The effect of dichloroacetate on health- and lifespan in C. elegans

Metabolic Networks of Longevity

(2010) Riekelt H. Houtkooper et al.   CELL

Signaling by ROS drives inflammasome activation

(2010) Fabio Martinon   EUROPEAN JOURNAL OF IMMUNOLOGY

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Establishing the Significance and Optimal Intake of Dietary Antioxidants: The Biomarker Concept

(2010) Barry Halliwell   NUTRITION REVIEWS

Caenorhabditis elegans Life Span Studies: The Challenge of Maintaining Synchronous Cohorts

(2010) Jan Gruber et al.   REJUVENATION RESEARCH

Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans

(2009) Kelvin Yen et al.   AGE

The ageing epigenome: Damaged beyond repair?

(2009) David A. Sinclair et al.   AGEING RESEARCH REVIEWS

A novel function of lipid droplets in regulating longevity

(2009) Alexander A. Goldberg et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo

(2009) Ramon C. Sun et al.   BREAST CANCER RESEARCH AND TREATMENT

When a theory of aging ages badly

(2009) Jérôme Lapointe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers

(2009) Daniela Giustarini et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Can we intervene in human ageing?

(2009) Richard G.A. Faragher et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Deceptively simple but simply deceptive -Caenorhabditis eleganslifespan studies: Considerations for aging and antioxidant effects

(2009) Jan Gruber et al.   FEBS LETTERS

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

(2009) A. A. Soukas et al.   GENES & DEVELOPMENT

Quantitative Lipid Analysis and Life Span of thefat-3Mutant of Caenorhabditis elegans

(2009) S. Luke Hillyard et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Number matters: control of mammalian mitochondrial DNA copy number

(2009) Laura L. Clay Montier et al.   Journal of Genetics and Genomics

Can We Develop Genetically Tractable Models to Assess Healthspan (Rather Than Life Span) in Animal Models?

(2009) M. Tatar   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Changing course in ageing research: The Healthy Ageing Phenotype

(2009) Oscar H. Franco et al.   MATURITAS

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans

(2009) Marta Artal-Sanz et al.   NATURE

Mitochondrial function as a determinant of life span

(2009) Ian R. Lanza et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico

(2009) Suresh Kumar Poovathingal et al.   PLoS Computational Biology

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

(2009) Jeremy M. Van Raamsdonk et al.   PLoS Genetics

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

The mitochondrial free radical theory of ageing - Where do we stand?

(2008) Jan Gruber   Frontiers in Bioscience-Landmark

A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted

(2008) Jayan Nagendran et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans

(2008) M. C. Wang et al.   SCIENCE

Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes

(2007) George L. Sutphin et al.   EXPERIMENTAL GERONTOLOGY