CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells

Cell cycle progression in response to oxygen levels

(2014) Brian Ortmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase

(2014) X. Zheng et al.   GENES & DEVELOPMENT

PHD3-SUMO conjugation represses HIF1 transcriptional activity independently of PHD3 catalytic activity

(2014) A. Nunez-O'Mara et al.   JOURNAL OF CELL SCIENCE

The Cep192-Organized Aurora A-Plk1 Cascade Is Essential for Centrosome Cycle and Bipolar Spindle Assembly

(2014) Vladimir Joukov et al.   MOLECULAR CELL

PHD1 Links Cell-Cycle Progression to Oxygen Sensing through Hydroxylation of the Centrosomal Protein Cep192

(2013) Sandra C. Moser et al.   DEVELOPMENTAL CELL

Prolyl Hydroxylase Domain Protein 2 (PHD2) Binds a Pro-Xaa-Leu-Glu Motif, Linking It to the Heat Shock Protein 90 Pathway

(2013) Daisheng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Characterization of FMN2, a Regulator of the Cyclin-Dependent Kinase Inhibitor p21

(2013) Kayo Yamada et al.   MOLECULAR CELL

A Nontranscriptional Role for HIF-1  as a Direct Inhibitor of DNA Replication

(2013) M. E. Hubbi et al.   Science Signaling

PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response

(2012) Liang Xie et al.   JOURNAL OF CLINICAL INVESTIGATION

Toward a Comprehensive Characterization of a Human Cancer Cell Phosphoproteome

(2012) Houjiang Zhou et al.   JOURNAL OF PROTEOME RESEARCH

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

(2012) R V Durán et al.   ONCOGENE

Stabilization of HIF-2α through redox regulation of mTORC2 activation and initiation of mRNA translation

(2012) B K Nayak et al.   ONCOGENE

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration

(2012) M. K. Diril et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH

(2011) Andrew Melvin et al.   MOLECULAR BIOLOGY OF THE CELL

Evolutionary Conserved Regulation of HIF-1β by NF-κB

(2011) Patrick van Uden et al.   PLoS Genetics

IKK and NF-κB-mediated regulation of Claspin impacts on ATR checkpoint function

(2010) Niall Steven Kenneth et al.   EMBO JOURNAL

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38

(2009) Sandra Barth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of gene expression by hypoxia

(2008) Niall Steven Kenneth et al.   BIOCHEMICAL JOURNAL

Regulation of hypoxia-inducible factor-1α by NF-κB

(2008) Patrick van Uden et al.   BIOCHEMICAL JOURNAL

Role and regulation of prolyl hydroxylase domain proteins

(2008) G-H Fong et al.   CELL DEATH AND DIFFERENTIATION

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Expression, Purification and Characterization of Human PHD1 in Escherichia coli

(2008) X. Y. Li et al.   JOURNAL OF BIOCHEMISTRY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

(2007) K. Takeda et al.   BLOOD