Zhang, Xu Guo, Xu Bao, Junjie Tian, Guomin Li, Jian Zhang
Summary: The addition of zeolite in the co-composting of chicken manure and straw significantly reduced the emissions of ammonia and N2O, and increased the nitrate content. Zeolite also promoted the abundance of nitrification genes and inhibited the expression of denitrification genes.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rohit Dey, Franziska Ortiz Tena, Song Wang, Josef Martin Messmann, Christian Steinweg, Claudia Thomsen, Clemens Posten, Stefan Leu, Matthias S. Ullrich, Laurenz Thomsen
Summary: This study investigated the operation of a 1000L microalgae-based membrane photobioreactor system for continuous secondary wastewater treatment. The research focused on a green microalgae strain called Desmodesmus sp. The study aimed to understand key trends and optimization strategies by conducting experiments in both summer and winter seasons. The findings showed that maintaining low cell concentrations during periods of light inhibition was beneficial for nutrient uptake rates. Effective strategies for enhancing algae-based wastewater treatment included cell mass recycling and adjusting dilution rates based on light availability.
BIORESOURCE TECHNOLOGY
(2024)
