A2Aadenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase

Allosteric modulation of adenosine receptors

(2010) Anikó Göblyös et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Adenosine Receptors: What We Know and What We are Learning

(2010) M.L. Trincavelli et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structure-Based Discovery of Novel Chemotypes for Adenosine A2AReceptor Antagonists

(2010) Vsevolod Katritch et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure-Based Discovery of A2AAdenosine Receptor Ligands

(2010) Jens Carlsson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist–antagonist binding modulation

(2009) Vicent Casadó et al.   BIOCHEMICAL PHARMACOLOGY

Immunological dysfunction in HIV-1-infected individuals caused by impairment of adenosine deaminase-induced costimulation of T-cell activation

(2009) José M. Martinez-Navio et al.   IMMUNOLOGY

Adenosine deaminase enhances T-cell response elicited by dendritic cells loaded with inactivated HIV

(2009) Núria Climent et al.   IMMUNOLOGY AND CELL BIOLOGY

Building a new conceptual framework for receptor heteromers

(2009) Sergi Ferré et al.   Nature Chemical Biology

GPCR homomers and heteromers: A better choice as targets for drug development than GPCR monomers?

(2009) Vicent Casadó et al.   PHARMACOLOGY & THERAPEUTICS

A2A Adenosine Receptor and its Modulators: Overview on a Druggable GPCR and on Structure-Activity Relationship Analysis and Binding Requirements of Agonists and Antagonists

(2008) G. Cristalli et al.   CURRENT PHARMACEUTICAL DESIGN

Potential Therapeutic Interest of Adenosine A2A Receptors in Psychiatric Disorders

(2008) Rodrigo Cunha et al.   CURRENT PHARMACEUTICAL DESIGN

Detection of higher-order G protein-coupled receptor oligomers by a combined BRET-BiFC technique

(2008) Jorge Gandia et al.   FEBS LETTERS

Reduced ligand affinity leads to an impaired function of the adenosine A2Areceptor of human granulocytes in sepsis

(2008) Simone Kreth et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human adenosine deaminase as an allosteric modulator of human A1adenosine receptor: abolishment of negative cooperativity for [3H](R)-pia binding to the caudate nucleus

(2008) Eduard Gracia et al.   JOURNAL OF NEUROCHEMISTRY

Detection of heteromerization of more than two proteins by sequential BRET-FRET

(2008) Paulina Carriba et al.   NATURE METHODS

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

(2008) P. Jeffrey Conn et al.   NATURE REVIEWS DRUG DISCOVERY