The PIDDosome, DNA-damage-induced apoptosis and beyond

PIDD4, a novel PIDD isoform without the LRR domain, can independently induce cell apoptosis in cytoplasm

(2011) Lin Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Real time with Caspase-2

(2011) Lisa Bouchier-Hayes et al.   CELL CYCLE

PIDD orchestrates translesion DNA synthesis in response to UV irradiation

(2011) E Logette et al.   CELL DEATH AND DIFFERENTIATION

Proinflammatory Caspase-2-Mediated Macrophage Cell Death Induced by a Rough Attenuated Brucella suis Strain

(2011) Fang Chen et al.   INFECTION AND IMMUNITY

Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop

(2011) Trudy G. Oliver et al.   MOLECULAR CELL

Regulation of PIDD auto-proteolysis and activity by the molecular chaperone Hsp90

(2010) A Tinel et al.   CELL DEATH AND DIFFERENTIATION

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

(2010) T. G. Oliver et al.   GENES & DEVELOPMENT

The Calcium-binding Protein S100B Down-regulates p53 and Apoptosis in Malignant Melanoma

(2010) Jing Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Caspase-9, but Not Caspase-2 or Caspase-8, Is Essential for Heat-induced Apoptosis in Jurkat Cells

(2010) Shary N. Shelton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unpredictable caspase-2: what can it do?

(2010) Helin Vakifahmetoglu-Norberg et al.   TRENDS IN CELL BIOLOGY

DNA damage- and stress-induced apoptosis occurs independently of PIDD

(2009) Ira R. Kim et al.   APOPTOSIS

Caspase-2: controversial killer or checkpoint controller?

(2009) Tanja Kitevska et al.   APOPTOSIS

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2

(2009) Joshua L Andersen et al.   EMBO JOURNAL

Caspase-2 activation in the absence of PIDDosome formation

(2009) Claudia Manzl et al.   JOURNAL OF CELL BIOLOGY

A Cut Above the Other Caspases

(2009) Joshua L. Andersen et al.   MOLECULAR CELL

Characterization of Cytoplasmic Caspase-2 Activation by Induced Proximity

(2009) Lisa Bouchier-Hayes et al.   MOLECULAR CELL

Autoinhibition of UNC5b Revealed by the Cytoplasmic Domain Structure of the Receptor

(2009) Rui Wang et al.   MOLECULAR CELL

Caspase-2 Mediated Apoptotic and Necrotic Murine Macrophage Cell Death Induced by Rough Brucella abortus

(2009) Fang Chen et al.   PLoS One

A tumor suppressor function for caspase-2

(2009) L. H. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3

(2008) Samuel Sidi et al.   CELL

The enigma of caspase-2: the laymen's view

(2008) G Krumschnabel et al.   CELL DEATH AND DIFFERENTIATION

A role for caspase 2 and PIDD in the process of p53-mediated apoptosis

(2008) N. Baptiste-Okoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA