Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

The HARE-HTH and associated domains

(2012) L. Aravind et al.   CELL CYCLE

Identification of a target cell permissive factor required for contact-dependent growth inhibition (CDI)

(2012) E. J. Diner et al.   GENES & DEVELOPMENT

Identification of novel components of NAD-utilizing metabolic pathways and prediction of their biochemical functions

(2012) Robson Francisco de Souza et al.   Molecular BioSystems

Type VI secretion requires a dynamic contractile phage tail-like structure

(2012) M. Basler et al.   NATURE

A Xanthomonas uridine 5′-monophosphate transferase inhibits plant immune kinases

(2012) Feng Feng et al.   NATURE

An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome

(2012) V. L. Kung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of a caspase-like fold inTannerella forsythiavirulence factor PrtH

(2011) Jimin Pei et al.   CELL CYCLE

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

(2011) Lakshminarayan M. Iyer et al.   CELL CYCLE

The PIDDosome, DNA-damage-induced apoptosis and beyond

(2011) S Janssens et al.   CELL DEATH AND DIFFERENTIATION

Toxins-antitoxins: diversity, evolution and function

(2011) Finbarr Hayes et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane

(2011) Jeong Soon Park et al.   FASEB JOURNAL

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis

(2011) Tse Siang Kang et al.   FEBS Journal

A novel family of toxin/antitoxin proteins inBacillusspecies

(2011) Laura E. Holberger et al.   FEBS LETTERS

Endosymbiotic bacteria associated with nematodes, ticks and amoebae

(2011) Mark Taylor et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Members of the Salivary Gland Surface Protein (SGS) Family Are Major Immunogenic Components of Mosquito Saliva

(2011) Jonas G. King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expansion of Type II CAAX Proteases Reveals Evolutionary Origin of γ-Secretase Subunit APH-1

(2011) Jimin Pei et al.   JOURNAL OF MOLECULAR BIOLOGY

Genetic interaction between Caenorhabditis elegans teneurin ten-1 and prolyl 4-hydroxylase phy-1 and their function in collagen IV–mediated basement membrane integrity during late elongation of the embryo

(2011) Ulrike Topf et al.   MOLECULAR BIOLOGY OF THE CELL

Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin system

(2011) A. Maxwell Burroughs et al.   Molecular BioSystems

Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

(2011) Alexander R. C. Wong et al.   MOLECULAR MICROBIOLOGY

Type VI secretion delivers bacteriolytic effectors to target cells

(2011) Alistair B. Russell et al.   NATURE

BcSpl1, a cerato-platanin family protein, contributes to Botrytis cinerea virulence and elicits the hypersensitive response in the host

(2011) Marcos Frías et al.   NEW PHYTOLOGIST

A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems

(2011) Dapeng Zhang et al.   NUCLEIC ACIDS RESEARCH

Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems

(2011) Lakshminarayan M. Iyer et al.   NUCLEIC ACIDS RESEARCH

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

Phylogenomic Analysis of Odyssella thessalonicensis Fortifies the Common Origin of Rickettsiales, Pelagibacter ubique and Reclimonas americana Mitochondrion

(2011) Kalliopi Georgiades et al.   PLoS One

Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities

(2011) J.-P. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate specificity and mutational analysis of Kluyveromyces lactis  -toxin, a eukaryal tRNA anticodon nuclease

(2011) R. Jain et al.   RNA

Toxin on a stick

(2011) Stephanie K. Aoki et al.   Virulence

Identification of Functional Toxin/Immunity Genes Linked to Contact-Dependent Growth Inhibition (CDI) and Rearrangement Hotspot (Rhs) Systems

(2011) Stephen J. Poole et al.   PLoS Genetics

Bacterial Contact-Dependent Delivery Systems

(2010) Christopher S. Hayes et al.   Annual Review of Genetics

An Rhs-like genetic element is involved in bacteriocin production by Pseudomonas savastanoi pv. savastanoi

(2010) Angelo Sisto et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Toxin–antitoxin systems: why so many, what for?

(2010) Laurence Van Melderen   CURRENT OPINION IN MICROBIOLOGY

Conflicts Targeting Epigenetic Systems and Their Resolution by Cell Death: Novel Concepts for Methyl-Specific and Other Restriction Systems

(2010) K. Ishikawa et al.   DNA RESEARCH

Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily

(2010) Anne-Sophie Delattre et al.   FEBS Journal

Crystal Structure of the Peptidase Domain ofStreptococcusComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway

(2010) Seiji Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Insights into the Role of RNase L in Innate Immunity

(2010) Arindam Chakrabarti et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The SciZ protein anchors the enteroaggregativeEscherichia coliType VI secretion system to the cell wall

(2010) Marie-Stéphanie Aschtgen et al.   MOLECULAR MICROBIOLOGY

Tubules and donuts: a type VI secretion story

(2010) Gabriele Bönemann et al.   MOLECULAR MICROBIOLOGY

A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria

(2010) Stephanie K. Aoki et al.   NATURE

Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3

(2010) C Leong Ng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Origin and evolution of peptide-modifying dioxygenases and identification of the wybutosine hydroxylase/hydroperoxidase

(2010) L. M. Iyer et al.   NUCLEIC ACIDS RESEARCH

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2)

(2010) D. Schwefel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Vibrio cholerae type VI secretion system displays antimicrobial properties

(2010) D. L. MacIntyre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleases: diversity of structure, function and mechanism

(2010) Wei Yang   QUARTERLY REVIEWS OF BIOPHYSICS

Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI

(2010) Amanda Nga-Sze Mak et al.   STRUCTURE

Cell-free synthesis and characterization of a novel cytotoxic pierisin-like protein from the cabbage butterfly Pieris rapae

(2010) Joachim H.C. Orth et al.   TOXICON

Antimicrobial peptides: The ancient arm of the human immune system

(2010) Jochen Wiesner et al.   Virulence

Discovery of Unique Lanthionine Synthetases Reveals New Mechanistic and Evolutionary Insights

(2010) Yuki Goto et al.   PLOS BIOLOGY

Cholera- and Anthrax-Like Toxins Are among Several New ADP-Ribosyltransferases

(2010) Robert J. Fieldhouse et al.   PLoS Computational Biology

Burkholderia Type VI Secretion Systems Have Distinct Roles in Eukaryotic and Bacterial Cell Interactions

(2010) Sandra Schwarz et al.   PLoS Pathogens

Twenty years hunting for sulfur in DNA

(2010) Shi Chen et al.   Protein & Cell

Lacticin 481 Synthetase as a General Serine/Threonine Kinase

(2009) Young Ok You et al.   ACS Chemical Biology

Horizontal gene transfer between Wolbachia and the mosquito Aedes aegypti

(2009) Lisa Klasson et al.   BMC GENOMICS

Evolutionary diversification of an ancient gene family (rhs) through C-terminal displacement

(2009) Andrew P Jackson et al.   BMC GENOMICS

Myosin VI Undergoes Cargo-Mediated Dimerization

(2009) Cong Yu et al.   CELL

ESX/type VII secretion systems and their role in host–pathogen interaction

(2009) Roxane Simeone et al.   CURRENT OPINION IN MICROBIOLOGY

CD38 as a Regulator of Cellular NAD: A Novel Potential Pharmacological Target for Metabolic Conditions

(2009) Eduardo Chini   CURRENT PHARMACEUTICAL DESIGN

Remodelling of VipA/VipB tubules by ClpV-mediated threading is crucial for type VI protein secretion

(2009) Gabriele Bönemann et al.   EMBO JOURNAL

Endoribonucleases - enzymes gaining spotlight in mRNA metabolism

(2009) Wai Ming Li et al.   FEBS Journal

The Genome of the Amoeba Symbiont "Candidatus Amoebophilus asiaticus" Reveals Common Mechanisms for Host Cell Interaction among Amoeba-Associated Bacteria

(2009) S. Schmitz-Esser et al.   JOURNAL OF BACTERIOLOGY

A Eukaryote-like Cardiolipin Synthase Is Present inStreptomyces coelicolorand in Most Actinobacteria

(2009) Mario Sandoval-Calderón et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological Diversity of Prokaryotic Type IV Secretion Systems

(2009) C. E. Alvarez-Martinez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity

(2009) Fiorella Tonello et al.   MOLECULAR ASPECTS OF MEDICINE

Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen

(2009) C Alejandro Velikovsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Horizontal gene transfer from extinct and extant lineages: biological innovation and the coral of life

(2009) G. P. Fournier et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors

(2009) P. H. Degnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophages Encode Factors Required for Protection in a Symbiotic Mutualism

(2009) K. M. Oliver et al.   SCIENCE

(p)ppGpp: Still Magical?

(2008) Katarzyna Potrykus et al.   Annual Review of Microbiology

Shewanella and Photobacterium spp. in Oysters and Seawater from the Delaware Bay

(2008) G. P. Richards et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Diverse Phage-Encoded Toxins in a Protective Insect Endosymbiont

(2008) P. H. Degnan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Searching protein structure databases with DaliLite v.3

(2008) L. Holm et al.   BIOINFORMATICS

MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases

(2008) Lakshminarayan M Iyer et al.   Biology Direct

Molecular analysis of a novel gene cluster encoding an insect toxin in plant-associated strains ofPseudomonas fluorescens

(2008) Maria Péchy-Tarr et al.   ENVIRONMENTAL MICROBIOLOGY

Cholix Toxin, a Novel ADP-ribosylating Factor fromVibrio cholerae

(2008) René Jørgensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNase A ribonucleases and host defense: an evolving story

(2008) Helene F. Rosenberg   JOURNAL OF LEUKOCYTE BIOLOGY

A novel gene, phcA from Pseudomonas syringae induces programmed cell death in the filamentous fungus Neurospora crassa

(2008) Gale Wichmann et al.   MOLECULAR MICROBIOLOGY

The primary target of the killer toxin fromPichia acaciaeis tRNAGln

(2008) Roland Klassen et al.   MOLECULAR MICROBIOLOGY

Kalign2: high-performance multiple alignment of protein and nucleotide sequences allowing external features

(2008) Timo Lassmann et al.   NUCLEIC ACIDS RESEARCH

The Glycerophosphoryl Diester Phosphodiesterase-Like Proteins SHV3 and its Homologs Play Important Roles in Cell Wall Organization

(2008) Shimpei Hayashi et al.   PLANT AND CELL PHYSIOLOGY

Small Molecule-Induced Allosteric Activation of the Vibrio cholerae RTX Cysteine Protease Domain

(2008) P. J. Lupardus et al.   SCIENCE

AMPylation of Rho GTPases by Vibrio VopS Disrupts Effector Binding and Downstream Signaling

(2008) M. L. Yarbrough et al.   SCIENCE

NAADP: A Universal Ca2+ Trigger

(2008) A. H. Guse et al.   Science Signaling

The AID/APOBEC family of nucleic acid mutators

(2008) Silvestro G Conticello   GENOME BIOLOGY