Article
Chemistry, Physical
V. S. S. L. Prasad Talluri, Botagoz Mutaliyeva, Altynay Sharipova, Vamseekrishna Ulaganathan, Sri Santhi Lanka, Saule Aidarova, Aliya Suigenbayeva, Aiym Tleuova
Summary: L-asparaginase is an important enzyme used in therapeutic applications, and immobilization can minimize its side effects and improve its performance.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Huijuan Jing, Xiaojing Du, Ling Mo, Hongxin Wang
Summary: Carboxymethyl chitosan (CMCS)-based self-coacervates have shown great potential in drug oral delivery due to their pH-responsive properties and stability in a wide pH range. These self-coacervates also exhibit excellent encapsulation efficiency and loading capacity for lactoferrin (LF) encapsulation, protecting LF from hydrolysis during simulated gastric digestion. Overall, CMCS self-coacervation can be utilized as a pH-responsive encapsulation and delivery strategy.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Chemistry, Applied
Zohreh Mohammadi, Maryam Eini, Ali Rastegari, Morteza Rafiee Tehrani
Summary: Numerous studies have demonstrated the significant role of biomolecules in treating diseases, but the challenge lies in designing efficient delivery systems. Chitosan, a unique biopolymer with special properties, has been widely utilized for biomolecule delivery, with research groups focusing on its versatile application.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Maryam Sadat Mirmohammad Meiguni, Maryam Salami, Karamatollah Rezaei, Mohammad Amin Aliyari, Seyed-Behnam Ghaffari, Zahra Emam-Djomeh, John F. Kennedy, Atiye Ghasemi
Summary: The present study developed a novel complex coacervate based on succinyl mung bean protein and gum arabic to encapsulate curcumin. The encapsulation of curcumin in the complex coacervate hydrophobic core was successful, and the succinylation process caused minor changes in SMBP conformation. The c-SMBP/GA showed enhanced dispersity characteristics and release behavior, making it a promising tool for encapsulating curcumin in food matrices.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Srisan Phupaboon, Maharach Matra, Ronnachai Prommachart, Pajaree Totakul, Chanadol Supapong, Metha Wanapat
Summary: The objective of this research was to study the bioactive compounds of herbal plant leaves through microencapsulation technique and explore their potential application as feed additives. Three herbal plants, namely Cannabis sativa L., Cannabis indica L., and Mitragyna speiosa K., were investigated using different methods to extract their bioactive compounds. Microwave extraction yielded higher total polyphenolic and flavonoid contents and stronger antioxidant capacity compared to maceration extraction. The extracted compounds were then encapsulated with chitosan through spray-drying, resulting in improved recovery with high encapsulation efficiency.
Article
Pharmacology & Pharmacy
Pavel Khramtsov, Oksana Burdina, Sergey Lazarev, Anastasia Novokshonova, Maria Bochkova, Valeria Timganova, Dmitriy Kiselkov, Artem Minin, Svetlana Zamorina, Mikhail Rayev
Summary: The modified one-step desolvation method allows for quick, simple, and reproducible synthesis of gelatin nanoparticles with high yields of 62-82%. The nanoparticles have good colloidal stability, narrow size distribution, and are non-toxic to human immune cells, showing great potential for various applications in drug delivery and biotechnology.
Article
Chemistry, Physical
Md. Abdur Razzak, Seong-Jun Cho
Summary: As people's awareness of the health benefits of foods and their nutritional benefits for preventing diseases and promoting health increases, the demand for functional foods rich in proteins, fiber, and bioactives like capsaicin (CAP) is constantly rising. This study demonstrated that the electrostatic complexes developed by cricket protein isolate (CPI) and alginate (AL) can effectively encapsulate CAP, improving its solubility and protecting it at acidic pHs. The findings contribute to the growing body of knowledge that validates protein-polysaccharide complexation as a promising strategy for developing edible delivery systems.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Food Science & Technology
Zedong Shi, Yaping Jiang, Yingjie Sun, Dedong Min, Fujun Li, Xiaoan Li, Xinhua Zhang
Summary: Oregano essential oil nanocapsules (OEO-NPs) prepared via complex coacervation method exhibited higher thermal stability and slow-release performance. During the shelf life of apricot fruit, 4% OEO-NPs showed better fungistatic effect and reduced decay rate. OEO-NPs provided a new idea for the development of green and slow-release fungistatic agent.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Article
Engineering, Chemical
Loleny Tavares, Lucia Santos, Caciano Pelayo Zapata Norena
Summary: Garlic essential oil was microencapsulated using molecular inclusion and complex coacervation methods, resulting in dispersions with different physical properties. Incorporation of the oil into wall systems improved the properties of the microparticles, with higher entrapment yield and lower water activity.
