Article
Chemistry, Multidisciplinary
Komal Raje, Keisuke Ohashi, Satoshi Fujita
Summary: A new method using 3D printing and electrospinning was developed to create intricate 3D microfibrous structures with high elasticity and adaptability. This method has the potential for applications in regenerative medicine for crafting artificial organs and cell culture scaffolds.
Article
Chemistry, Analytical
Tina Karimian, Roland Hager, Andreas Karner, Julian Weghuber, Peter Lanzerstorfer
Summary: This article introduces a simplified activation procedure for depositing biomolecule micropatterns on untreated solid substrates, allowing for direct microcontact printing and strong protein attachment via avidity binding. The specificity and suitability of this method have been demonstrated in proof-of-concept experiments, enhancing the accessibility of protein micropatterning for cell biological research.
Article
Nanoscience & Nanotechnology
Daniel W. Simmons, David R. Schuftan, Ghiska Ramahdita, Nathaniel Huebsch
Summary: Tissue-engineered in vitro models are important tools in biomedical research. However, controlling the geometry of microscale tissues is challenging. In this study, a double molding approach was developed to replicate high-resolution stereolithographic prints into PDMS elastomer, facilitating rapid design iterations and parallelized sample production. Additionally, this method minimizes the transfer of toxic materials from the original 3D print into the PDMS replica, enhancing its use for biological applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Optics
Jean-Loup Skora, Olivier Gaiffe, Sylwester Bargiel, Jean-Marc Cote, Laurent Tavernier, Michel de Labachelerie, Nicolas Passilly
Summary: In this study, micro-axicons made of glass were fabricated using laser-assisted wet etching and laser polishing techniques. The results showed that a quasi-Bessel beam with a stable diameter could be generated near the tip of the micro-axicon.
Article
Chemistry, Physical
Jaebum Sung, Hongyun So
Summary: This study demonstrates the use of 3D printing to create a variety of microgrid patterned surfaces, which can significantly reduce the adhesive forces of polymer surfaces by altering the angles and printing resolution.
SURFACES AND INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Sayli Jambhulkar, Dharneedar Ravichandran, Varunkumar Thippanna, Dhanush Patil, Kenan Song
Summary: This study focuses on a non-conventional, mask-free micropatterning technique that combines bottom-up 3D printing and top-down wet etching. The unique 3D printing process enables micro-confinement of sacrificial ink, which can be selectively dissolved through wet etching. This hybrid approach shows potential in various applications such as nanoparticle assembly, drug delivery, optical lenses, intelligent microbots, and morphing objects.
ADVANCED COMPOSITES AND HYBRID MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Korinde A. Van den Heuvel, Alberto Berardi, Lisa B. Buijvoets, Bastiaan H. J. Dickhoff
Summary: The study found that tablets with targeted mechanical and dissolution characteristics could be successfully printed using both research and development (R & D) and good manufacturing practice (GMP) printing equipment. However, the transfer from R & D to GMP printer required adjustment of the print settings, resulting in slightly different product properties.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Physical
Jian Zhang, Wenhua Zhang, Haoxiang Wei, Jiaqi Tang, Deyu Li, Dongyan Xu
Summary: Body heat can be used as a sustainable energy source for wearable and implantable devices. We have developed flexible micro thermoelectric generators (TEGs) with high power density and light weight through pulse electroplating. The optimized flexible micro TEG achieves maximum areal and gravimetric power densities of 14.3 mW cm-2 and 189 mW g-1, respectively, under a temperature difference of 29.9 degrees C. The voltage factor and normalized power to weight ratio of our flexible micro TEG are significantly higher than existing cross-plane flexible TEGs, providing new opportunities for self-powered wearable electronics.
Article
Chemistry, Multidisciplinary
Jiuk Jang, Young-Geun Park, Eunkyung Cha, Sangyoon Ji, Hyunbin Hwang, Gon Guk Kim, Jungho Jin, Jang-Ung Park
Summary: This study introduces a convenient method for transferring perovskite patterns to different surfaces using a removable polymer, enabling integration of perovskite devices. The transfer method allows fabrication of a perovskite image sensor array on soft contact lenses and heterogeneous integration of a perovskite photodetector array with pressure-sensitive silicon transistors, creating a multiplexed sensing platform.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Analytical
Saisneha Koppaka, Kevin Zhang, Myra Kurosu Jalil, Lucas Blauch, Sindy Tang
Summary: This paper discusses the fabrication process of 3D micro-blades for cutting single cells using Nanoscribe technology, and shows that complex micro-blade features can generate different degrees of cell wounding and cell survival rates compared to simple blades fabricated with conventional photolithography.
Article
Engineering, Electrical & Electronic
Dacheng Mao, Zheshun Xiong, Matthew Donnelly, Guangyu Xu
Summary: The study introduced a simple fabrication method for high-density, two-color quantum dot-based micro-LED arrays, which can be used for bi-directional optogenetics at the cellular level. The array featured small-sized light spots with high optical power density, along with low crosstalk and fast response.
IEEE ELECTRON DEVICE LETTERS
(2021)
Article
Clinical Neurology
Stephan N. Schon, Nicolas Skalicky, Neha Sharma, Daniel W. Zumofen, Florian M. Thieringer
Summary: The study demonstrated the feasibility of developing patient-specific implants for cranioplasty using a novel 3D-printer-assisted method. The workflow for implant production was efficient, resulting in cosmetically appealing results with well-fitting implants. However, complications were observed in a portion of patients, highlighting the need for further improvement in the procedure.
WORLD NEUROSURGERY
(2021)
Article
Chemistry, Physical
Jingjiang Qiu, Junfu Li, Zhongwei Guo, Yudong Zhang, Bangbang Nie, Guochen Qi, Xiang Zhang, Jiong Zhang, Ronghan Wei
Summary: This study optimized the use of DLP technology for fast manufacturing of microfluidic chips, overcoming the challenges of time and cost associated with traditional fabrication methods. By combining open-channel design with transparent adhesive tape sealing, complex microstructures can be rapidly printed.
Article
Engineering, Biomedical
Laszlo Jaksa, Dieter Pahr, Gernot Kronreif, Andrea Lorenz
Summary: Anatomical models are essential for medical education and pre-operative planning, and experimental models made with additive manufacturing have improved realism. This study proposes multi-material structuring for reproducing mechanical properties of soft tissues, achieved through a 3D printer designed for printing objects with various geometric features.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2021)
Article
Chemistry, Multidisciplinary
Wanlu Li, Mian Wang, Luis Santiago Mille, Juan Antonio Robledo Lara, Valentin Huerta, Tlalli Uribe Velazquez, Feng Cheng, Hongbin Li, Jiaxing Gong, Terry Ching, Caroline A. Murphy, Ami Lesha, Shabir Hassan, Tim B. F. Woodfield, Khoon S. Lim, Yu Shrike Zhang
Summary: A portable 3D Digital Light Processing (DLP) printer has been developed using a smartphone-powered projector and custom-written app, enabling the printing of detailed structures and tissue analogs. The printer allows for fabrication of medical implants and cell-laden tissues on-site, marking a milestone in mobile-health technologies. The integration of a 3D scanning smartphone app further enhances the printer's capabilities for various applications in resource-limited and point-of-care settings.
ADVANCED MATERIALS
(2021)
Review
Engineering, Biomedical
Azadeh Seidi, Murugan Ramalingam, Imen Elloumi-Hannachi, Serge Ostrovidov, Ali Khademhosseini
ACTA BIOMATERIALIA
(2011)
Article
Engineering, Biomedical
Imen Elloumi Hannachi, Kazuyoshi Itoga, Yoshikazu Kumashiro, Jun Kobayashi, Masayuki Yamato, Teruo Okano
Article
Biotechnology & Applied Microbiology
Elloumi Hannachi Imen, Makiko Nakamura, Masayasu Mie, Eiry Kobatake
JOURNAL OF BIOTECHNOLOGY
(2009)
Review
Engineering, Biomedical
Imen Elloumi Hannachi, Masayuki Yamato, Teruo Okano
Article
Engineering, Biomedical
I Elloumi, R Kobayashi, H Funabashi, M Mie, E Kobatake
Article
Engineering, Biomedical
Lin-Lin Luo, Jie Xu, Bing-Qiao Wang, Chen Chen, Xi Chen, Qiu-Mei Hu, Yu-Qiu Wang, Wan-Yun Zhang, Wan-Xiang Jiang, Xin-Ting Li, Hu Zhou, Xiao Xiao, Kai Zhao, Sen Lin
Summary: A novel AAV serotype, AAVYC5, introduced in this study, showed more efficient transduction into multiple retinal layers compared to AAV2, and enabled successful delivery of anti-angiogenic molecules in mice and non-human primates.
