Macrophage-specificde NovoSynthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity
出版年份 2015 全文链接
标题
Macrophage-specificde NovoSynthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 49, Pages 29402-29413
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2015-10-06
DOI
10.1074/jbc.m115.680199
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis
- (2015) Jonathan Y. Xia et al. Cell Metabolism
- Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance
- (2014) Jing Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance
- (2014) Sarah M. Turpin et al. Cell Metabolism
- Macrophages, Immunity, and Metabolic Disease
- (2014) Joanne C. McNelis et al. IMMUNITY
- Inflammasomes and Metabolic Disease
- (2013) Jorge Henao-Mejia et al. Annual Review of Physiology
- The adipokine/ceramide axis: Key aspects of insulin sensitization
- (2013) Jonathan Y. Xia et al. BIOCHIMIE
- Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation
- (2013) Xiaoyuan Xu et al. Cell Metabolism
- B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance
- (2013) Daniel A. Winer et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments
- (2013) Moritz Haneklaus et al. CURRENT OPINION IN IMMUNOLOGY
- Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation
- (2013) Yiqing Yan et al. IMMUNITY
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Myeloid cell–specific serine palmitoyltransferase subunit 2 haploinsufficiency reduces murine atherosclerosis
- (2013) Mahua Chakraborty et al. JOURNAL OF CLINICAL INVESTIGATION
- Ceramide kinase deficiency improves diet-induced obesity and insulin resistance
- (2012) Susumu Mitsutake et al. FEBS LETTERS
- Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages
- (2012) Joel D. Schilling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammatory Mechanisms in Obesity
- (2011) Margaret F. Gregor et al. Annual Review of Immunology
- Hematopoietic Cell-Restricted Deletion of CD36 Reduces High-Fat Diet-Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue
- (2011) H. T. Nicholls et al. DIABETES
- Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice
- (2011) Michael J. Jurczak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ceramide metabolism is affected by obesity and diabetes in human adipose tissue
- (2011) A.U. Błachnio-Zabielska et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Ceramides as modulators of cellular and whole-body metabolism
- (2011) Benjamin T. Bikman et al. JOURNAL OF CLINICAL INVESTIGATION
- Inflammatory links between obesity and metabolic disease
- (2011) Carey N. Lumeng et al. JOURNAL OF CLINICAL INVESTIGATION
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
- (2011) Daniel A Winer et al. NATURE MEDICINE
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Inflammasome is a central player in the induction of obesity and insulin resistance
- (2011) R. Stienstra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance
- (2010) Hui-Young Lee et al. Cell Metabolism
- Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
- (2010) J. R. Ussher et al. DIABETES
- Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice
- (2010) J. E. Ayala et al. Disease Models & Mechanisms
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome
- (2009) Guang Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Liver-specific Deficiency of Serine Palmitoyltransferase Subunit 2 Decreases Plasma Sphingomyelin and Increases Apolipoprotein E Levels
- (2009) Zhiqiang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
- (2009) Satoshi Nishimura et al. NATURE MEDICINE
- Normalization of obesity-associated insulin resistance through immunotherapy
- (2009) Shawn Winer et al. NATURE MEDICINE
- Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
- (2008) C. N. Lumeng et al. DIABETES
- Protection from High Fat Diet-induced Increase in Ceramide in Mice Lacking Plasminogen Activator Inhibitor 1
- (2008) Charmi Shah et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells
- (2007) Joan Villena et al. FREE RADICAL BIOLOGY AND MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation