Strain-dependent oxidant release in articular cartilage originates from mitochondria

Mechanical stress and ATP synthesis are coupled by mitochondrial oxidants in articular cartilage

(2012) Katherine J. Wolff et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mitochondrial electron transport and glycolysis are coupled in articular cartilage

(2012) J.A. Martin et al.   OSTEOARTHRITIS AND CARTILAGE

Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes

(2011) Rasheed Ahmad et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Towards the mechanisms involved in the antioxidant action of MnIII [meso-tetrakis(4-N-methyl pyridinium) porphyrin] in mitochondria

(2011) Juliana C. Araujo-Chaves et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Cytoskeletal dissolution blocks oxidant release and cell death in injured cartilage

(2011) Ellen Sauter et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The role of mitochondria in osteoarthritis

(2011) Francisco J. Blanco et al.   Nature Reviews Rheumatology

Repeated measurement of mechanical properties in viable osteochondral explants following a single blunt impact injury

(2011) P S Ramakrishnan et al.   PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE

Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism

(2010) Julia Strathmann et al.   FASEB JOURNAL

Oxidant conditioning protects cartilage from mechanically induced damage

(2010) Prem Ramakrishnan et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

In-vivo time-dependent articular cartilage contact behavior of the tibiofemoral joint

(2010) A. Hosseini et al.   OSTEOARTHRITIS AND CARTILAGE

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

N-Acetylcysteine Inhibits Post-Impact Chondrocyte Death in Osteochondral Explants

(2009) James A Martin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Mechanical Injury and Cytokines Cause Loss of Cartilage Integrity and Upregulate Proteins Associated with Catabolism, Immunity, Inflammation, and Repair

(2009) Anna L. Stevens et al.   MOLECULAR & CELLULAR PROTEOMICS

Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes

(2008) Berta Cillero-Pastor et al.   ARTHRITIS AND RHEUMATISM

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

Mapping the depth dependence of shear properties in articular cartilage

(2008) Mark R. Buckley et al.   JOURNAL OF BIOMECHANICS

In vivo cartilage contact deformation in the healthy human tibiofemoral joint

(2008) J. T. Bingham et al.   RHEUMATOLOGY