Cysteine Cathepsins Activate ELR Chemokines and Inactivate Non-ELR Chemokines

Cysteine cathepsins and extracellular matrix degradation

(2014) Marko Fonović et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Macrophage Matrix Metalloproteinase-12 Dampens Inflammation and Neutrophil Influx in Arthritis

(2014) Caroline L. Bellac et al.   Cell Reports

Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web

(2014) Nikolaus Fortelny et al.   PLOS BIOLOGY

Role of ADAM-17, p38 MAPK, Cathepsins, and the Proteasome Pathway in the Synthesis and Shedding of Fractalkine/CX3CL1 in Rheumatoid Arthritis

(2013) Brian A. Jones et al.   ARTHRITIS AND RHEUMATISM

The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes

(2012) Dejan Caglič et al.   BIOLOGICAL CHEMISTRY

Protease signalling: the cutting edge

(2012) Boris Turk et al.   EMBO JOURNAL

Biochemical Characterization and N-terminomics Analysis of Leukolysin, the Membrane-type 6 Matrix Metalloprotease (MMP25)

(2012) Amanda E. Starr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model

(2011) Anna K. Clark et al.   ARTHRITIS AND RHEUMATISM

Cysteine cathepsins: From structure, function and regulation to new frontiers

(2011) Vito Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Chemokine oligomerization and interactions with receptors and glycosaminoglycans: The role of structural dynamics in function

(2011) C.L. Salanga et al.   EXPERIMENTAL CELL RESEARCH

Biochemical Analysis of Matrix Metalloproteinase Activation of Chemokines CCL15 and CCL23 and Increased Glycosaminoglycan Binding of CCL16

(2011) Amanda E. Starr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic Identification of Protease Cleavage Sites Characterizes Prime and Non-prime Specificity of Cysteine Cathepsins B, L, and S

(2011) Martin L. Biniossek et al.   JOURNAL OF PROTEOME RESEARCH

Processing of CXCL12 by Different Osteoblast-Secreted Cathepsins

(2011) Nicole D. Staudt et al.   STEM CELLS AND DEVELOPMENT

Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation

(2010) Dejan Caglič et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Interleukin-6 Increases Expression and Secretion of Cathepsin B by Breast Tumor-Associated Monocytes

(2010) Mona Mohamed et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effect of posttranslational processing on the in vitro and in vivo activity of chemokines

(2010) Anneleen Mortier et al.   EXPERIMENTAL CELL RESEARCH

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

(2010) V. Gocheva et al.   GENES & DEVELOPMENT

Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?

(2009) Boris Turk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Liberation of Fractalkine in the Dorsal Horn Requires Microglial Cathepsin S

(2009) A. K. Clark et al.   JOURNAL OF NEUROSCIENCE

Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx

(2008) R. A. Dean et al.   BLOOD

Stromal cell-derived factors 1α and 1β, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8

(2008) Katerina Ajami et al.   FEBS LETTERS

Matrix Metalloproteinase Processing of CXCL11/I-TAC Results in Loss of Chemoattractant Activity and Altered Glycosaminoglycan Binding

(2008) Jennifer H. Cox et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitory Fragment from the p41 Form of Invariant Chain Can Regulate Activity of Cysteine Cathepsins in Antigen Presentation

(2008) Marko Mihelič et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of chemokine activity by posttranslational modification

(2008) A MORTIER et al.   PHARMACOLOGY & THERAPEUTICS

Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion

(2007) Olga Vasiljeva et al.   BIOCHIMIE