Proline dehydrogenase (oxidase) in cancer

Hypoxic Tumor Microenvironments Reduce Collagen I Fiber Density

(2015) Samata M. Kakkad et al.   NEOPLASIA

Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments

(2012) W. Liu et al.   CANCER RESEARCH

Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal

(2012) Kim Zarse et al.   Cell Metabolism

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC

(2012) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Proline Regulatory Axis and Cancer

(2012) James Ming Phang et al.   Frontiers in Oncology

Proline metabolism and cancer

(2011) James et al.   Frontiers in Bioscience-Landmark

PPAR gamma, bioactive lipids, and cancer progression

(2011) Gregory et al.   Frontiers in Bioscience-Landmark

Proline Metabolism and Microenvironmental Stress

(2010) James M. Phang et al.   Annual Review of Nutrition

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

miR-23b* targets proline oxidase, a novel tumor suppressor protein in renal cancer

(2010) W Liu et al.   ONCOGENE

Proline Oxidase Functions as a Mitochondrial Tumor Suppressor in Human Cancers

(2009) Y. Liu et al.   CANCER RESEARCH

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

(2009) A. Hirayama et al.   CANCER RESEARCH

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

(2009) O. Zabirnyk et al.   CARCINOGENESIS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Metabolic profiling reveals key metabolic features of renal cell carcinoma

(2009) Gareth Catchpole et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation and function of proline oxidase under nutrient stress

(2009) Jui Pandhare et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The metabolism of proline, a stress substrate, modulates carcinogenic pathways

(2008) James M. Phang et al.   AMINO ACIDS

PRODH variants and risk for schizophrenia

(2008) Alecia Willis et al.   AMINO ACIDS

Identification of a p53-response element in the promoter of the proline oxidase gene

(2008) Steve A. Maxwell et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers

(2008) Y Liu et al.   ONCOGENE

PPARγand Proline Oxidase in Cancer

(2008) James M. Phang et al.   PPAR Research