Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web

A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity

(2014) David J Marchant et al.   NATURE MEDICINE

Protein TAILS: when termini tell tales of proteolysis and function

(2013) Philipp F Lange et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Fetuin-B, a Liver-Derived Plasma Protein Is Essential for Fertilization

(2013) Eileen Dietzel et al.   DEVELOPMENTAL CELL

Systems-Level Analysis of Proteolytic Events in Increased Vascular Permeability and Complement Activation in Skin Inflammation

(2013) U. auf dem Keller et al.   Science Signaling

Missing the target: matrix metalloproteinase antitargets in inflammation and cancer

(2013) Antoine Dufour et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Crystal Structure of Human α2-Macroglobulin Reveals a Unique Molecular Cage

(2012) Aniebrys Marrero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NSP4, an elastase-related protease in human neutrophils with arginine specificity

(2012) N. C. Perera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cysteine Protease Inhibitors: from Evolutionary Relationships to Modern Chemotherapeutic Design for the Treatment of Infectious Diseases

(2011) E. C.Y. Toh et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

TopFIND, a knowledgebase linking protein termini with function

(2011) Philipp F Lange et al.   NATURE METHODS

neXtProt: a knowledge platform for human proteins

(2011) L. Lane et al.   NUCLEIC ACIDS RESEARCH

TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function

(2011) P. F. Lange et al.   NUCLEIC ACIDS RESEARCH

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2011) N. D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Proteolytic networks in cancer

(2011) Steven D. Mason et al.   TRENDS IN CELL BIOLOGY

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Interdependence of kallikrein-related peptidases in proteolytic networks

(2010) Nathalie Beaufort et al.   BIOLOGICAL CHEMISTRY

Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response

(2010) Kai Kessenbrock et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Multiplex N-terminome Analysis of MMP-2 and MMP-9 Substrate Degradomes by iTRAQ-TAILS Quantitative Proteomics

(2010) Anna Prudova et al.   MOLECULAR & CELLULAR PROTEOMICS

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

(2010) Oded Kleifeld et al.   NATURE BIOTECHNOLOGY

Complementary positional proteomics for screening substrates of endo- and exoproteases

(2010) Petra Van Damme et al.   NATURE METHODS

Proteome-wide analysis of protein carboxy termini: C terminomics

(2010) Oliver Schilling et al.   NATURE METHODS

Emerging principles in protease-based drug discovery

(2010) Marcin Drag et al.   NATURE REVIEWS DRUG DISCOVERY

Updated Biological Roles for Matrix Metalloproteinases and New “Intracellular” Substrates Revealed by Degradomics

(2009) Georgina S. Butler et al.   BIOCHEMISTRY

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

(2009) Georgina S. Butler et al.   NATURE REVIEWS DRUG DISCOVERY

KEGG for representation and analysis of molecular networks involving diseases and drugs

(2009) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

InParanoid 7: new algorithms and tools for eukaryotic orthology analysis

(2009) G. Ostlund et al.   NUCLEIC ACIDS RESEARCH

Functional genetic mouse models: promising tools for investigation of the proteolytic internet

(2008) Achim Krüger   BIOLOGICAL CHEMISTRY

Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

(2008) Sami Mahrus et al.   CELL

Matrix Metalloproteinase Processing of CXCL11/I-TAC Results in Loss of Chemoattractant Activity and Altered Glycosaminoglycan Binding

(2008) Jennifer H. Cox et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteases: Multifunctional Enzymes in Life and Disease

(2008) Carlos López-Otín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metadegradomics

(2008) Alain Doucet et al.   MOLECULAR & CELLULAR PROTEOMICS