TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules

Folding of influenza virus hemagglutinin in insect cells is fast and efficient

(2015) Xin Li et al.   JOURNAL OF BIOTECHNOLOGY

Where is mTOR and what is it doing there?

(2014) Charles Betz et al.   JOURNAL OF CELL BIOLOGY

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21

(2014) M. Cornu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells

(2013) Kathrin Thedieck et al.   CELL

Dual Specificity Kinase DYRK3 Couples Stress Granule Condensation/Dissolution to mTORC1 Signaling

(2013) Frank Wippich et al.   CELL

mRNA cycles through hypoxia-induced stress granules in live Drosophila embryonic muscles

(2013) Annelies M.A. van der Laan et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress

(2013) Reddy Ranjith K. Sama et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inactivation of the mTORC1-Eukaryotic Translation Initiation Factor 4E Pathway Alters Stress Granule Formation

(2013) M.-J. Fournier et al.   MOLECULAR AND CELLULAR BIOLOGY

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

Characterization of Fragile X Mental Retardation Protein Recruitment and Dynamics in Drosophila Stress Granules

(2013) Cristina Gareau et al.   PLoS One

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

LST8 Regulates Cell Growth via Target-of-Rapamycin Complex 2 (TORC2)

(2012) T. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Transient Sequestration of TORC1 into Stress Granules during Heat Stress

(2012) Terunao Takahara et al.   MOLECULAR CELL

Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules

(2012) Ken Fujimura et al.   NUCLEIC ACIDS RESEARCH

The evolution of the TOR pathway and its role in cancer

(2012) E M Beauchamp et al.   ONCOGENE

Activation of mTORC2 by Association with the Ribosome

(2011) Vittoria Zinzalla et al.   CELL

mTOR complex 2 signaling and functions

(2011) Won Jun Oh et al.   CELL CYCLE

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

(2011) T. Glatter et al.   Molecular Systems Biology

Identification of importin α1 as a novel constituent of RNA stress granules

(2010) Ken Fujimura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control

(2010) Kyoko Ikeda et al.   CELL CYCLE

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

(2010) Won Jun Oh et al.   EMBO JOURNAL

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes

(2010) H. Takai et al.   GENES & DEVELOPMENT

mTORC1 controls fasting-induced ketogenesis and its modulation by ageing

(2010) Shomit Sengupta et al.   NATURE

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vgl1, a multi-KH domain protein, is a novel component of the fission yeast stress granules required for cell survival under thermal stress

(2010) W.-L. Wen et al.   NUCLEIC ACIDS RESEARCH

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TOR signaling in invertebrates

(2009) Alexandre Soulard et al.   CURRENT OPINION IN CELL BIOLOGY

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

(2009) A. A. Soukas et al.   GENES & DEVELOPMENT

TOR Complex 2 Controls Gene Silencing, Telomere Length Maintenance, and Survival under DNA-Damaging Conditions

(2009) M. Schonbrun et al.   MOLECULAR AND CELLULAR BIOLOGY

Metazoan stress granule assembly is mediated by P-eIF2 -dependent and -independent mechanisms

(2009) N. G. Farny et al.   RNA

Hsp70 associates with Rictor and is required for mTORC2 formation and activity

(2008) Jheralyn Martin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

(2008) Tsuneo Ikenoue et al.   EMBO JOURNAL

Codependent Functions of RSK2 and the Apoptosis-Promoting Factor TIA-1 in Stress Granule Assembly and Cell Survival

(2008) T.S. Karin Eisinger-Mathason et al.   MOLECULAR CELL

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

(2008) Kyoko Arimoto et al.   NATURE CELL BIOLOGY

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES