LTP-triggered cholesterol redistribution activates Cdc42 and drives AMPA receptor synaptic delivery

Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

(2014) M. G. Martin et al.   EMBO Molecular Medicine

PTEN counteracts PIP3 upregulation in spines during NMDA-receptor-dependent long-term depression

(2014) K. L. Arendt et al.   JOURNAL OF CELL SCIENCE

Different oxysterols have opposing actions at N-methyl-d-aspartate receptors

(2014) Andrew J. Linsenbardt et al.   NEUROPHARMACOLOGY

Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

(2014) Il Hwan Kim et al.   eLife

AMPARs and Synaptic Plasticity: The Last 25 Years

(2013) Richard L. Huganir et al.   NEURON

Distinct lipid compositions of two types of human prostasomes

(2013) Jos F. Brouwers et al.   PROTEOMICS

Reduction of the Cholesterol Sensor SCAP in the Brains of Mice Causes Impaired Synaptic Transmission and Altered Cognitive Function

(2013) Ryo Suzuki et al.   PLOS BIOLOGY

The link between altered cholesterol metabolism and Alzheimer's disease

(2012) Paola Gamba et al.   Annals of the New York Academy of Sciences

Cholesterol loss during glutamate-mediated excitotoxicity

(2012) Alejandro O Sodero et al.   EMBO JOURNAL

Regulation of presynaptic strength by controlling Ca2+ channel mobility: effects of cholesterol depletion on release at the cone ribbon synapse

(2012) Aaron J. Mercer et al.   JOURNAL OF NEUROPHYSIOLOGY

A Role for Sphingomyelin-Rich Lipid Domains in the Accumulation of Phosphatidylinositol-4,5-Bisphosphate to the Cleavage Furrow during Cytokinesis

(2012) M. Abe et al.   MOLECULAR AND CELLULAR BIOLOGY

LTP requires a reserve pool of glutamate receptors independent of subunit type

(2012) Adam J. Granger et al.   NATURE

Mass Spectrometric Detection of Cholesterol Oxidation in Bovine Sperm1

(2011) Jos F. Brouwers et al.   BIOLOGY OF REPRODUCTION

The Small GTPase Cdc42 Interacts with Niemann-Pick C1-like 1 (NPC1L1) and Controls Its Movement from Endocytic Recycling Compartment to Plasma Membrane in a Cholesterol-dependent Manner

(2011) Chang Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of tyrosine kinase B activity by the Cyp46/cholesterol loss pathway in mature hippocampal neurons: relevance for neuronal survival under stress and in aging

(2011) Alejandro O. Sodero et al.   JOURNAL OF NEUROCHEMISTRY

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Lipid changes in the aged brain: Effect on synaptic function and neuronal survival

(2011) María Dolores Ledesma et al.   PROGRESS IN LIPID RESEARCH

Lipids and Cholesterol as Regulators of Traffic in the Endomembrane System

(2010) Jennifer Lippincott-Schwartz et al.   Annual Review of Biophysics

The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis

(2010) Alejo E. Rodriguez-Fraticelli et al.   JOURNAL OF CELL BIOLOGY

Cholesterol reduction impairs exocytosis of synaptic vesicles

(2010) A. Linetti et al.   JOURNAL OF CELL SCIENCE

Cholesterol Defect Is Marked across Multiple Rodent Models of Huntington's Disease and Is Manifest in Astrocytes

(2010) M. Valenza et al.   JOURNAL OF NEUROSCIENCE

Cholesterol-Dependent Kinase Activity Regulates Transmitter Release from Cerebellar Synapses

(2010) A. J. Smith et al.   JOURNAL OF NEUROSCIENCE

SYMPOSIUM REVIEW: Lipid microdomains and the regulation of ion channel function

(2010) Caroline Dart   JOURNAL OF PHYSIOLOGY-LONDON

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cellular stress from excitatory neurotransmission contributes to cholesterol loss in hippocampal neurons aging in vitro

(2010) Alejandro O. Sodero et al.   NEUROBIOLOGY OF AGING

Control of the Postsynaptic Membrane Viscosity

(2009) M. Renner et al.   JOURNAL OF NEUROSCIENCE

Cyp46-mediated cholesterol loss promotes survival in stressed hippocampal neurons

(2009) Mauricio G. Martin et al.   NEUROBIOLOGY OF AGING

Simvastatin enhances hippocampal long-term potentiation in C57BL/6 mice

(2009) R.A. Mans et al.   NEUROSCIENCE

Cholesterol depletion inhibits synaptic transmission and synaptic plasticity in rat hippocampus

(2008) C. Frank et al.   EXPERIMENTAL NEUROLOGY

Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells

(2008) David L. Marks et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Regulation of AMPA receptor localization in lipid rafts

(2008) Qingming Hou et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cholesterol Loss Enhances TrkB Signaling in Hippocampal Neurons Aging in Vitro

(2008) Mauricio G. Martin et al.   MOLECULAR BIOLOGY OF THE CELL

BODIPY-Cholesterol: A New Tool to Visualize Sterol Trafficking in Living Cells and Organisms

(2008) Maarit Hölttä-Vuori et al.   TRAFFIC