SIRT1 Protects Against Oxidative Stress-Induced Endothelial Progenitor Cells Apoptosis by Inhibiting FOXO3a via FOXO3a Ubiquitination and Degradation

Salvianolic acid B protects human endothelial progenitor cells against oxidative stress-mediated dysfunction by modulating Akt/mTOR/4EBP1, p38 MAPK/ATF2, and ERK1/2 signaling pathways

(2014) Yubo Tang et al.   BIOCHEMICAL PHARMACOLOGY

SIRT1 inhibits TNF-α-induced apoptosis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1

(2013) Weirong Wang et al.   APOPTOSIS

Mechanisms underlying protective effects of trimetazidine on endothelial progenitor cells biological functions against H2O2-induced injury: Involvement of antioxidation and Akt/eNOS signaling pathways

(2013) Qinqin Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cytoprotective effect of dieckol on human endothelial progenitor cells (hEPCs) from oxidative stress-induced apoptosis

(2013) S. H. Lee et al.   FREE RADICAL RESEARCH

MicroRNA-16 affects key functions of human endothelial progenitor cells

(2013) Emeline Goretti et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hydrogen peroxide induced impairment of endothelial progenitor cell viability is mediated through a FoxO3a dependant mechanism

(2013) Fei Wang et al.   MICROVASCULAR RESEARCH

Delivery of Therapeutic AGT shRNA by PEG-Bu for Hypertension Therapy

(2013) Yu-Qiang Wang et al.   PLoS One

SIRT1 Regulation Modulates Stroke Outcome

(2013) Valérie Petegnief et al.   Translational Stroke Research

Aberrant Cytoplasm Localization and Protein Stability of SIRT1 is Regulated by PI3K/IGF-1R Signaling in Human Cancer Cells

(2012) Vanessa Byles et al.   International Journal of Biological Sciences

MicroRNA 107 Partly Inhibits Endothelial Progenitor Cells Differentiation via HIF-1β

(2012) Shu Meng et al.   PLoS One

Rationale and design of the Transendocardial Injection of Autologous Human Cells (bone marrow or mesenchymal) in Chronic Ischemic Left Ventricular Dysfunction and Heart Failure Secondary to Myocardial Infarction (TAC-HFT) trial: A randomized, double-blind, placebo-controlled study of safety and efficacy

(2011) Barry Trachtenberg et al.   AMERICAN HEART JOURNAL

Regulation of FOXO protein stability via ubiquitination and proteasome degradation

(2011) Haojie Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5-year results suggest long-term safety and efficacy

(2011) David M. Leistner et al.   Clinical Research in Cardiology

A pathway from JNK through decreased ERK and Akt activities for FOXO3a nuclear translocation in response to UV irradiation

(2011) Xianwang Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation

(2011) F Wang et al.   ONCOGENE

Aging and disease: connections to sirtuins

(2010) Gizem Donmez et al.   AGING CELL

Regulation of SIRT1 in cellular functions: Role of polyphenols

(2010) Sangwoon Chung et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Paracrine factors secreted by endothelial progenitor cells prevent oxidative stress-induced apoptosis of mature endothelial cells

(2010) Zijiang Yang et al.   ATHEROSCLEROSIS

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

(2008) Kazuhiro Hasegawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vascular repair by endothelial progenitor cells

(2008) A. Zampetaki et al.   CARDIOVASCULAR RESEARCH

Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

(2008) Q.-j. Zhang et al.   CARDIOVASCULAR RESEARCH

Transcriptional Regulation of Bim by FOXO3a and Akt Mediates Scleroderma Serum–Induced Apoptosis in Endothelial Progenitor Cells

(2008) Shoukang Zhu et al.   CIRCULATION

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY

Structure/function relationships underlying regulation of FOXO transcription factors

(2008) T Obsil et al.   ONCOGENE

The FoxO code

(2008) D R Calnan et al.   ONCOGENE