Lipid Requirements for the Enzymatic Activity of MraY Translocases andin VitroReconstitution of the Lipid II Synthesis Pathway

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

A subset of annular lipids is linked to the flippase activity of an ABC transporter

(2015) Chérine Bechara et al.   Nature Chemistry

Structural characterization of muropeptides fromChlamydia trachomatispeptidoglycan by mass spectrometry resolves “chlamydial anomaly”

(2015) Mathanraj Packiam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzymatic Synthesis of Lipid II and Analogues

(2014) Lin-Ya Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reconstitution of the peptidoglycan cytoplasmic precursor biosynthetic pathway in cell-free system and rapid screening of antisense oligonucleotides for Mur enzymes

(2014) Jiayuan Sheng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification of novel inhibitors of phospho-MurNAc-pentapeptide translocase MraY from library screening: Isoquinoline alkaloid michellamine B and xanthene dye phloxine B

(2014) Agnes Mihalyi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hydrophobic supplements in cell-free systems: Designing artificial environments for membrane proteins

(2014) Christopher Hein et al.   ENGINEERING IN LIFE SCIENCES

Structural evidence for functional lipid interactions in the betaine transporter BetP

(2013) Caroline Koshy et al.   EMBO JOURNAL

A new metabolic cell-wall labelling method reveals peptidoglycan in Chlamydia trachomatis

(2013) G. W. Liechti et al.   NATURE

Crystal Structure of MraY, an Essential Membrane Enzyme for Bacterial Cell Wall Synthesis

(2013) B. C. Chung et al.   SCIENCE

Characterization of co-translationally formed nanodisc complexes with small multidrug transporters, proteorhodopsin and with the E. coli MraY translocase

(2012) Christian Roos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipodepsipeptide Empedopeptin Inhibits Cell Wall Biosynthesis through Ca2+-dependent Complex Formation with Peptidoglycan Precursors

(2012) Anna Müller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Action and Limited Cross-Resistance of New Lipopeptide MX-2401

(2011) E. Rubinchik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Feglymycin is an Inhibitor of the Enzymes MurA and MurC of the Peptidoglycan Biosynthesis Pathway

(2011) Saskia Rausch et al.   CHEMBIOCHEM

The Large Extracellular Loop of Organic Cation Transporter 1 Influences Substrate Affinity and Is Pivotal for Oligomerization

(2011) Thorsten Keller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preparative Scale Cell-free Production and Quality Optimization of MraY Homologues in Different Expression Modes

(2011) Yi Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-Free Expression and Assembly of ATP Synthase

(2011) Doreen Matthies et al.   JOURNAL OF MOLECULAR BIOLOGY

Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation

(2011) Miriam Wilmes et al.   NATURAL PRODUCT REPORTS

Modulation of G-protein coupled receptor sample quality by modified cell-free expression protocols: A case study of the human endothelin A receptor

(2010) Friederike Junge et al.   JOURNAL OF STRUCTURAL BIOLOGY

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

The Lipopeptide Antibiotic Friulimicin B Inhibits Cell Wall Biosynthesis through Complex Formation with Bactoprenol Phosphate

(2009) T. Schneider et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Functional conservation of the lipid II biosynthesis pathway in the cell wall-less bacteriaChlamydiaandWolbachia: why is lipid II needed?

(2009) Beate Henrichfreise et al.   MOLECULAR MICROBIOLOGY

Lipids and membrane protein structures

(2008) C HUNTE et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY