Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1

A Cyclic Peptidic Serine Protease Inhibitor: Increasing Affinity by Increasing Peptide Flexibility

(2014) Baoyu Zhao et al.   PLoS One

Serpin latency transition at atomic resolution

(2014) G. Cazzolli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thrombosis: A major contributor to global disease burden

(2014) G.E. Raskob et al.   THROMBOSIS RESEARCH

Structural Insight into Inactivation of Plasminogen Activator Inhibitor-1 by a Small-Molecule Antagonist

(2013) Zhonghui Lin et al.   CHEMISTRY & BIOLOGY

Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism

(2012) W. Li et al.   BLOOD

Crystal structure of the native plasminogen reveals an activation-resistant compact conformation

(2012) Y. XUE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

(2012) N. Korin et al.   SCIENCE

The Biochemistry, Physiology and Pathological roles of PAI-1 and the requirements for PAI-1 inhibition in vivo

(2012) Britt Van De Craen et al.   THROMBOSIS RESEARCH

Role of Tissue Plasminogen Activator in Acute Ischemic Stroke

(2011) Molly A Hatcher et al.   ANNALS OF PHARMACOTHERAPY

Structural Basis for Recognition of Urokinase-type Plasminogen Activator by Plasminogen Activator Inhibitor-1

(2011) Zhonghui Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

REVIEW: Plasminogen Activator Inhibitor-1 (PAI-1): A Key Factor Linking Fibrinolysis and Age-Related Subclinical and Clinical Conditions

(2010) Matteo Cesari et al.   Cardiovascular Therapeutics

Role of residue Y99 in tissue plasminogen activator

(2010) Alessandro Vindigni et al.   PROTEIN SCIENCE

Biochemical properties of plasminogen activator inhibitor-1

(2009) Daniel Miotto Dupont   Frontiers in Bioscience-Landmark

Molecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complex

(2009) D. J. D. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA