Proline Metabolism and Microenvironmental Stress

MYC, microRNAs and glutamine addiction in cancers

(2010) Chi V. Dang   CELL CYCLE

Proline Oxidase Functions as a Mitochondrial Tumor Suppressor in Human Cancers

(2009) Y. Liu et al.   CANCER RESEARCH

Roles of Nox1 and other Nox isoforms in cancer development

(2009) Tohru Kamata   CANCER SCIENCE

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

(2009) O. Zabirnyk et al.   CARCINOGENESIS

Thiazolidinediones in prediabetes and early type 2 diabetes: What can be learned about that disease’s pathogenesis

(2009) Jack L. Leahy   Current Diabetes Reports

Multiple Roles of the Extracellular Matrix in Inflammation

(2009) E. Korpos et al.   CURRENT PHARMACEUTICAL DESIGN

Modulation of intracellular ROS levels by TIGAR controls autophagy

(2009) Karim Bensaad et al.   EMBO JOURNAL

Oxidative stress and hyperuricaemia: pathophysiology, clinical relevance, and therapeutic implications in chronic heart failure

(2009) Corinna Bergamini et al.   EUROPEAN JOURNAL OF HEART FAILURE

Unraveling Δ1-Pyrroline-5-Carboxylate-Proline Cycle in Plants by Uncoupled Expression of Proline Oxidation Enzymes

(2009) Gad Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation and function of proline oxidase under nutrient stress

(2009) Jui Pandhare et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mutations in PYCR1 cause cutis laxa with progeroid features

(2009) Bruno Reversade et al.   NATURE GENETICS

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering

(2009) Elsa C. Chan et al.   PHARMACOLOGY & THERAPEUTICS

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism

(2008) Xin-Hua Liao et al.   AMINO ACIDS

Functional genomics and SNP analysis of human genes encoding proline metabolic enzymes

(2008) Chien-an A. Hu et al.   AMINO ACIDS

Human Δ1-pyrroline-5-carboxylate synthase: function and regulation

(2008) C.-A. A. Hu et al.   AMINO ACIDS

The metabolism of proline, a stress substrate, modulates carcinogenic pathways

(2008) James M. Phang et al.   AMINO ACIDS

PRODH variants and risk for schizophrenia

(2008) Alecia Willis et al.   AMINO ACIDS

Structural biology of proline catabolism

(2008) John J. Tanner   AMINO ACIDS

The importance of proline residues in the structure, stability and susceptibility to proteolytic degradation of collagens

(2008) Stephen M. Krane   AMINO ACIDS

Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations

(2008) A. Lupi et al.   AMINO ACIDS

Targeting the ubiquitin-proteasome system for cancer therapy

(2008) Yili Yang et al.   CANCER SCIENCE

Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L

(2008) I Papandreou et al.   CELL DEATH AND DIFFERENTIATION

Impact of Plasma Oxidized Low-Density Lipoprotein Removal on Atherosclerosis

(2008) Yasushi Ishigaki et al.   CIRCULATION

Hypoxia-inducible factor-1α regulates matrix metalloproteinase-1 activity in human bone marrow-derived mesenchymal stem cells

(2008) Jiunn-Liang Lin et al.   FEBS LETTERS

Covered stents: A review

(2008) Peiman Jamshidi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

A Novel Function for Hydroxyproline Oxidase in Apoptosis through Generation of Reactive Oxygen Species

(2008) Sandra K. Cooper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers

(2008) Y Liu et al.   ONCOGENE

Basic Science Review: Nitric Oxide—Releasing Prosthetic Materials

(2008) Vinit N. Varu et al.   Vascular and Endovascular Surgery

PPARγand Proline Oxidase in Cancer

(2008) James M. Phang et al.   PPAR Research

Synergistic Effects of PPARγLigands and Retinoids in Cancer Treatment

(2008) Masahito Shimizu et al.   PPAR Research