Breaking on through to the other side: protein export through the bacterial Sec system

Structure of the SecY Complex Unlocked by a Preprotein Mimic

(2012) Dilem Hizlan et al.   Cell Reports

β-Barrel Membrane Protein Assembly by the Bam Complex

(2011) Christine L. Hagan et al.   Annual Review of Biochemistry

Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo

(2011) Eugene Oh et al.   CELL

SecA, a remarkable nanomachine

(2011) Ilja Kusters et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A single copy of SecYEG is sufficient for preprotein translocation

(2011) Alexej Kedrov et al.   EMBO JOURNAL

Energetics of SecA Dimerization

(2011) Andy J. Wowor et al.   JOURNAL OF MOLECULAR BIOLOGY

SecA Interacts with Ribosomes in Order to Facilitate Posttranslational Translocation in Bacteria

(2011) Damon Huber et al.   MOLECULAR CELL

Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

(2011) Jens Frauenfeld et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Signal peptidase I: Cleaving the way to mature proteins

(2011) Sarah M. Auclair et al.   PROTEIN SCIENCE

The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor

(2011) S. F. Ataide et al.   SCIENCE

Quaternary Structure of SecA in Solution and Bound to SecYEG Probed at the Single Molecule Level

(2011) Ilja Kusters et al.   STRUCTURE

Lipoprotein Sorting in Bacteria

(2010) Suguru Okuda et al.   Annual Review of Microbiology

Transport and proofreading of proteins by the twin-arginine translocation (Tat) system in bacteria

(2010) Colin Robinson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure and function of the molecular chaperone Trigger Factor

(2010) Anja Hoffmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Oligomeric State and Arrangement of the Active Bacterial Translocon

(2010) Karine Deville et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SecA: a tale of two protomers

(2010) Marios Frantzeskos Sardis et al.   MOLECULAR MICROBIOLOGY

Recognition of a signal peptide by the signal recognition particle

(2010) Claudia Y. Janda et al.   NATURE

Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes

(2010) P. F. Egea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of the binding frame within a physiological ligand for the chaperone SecB

(2010) Traci B. Topping et al.   PROTEIN SCIENCE

Sequential Checkpoints Govern Substrate Selection During Cotranslational Protein Targeting

(2010) X. Zhang et al.   SCIENCE

Dynamics of SecY Translocons with Translocation-Defective Mutations

(2010) Ana-Nicoleta Bondar et al.   STRUCTURE

Proteolytic processing of Escherichia coli twin-arginine signal peptides by LepB

(2009) Iris Lüke et al.   ARCHIVES OF MICROBIOLOGY

Promiscuous Substrate Recognition in Folding and Assembly Activities of the Trigger Factor Chaperone

(2009) Erik Martinez-Hackert et al.   CELL

Conformational Flexibility and Peptide Interaction of the Translocation ATPase SecA

(2009) Jochen Zimmer et al.   JOURNAL OF MOLECULAR BIOLOGY

SecB—A chaperone dedicated to protein translocation

(2009) Philipp Bechtluft et al.   Molecular BioSystems

Signal peptides are allosteric activators of the protein translocase

(2009) Giorgos Gouridis et al.   NATURE

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

(2009) Günter Kramer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Universal Protein Resource (UniProt) in 2010

(2009)   NUCLEIC ACIDS RESEARCH

Signal Sequences Activate the Catalytic Switch of SRP RNA

(2009) N. Bradshaw et al.   SCIENCE

EchoLOCATION: an in silico analysis of the subcellular locations of Escherichia coli proteins and comparison with experimentally derived locations

(2008) Richard S. P. Horler et al.   BIOINFORMATICS

Molecular mechanism and structure of Trigger Factor bound to the translating ribosome

(2008) Frieder Merz et al.   EMBO JOURNAL

Synthetic peptides identify a second periplasmic site for the plug of the SecYEG protein translocation complex

(2008) Alice Robson et al.   FEBS LETTERS

Full-lengthEscherichia coliSecA Dimerizes in a Closed Conformation in Solution as Determined by Cryo-electron Microscopy

(2008) Yong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clamour for a kiss

(2008) Anastassios Economou   NATURE

Structure of a complex of the ATPase SecA and the protein-translocation channel

(2008) Jochen Zimmer et al.   NATURE

Conformational transition of Sec machinery inferred from bacterial SecYE structures

(2008) Tomoya Tsukazaki et al.   NATURE

SRP RNA controls a conformational switch regulating the SRP–SRP receptor interaction

(2008) Saskia B Neher et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Signal sequence–independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel

(2008) Thomas Bornemann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single Copies of Sec61 and TRAP Associate with a Nontranslating Mammalian Ribosome

(2008) Jean-François Ménétret et al.   STRUCTURE