Article
Acoustics
Touseef Ahmed Wani, F. A. Masoodi, Rehana Akhter, Towseef Akram, Adil Gani, Nadeem Shabir
Summary: This research investigated the production of chitosan nanocapsules for encapsulating hydroxytyrosol. The resulting nanocapsules exhibited favorable packaging characteristics and encapsulation efficiency, and showed superior antioxidant and antiproliferative properties compared to free hydroxytyrosol.
ULTRASONICS SONOCHEMISTRY
(2022)
Article
Chemistry, Applied
Kai Chen, Min Zhang, Arun S. Mujumdar, Haixiang Wang
Summary: In this study, eugenol encapsulated multi-core microcapsules were successfully developed using quinoa protein and gum Arabic via complex coacervation, which exhibited good thermal stability and release properties. The microcapsules effectively prolonged the shelf life of minced pork, showing promising potential in meat preservation.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Multidisciplinary
Amy Wilson, Ekanem E. Ekanem, Davide Mattia, Karen J. Edler, Janet L. Scott
Summary: This study reports the continuous fabrication of stable microcapsules using renewable, biodegradable biopolymer wall materials keratin and chitosan via membrane emulsification for the first time. The microcapsules, with a core-shell structure formed through interfacial complexation of keratin and chitosan, showed enhanced stability and release efficiency, potentially for applications in skin pH formulas for oil protection.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Food Science & Technology
Lei Wang, Ying Zhang, Jiang -Fen Chen, Yan-Yu Luo, Chun-Xia Zou, Li-Kang Qin, Yu-Long Jia
Summary: This study used whey protein and three wall materials to prepare microcapsules and solve the problem of lipid oxidation instability. The combination of whey protein and chitosan was found to be the best embedding method. The microcapsules showed good thermal stability and could delay the digestion of Camellia oleifera oil in gastric juice, providing a new application for Camellia oleifera seed oil in various fields.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Polymer Science
Neeraj P. P. Pasarkar, Mukesh Yadav, Prakash. A. Mahanwar
Summary: Thermal energy storage is an effective method for conserving energy and improving efficiency and reliability. The use of microcapsules in the encapsulation of phase change materials (PCMs) enhances their mechanical and thermal performance, preventing leakage and reactivity with the environment. A comprehensive evaluation of PCM microcapsules is presented in this review, covering their classification, shell materials, encapsulation methods, characterization, and thermal applications.
JOURNAL OF POLYMER RESEARCH
(2023)
Article
Polymer Science
Galo Cardenas-Trivino, Sebastian Monsalve-Rozas, Luis Vergara-Gonzalez
Summary: Microcapsules based on chitosan and including nano-magnetite and erlotinib were synthesized and characterized by SEM, FT-IR, and TGA. The encapsulation percentage was determined, showing bacteriostatic properties. The HPLC analysis indicated a 52% encapsulation rate, and the encapsulated drug exhibited lower effectiveness and toxicity in vitro studies compared to the non-encapsulated drug.
Article
Mechanics
Suresh S. Kumar, Arjun Shyam Sundar, R. Deepak
Summary: The stress intensity factor (SIF) of opposite surface cracks in an un-notched round bar under tension and combined load conditions was determined using a numerical method. The influence of loading modes on SIF was investigated, considering different crack depth ratios and crack aspect ratios. It was found that the SIF distribution changed as the crack depth ratio increased under pure tensile loading, and nonuniform and asymmetric SIF spread was observed when torque was applied. The effect of mode-II and mode-III fractures was more pronounced under combined loading.
MECHANICS BASED DESIGN OF STRUCTURES AND MACHINES
(2023)
Article
Mechanics
U. Magarajan, S. Suresh Kumar
Summary: This paper investigates the ballistic performance of AA6061-B4C surface composite targets fabricated by the Friction Stir Processing (FSP) technique. The paper is divided into two stages: stage I focuses on identifying suitable process parameters, while stage II conducts ballistic experiments for single and multiple hit conditions. The results show that FSPed AA6061-B4C targets exhibit better ballistic performance compared to BM targets.
MECHANICS BASED DESIGN OF STRUCTURES AND MACHINES
(2023)
Article
Otorhinolaryngology
Eli Stein, Alexander L. Schneider, Regan Harmon, Samuel D. Racette, Abhita T. Reddy, Caroline P. E. Price, Julia H. Huang, Atsushi Kato, Stephanie Shintani-Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan
Summary: Discharge or edema after endoscopic sinus surgery (ESS) in the absence of polyps is associated with higher patient-reported outcome severity and is more strongly associated with type 1 or 3 inflammation.
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY
(2023)
Review
Crystallography
Madunuri Chandra Sekhar, Eshwarappa Veena, Nagasamudram Suresh Kumar, Kadiyala Chandra Babu Naidu, Allam Mallikarjuna, Dudekula Baba Basha
Summary: This paper provides a review on recent advancements in piezoelectric materials and their applications in various fields such as catalysis, energy harvesting, and sensors. It also discusses the limitations of piezoelectric materials.
CRYSTAL RESEARCH AND TECHNOLOGY
(2023)
Article
Clinical Neurology
Sureshkumar Kamalakannan, Vijay Karunakaran, Ashwin Balaji, Aadi Sai Vijaykaran, Sivakumar Ramachandran, Ramakumar Nagarajan
Summary: ReWin, a digital therapeutics platform for stroke rehabilitation, was found to be feasible and acceptable in an Indian context through two phases of pilot testing. About 76% of participants used ReWin for more than half of the intervention period, and 90% of stroke care providers and 60% of stroke survivors and caregivers found the content of ReWin to be very relevant. Based on overall credibility, usability, and user-friendliness, 40% of stroke survivors and caregivers as well as 90% of stroke care providers rated the ReWin intervention as excellent.
FRONTIERS IN NEUROLOGY
(2023)
Review
Public, Environmental & Occupational Health
Tiago S. Jesus, Sureshkumar Kamalakannan, Sutanuka Bhattacharjya, Janet Prvu Bettger, Karen Jacobs, Helen Hoenig
Summary: This study describes a protocol for a mixed-methods systematic review aimed at identifying the usage and implementation of telerehabilitation in the delivery of rehabilitation services. The review will search six databases for relevant literature and use a framework synthesis approach to analyze the data. The results can inform future implementation efforts.
WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION
(2023)
Article
Health Policy & Services
Tiago S. Jesus, Karthik Mani, Sutanuka Bhattacharjya, Sureshkumar Kamalakannan, Claudia von Zweck, Ritchard Ledgerd
Summary: Occupational therapy workforce needs global strategy for strengthening, as there is a lack of research and resources, as well as various challenges and threats that need to be addressed.
INTERNATIONAL JOURNAL OF HEALTH PLANNING AND MANAGEMENT
(2023)
Review
Rehabilitation
Tiago S. Jesus, Karthik Mani, Claudia von Zweck, Sutanuka Bhattacharjya, Sureshkumar Kamalakannan, Ritchard Ledgerd
Summary: To fulfill their societal role, occupational therapists need to exist in sufficient supply, be equitably distributed, and meet competency standards. However, worldwide occupational therapy workforce research is scant and inequitably distributed, uses suboptimal methods, and is underfunded. Concerted efforts are needed to strengthen occupational therapy workforce research.
AMERICAN JOURNAL OF OCCUPATIONAL THERAPY
(2023)
Article
Education, Special
Samantha R. R. Goldman, Adam Carreon, Sean J. J. Smith, Jennifer Kurth
Summary: Many students struggle with written expression, but technology supports like speech-to-text, text-to-speech, and predictive text can help mitigate barriers. However, challenges remain in selecting the right tools, training educators and students on how to use them, and overcoming the time investment required.
JOURNAL OF SPECIAL EDUCATION TECHNOLOGY
(2023)
Article
Chemistry, Physical
G. Velmurugan, Jasgurpreet Singh Chohan, S. A. Muhammed Abraar, R. Sathish, S. Senthil Murugan, M. Nagaraj, S. Suresh Kumar, V. Siva Shankar, D. Elil Raja
Summary: Natural fibre-based nanocomposite is a revolutionary material with excellent strength-to-weight ratio and lightweight, widely used in construction and dynamic industries. This study investigated the effects of silicon nanoparticles on the moisture absorption, mechanical properties, flammability, and dynamic mechanical behavior of PP/jute fibre composites. The results showed that increasing the weight of SiO2 nanoparticles improved the modulus of elasticity, tension strength, and elongation at breakage of the composites. The addition of SiO2 nanoparticles also enhanced the fire characteristics and dynamic mechanical behavior. However, the dispersion of SiO2 nanoparticles in the composites needs to be improved.
Article
Chemistry, Multidisciplinary
Rajapriya Pandy, Senthuran Suresh Kumar, Perumal Suresh, Jamespandi Annaraj, Mohan Pandi, Shanmugaiah Vellasamy, Suresh Sagadevan
Summary: In this study, seven endophytic fungi from Millingtonia hortensis were screened and five of them were found to produce taxol. The fungal taxol showed significant antibacterial and antifungal activities against human and fungal pathogens. Moreover, it exhibited cytotoxic effects against human liver cancer cells, suggesting its potential as an anticancer agent.
Meeting Abstract
Surgery
Joohyun Kim, Suresh Kumar, Yongqiang Yang, Seung-Keun Hong, Johnny Hong
AMERICAN JOURNAL OF TRANSPLANTATION
(2023)
Review
Clinical Neurology
Dimple Dawar, Sureshkumar Kamalakannan, Nistara S. Chawla, Jibil T. Mathew, Esha Mehmood, Unnati Bhatnagar, Jeyaraj Durai Pandian
Summary: The study reviewed the intervention and outcome measures for post-stroke cognitive impairments. It found that there is diversity and heterogeneity in the interventions and measures used. While technology is replacing conventional approaches, there is limited data on scalable solutions. Future research is needed for evidence-based assessment and management of cognitive impairments in post-stroke rehabilitation.
ANNALS OF INDIAN ACADEMY OF NEUROLOGY
(2023)
Article
Chemistry, Applied
Jhilmil Swapnalin, Suresh N. Kumar, Kadiyala Chandra Babu Naidu, Prasun Banerjee
Summary: This review investigates the applications of Electron paramagnetic resonance (EPR) in biological systems, discussing its latest developments in areas such as photosynthesis, metalloproteins, radical enzymes, and phospholipid membranes. By utilizing EPR spectroscopy, the dynamics and structure of biological systems can be calculated, providing a better understanding of the radical state of proteins compared to XRD or NMR techniques.
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY
(2023)
Review
Rehabilitation
Sureshkumar Kamalakannan, Paula W. Rushton, Ed Giesbrecht, David F. Rusaw, Selsabil-A Bouziane, Melodie Nadeau, Jennifer McKee, Rosemary J. Gowran, R. Lee Kirby, Jessica P. Pedersen, Tomasz Tasiemski, Yohali Burrola-Mendez, Marco Tofanin, Mary Goldberg, Jon Pearlman
Summary: This planned scoping review aims to examine and synthesize the global literature on wheelchair service provision education for healthcare professional students, healthcare personnel and educators. The review will provide insights into the organization, content, evaluation, and integration models of wheelchair service provision education on a global scale.
DISABILITY AND REHABILITATION-ASSISTIVE TECHNOLOGY
(2023)
Article
Engineering, Biomedical
Lin-Lin Luo, Jie Xu, Bing-Qiao Wang, Chen Chen, Xi Chen, Qiu-Mei Hu, Yu-Qiu Wang, Wan-Yun Zhang, Wan-Xiang Jiang, Xin-Ting Li, Hu Zhou, Xiao Xiao, Kai Zhao, Sen Lin
Summary: A novel AAV serotype, AAVYC5, introduced in this study, showed more efficient transduction into multiple retinal layers compared to AAV2, and enabled successful delivery of anti-angiogenic molecules in mice and non-human primates.