Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle

(2013) Yang Liu et al.   CELLULAR SIGNALLING

Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle

(2012) Serge Ducommun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle

(2012) Yu-Chiang Lai et al.   BIOCHEMICAL JOURNAL

Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1

(2012) Dave Bridges et al.   MOLECULAR BIOLOGY OF THE CELL

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P

(2012) S. N. Zolov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of PIKfyve phosphorylation by insulin and osmotic stress

(2010) Elaine V. Hill et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3)

(2010) Véronique Mouton et al.   BIOCHEMICAL JOURNAL

TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle

(2010) D. An et al.   DIABETES

Requirement for distinct vesicle-associated membrane proteins in insulin- and AMP-activated protein kinase (AMPK)-induced translocation of GLUT4 and CD36 in cultured cardiomyocytes

(2010) R. W. Schwenk et al.   DIABETOLOGIA

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase

(2010) Louise Lantier et al.   FASEB JOURNAL

Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents

(2010) Yu-Chiang Lai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Phosphatidylinositol 3,5-Bisphosphate (PI(3,5)P2) Potentiates Cardiac Contractility via Activation of the Ryanodine Receptor

(2010) Chad D. Touchberry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated protein kinase in contraction regulation of skeletal muscle metabolism: necessary and/or sufficient?

(2009) T. E. Jensen et al.   Acta Physiologica

YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes

(2009) Ognian C. Ikonomov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK and the biochemistry of exercise: implications for human health and disease

(2009) Erik A. Richter et al.   BIOCHEMICAL JOURNAL

Inhibition of Contraction-Stimulated AMP-Activated Protein Kinase Inhibits Contraction-Stimulated Increases in PAS-TBC1D1 and Glucose Transport Without Altering PAS-AS160 in Rat Skeletal Muscle

(2009) K. Funai et al.   DIABETES

Sac3 Is an Insulin-regulated Phosphatidylinositol 3,5-Bisphosphate Phosphatase

(2009) Ognian C. Ikonomov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal Muscle AMP-activated Protein Kinase Is Essential for the Metabolic Response to Exercisein Vivo

(2009) Robert S. Lee-Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The molecular basis of insulin-stimulated glucose uptake: signalling, trafficking and potential drug targets

(2009) Sophie E Leney et al.   JOURNAL OF ENDOCRINOLOGY

Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca2+ homeostasis

(2009) Jinhua Shen et al.   NATURE CELL BIOLOGY

PIKfyve Regulation of Endosome-Linked Pathways

(2009) Jane de Lartigue et al.   TRAFFIC

The α-subunit of AMPK is essential for submaximal contraction-mediated glucose transport in skeletal muscle in vitro

(2008) Natalie Lefort et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

(2008) Kei Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PIKfyve: Partners, significance, debates and paradoxes

(2008) A SHISHEVA   CELL BIOLOGY INTERNATIONAL

A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding

(2008) Harold B J Jefferies et al.   EMBO REPORTS

AMP-activated Protein Kinase Phosphorylates and Desensitizes Smooth Muscle Myosin Light Chain Kinase

(2008) Sandrine Horman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY