Article
Engineering, Environmental
Reshma T. Mohan, M. S. Mohan Kumar, Lakshminarayana Rao
Summary: This study developed a multiphase mixture CFD model with the PBM add-on and species transport model to predict oxygen mass transfer in a diffused aeration system. Results showed that by decreasing air bubble size, the oxygen mass transfer coefficient increased by 15% and improved distribution of air bubbles, leading to enhanced oxygen transfer efficiency.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Thermodynamics
Qingye Li, Chaoyong Zong, Fuwen Liu, Tianhang Xue, Ao Zhang, Xueguan Song
Summary: In this study, a modified cavitation model combining local flow characteristics, supervised learning, and genetic algorithms is proposed to investigate the cavitation flow characteristics of orifice plates under high-pressure conditions. The modified cavitation model eliminates the influence of the bubble diameter and nucleation site volume fraction on mass flow rate and achieves dimensionality reduction at the physical level. The relationship between evaporation/condensation coefficients and mass flow rate is constructed by supervised learning, and the two coefficients are determined using the genetic algorithm. The accuracy of the modified cavitation model is proved by calculating the mass flow rates within a 5% experiment error.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2023)
Article
Thermodynamics
Sameed Akber, Christopher T. DeGroot, Kamran Siddiqui
Summary: This research aims to thermally regulate photobioreactors using phase change materials, in order to minimize temperature variations and improve microalgae yield. The study investigates the flow and thermal behaviors in a channel with thermal energy storage columns using numerical simulations. A parametric analysis shows that geometric parameters influence the thermal energy storage in PCM-filled columns.
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
(2023)
Article
Environmental Sciences
Linlin Huang, Da Li, Junfeng Liu, Lisha Yang, Changchao Dai, Nanqi Ren, Yujie Feng
Summary: The study revealed the significant impact of cathode configuration on electro-catalytic activities, showing that a mesh Ti cathode can improve phenol degradation rates by optimizing fluid flow for pollutant transfer. Excellent agreement was found between computational fluid dynamics simulation and experimental analysis, with the mass transfer coefficient of mesh Ti significantly higher than that of planar cathode.
Article
Engineering, Chemical
Hariswaran Sitaraman, Ilenia Battiato
Summary: We present well-resolved computational fluid dynamics simulations of a large-scale reverse osmosis membrane-spacer configuration. The study reveals different concentration profile development characteristics at different flow rates and proposes a modified mass-transfer correlation that considers the development of the concentration boundary layer. Additionally, the study finds that a non-uniform arrangement of spacers can significantly reduce pressure drop.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Engineering, Chemical
George M. Teke, Godfrey K. Gakingo, Robert W. M. Pott
Summary: This study reports on the numerical investigation of a semi-partition bioreactor (SPB) designed for in-situ extractive fermentation. The findings suggest that the SPB can effectively facilitate liquid-liquid partitioning and mass transfer, making it a potential route for fermentations susceptible to product inhibition.
CHEMICAL ENGINEERING SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Long Chen, Binxin Wu
Summary: Membrane distillation (MD) is a promising water treatment technology with various applications, but further research is needed to determine appropriate industrial implementation. Computational fluid dynamics (CFD) has been widely used in analyzing MD processes and developing novel membranes, but there is still a need for more comprehensive and in-depth research in the field.
Article
Engineering, Chemical
Thomas P. John, Claudio P. Fonte, Adam Kowalski, Thomas L. Rodgers
Summary: In this study, an angular momentum balance combined with computational fluid dynamics was used to correlate the power, flow, and mixer geometry of down-pumping pitched blade turbine geometries. The models developed from the results allow the prediction of power from flow (or vice versa) for different geometries, and it was found that the choice of measurement method can affect the relationship between power, flow, and impeller geometry.
Article
Engineering, Chemical
Mehrad Ansari, Heta A. Gandhi, David G. Foster, Andrew D. White
Summary: Computational fluid dynamics (CFD) analysis is widely used in chemical engineering. In this study, active learning (AL) and symbolic regression (SR) are combined to obtain symbolic equations for system variables from CFD simulations. This scalable approach is applicable for any desired number of CFD design parameters.
Article
Engineering, Chemical
Kirill Mikhaylov, Stelios Rigopoulos, George Papadakis
Summary: The study combines reduced order modeling and system identification to reconstruct the temporal evolution of large-scale vortical structures behind the blades of a Rushton impeller. The results demonstrate that even using the velocity time signal from a single sensor point, the first pair of modes can be reconstructed well. Increasing the number of sensor points improves accuracy and stability, leading to better reconstruction of the second pair of POD modes. The estimator derived at Reynolds number 600 shows robustness when applied to flows at Reynolds numbers 500 and 700.
Article
Engineering, Mechanical
F. Mabood, T. A. Yusuf, S. A. Shehzad, I. A. Badruddin
Summary: This research investigates the features of triple diffusion in naturally convected viscous material flow through a horizontal plate embedded in a porous regime. The heat and mass transmission process is evaluated using the Cattaneo and Christov (CC) models, and entropy analysis is conducted based on the second law of thermodynamics. The results show an increase in entropy generation rate at the convective wall.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART C-JOURNAL OF MECHANICAL ENGINEERING SCIENCE
(2022)
Article
Thermodynamics
Diego Alcaniz, Paolo Caccavale, Maria Valeria De Bonis, Ruth de los Reyes, Maria Dolores Ortola, Gianpaolo Ruocco
Summary: A new fluid heater based on BCET was proposed in this paper, with fully-dimensional thermo-fluid analysis implemented to achieve more uniform and effective heat transfer to temperature-sensitive working fluids. Through geometry optimization with internal baffles, the uncontrolled temperature excess was significantly reduced, while the pressure drop across the flow device was also lowered.
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
(2021)
Article
Engineering, Chemical
Liang Li, Runqiu Hao, Xiaoxia Jin, Yachao Hao, Chunming Fu, Chengkai Zhang, Xihui Gu
Summary: A three-dimensional CFD transient model is developed to predict the species concentration distribution in the biodegradation of phenol in an airlift reactor. The model uses the Euler-Euler method coupled with the standard k-epsilon model to determine the gas-liquid flow and predicts the bubble size using the population balance model. A turbulent mass diffusivity model is proposed to simulate the turbulent mass transfer process and predict the species concentration distribution. The model shows good agreement with experimental results and suggests that assuming a constant turbulent Schmidt number is not reasonable.
Article
Engineering, Chemical
Maulana G. Nugraha, Ronnie Andersson, Bengt Andersson
Summary: This study introduces new models for mass transfer to spheres under three different conditions: mass transfer without Stefan flow, mass transfer with even Stefan flow, and mass transfer with uneven flux driven Stefan flow. The new models, derived from high resolved computational fluid dynamic simulations, show improved accuracy and reduced relative error, especially for higher Sc numbers.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Engineering, Chemical
Thomas P. John, Claudio P. Fonte, Adam Kowalski, Thomas L. Rodgers
Summary: This study comprehensively investigates the effect of impeller geometry on the relationship between power and flow in stirred vessels using a combination of angular momentum balance analysis and computational fluid dynamics simulations. The results allow for accurate prediction of the flow generated by the impeller based on easily measurable impeller power consumption and geometrical dimensions. The models are accurate over a wide range of geometries and can predict both primary and total flows.
Article
Pharmacology & Pharmacy
Lei Luo, Yiming Qi, Hong Zhong, Shinan Jiang, Hu Zhang, Hao Cai, Yahui Wu, Zhongwei Gu, Qiyong Gong, Kui Luo
Summary: In this study, a redox-responsive polymeric prodrug was synthesized by RAFT polymerization for precise delivery of combinational therapeutic agents. The prodrug exhibited a chemo-photodynamic therapeutic effect to kill breast cancer cells and showed a remarkable in vivo anticancer efficacy. The findings suggest that the redox-responsive polymeric prodrug has great potential as an anti-cancer agent for combinational therapy.
ACTA PHARMACEUTICA SINICA B
(2022)
Article
Engineering, Biomedical
Junnan Tang, Xiaolin Cui, Zenglei Zhang, Yanyan Xu, Jiacheng Guo, Bram G. Soliman, Yongzheng Lu, Zhen Qin, Qiguang Wang, Hu Zhang, Khoon S. Lim, Tim B. F. Woodfield, Jinying Zhang
Summary: This study proposes a non-injection method for delivering EVs onto the heart surface to treat MI by spraying a mixture of EVs, GelMA precursors, and photoinitiators. The physically entrapped EVs within the GelMA hydrogel network have an enhanced retention rate and are gradually released through diffusion and/or enzymatic degradation to exert a therapeutic effect in the heart tissue.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Qiang Luo, Zhenyu Duan, Xiaoling Li, Lei Gu, Long Ren, Hongyan Zhu, Xiaohe Tian, Rongjun Chen, Hu Zhang, Qiyong Gong, Zhongwei Gu, Kui Luo
Summary: Combining photodynamic therapy with AZD2281, a TME-activatable photodynamic nanoagent was designed to induce immune responses in tumors, showing potential for anti-cancer treatment.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Dayi Pan, Xiuli Zheng, Lu Zhang, Xin Li, Guonian Zhu, Meng Gong, Michal Kopytynski, Luonan Zhou, Yong Yi, Hongyan Zhu, Xiaohe Tian, Rongjun Chen, Hu Zhang, Zhongwei Gu, Qiyong Gong, Kui Luo
Summary: In this study, a combination nanotherapeutic was developed by constructing co-assembled nanoparticles using two amphiphilic conjugates. In vitro and in vivo studies confirmed the synergistic effect of this nanotherapeutic in treating tumors, and metabolic variations revealed the association between tumor suppression and disruption of metabolic homeostasis.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Hao Cai, Ping Tan, Xiaoting Chen, Michal Kopytynski, Dayi Pan, Xiuli Zheng, Lei Gu, Qiyong Gong, Xiaohe Tian, Zhongwei Gu, Hu Zhang, Rongjun Chen, Kui Luo
Summary: This study presents a smart drug-delivery system, LD-DOX/Ce6, based on LDBCs. LD-DOX/Ce6 can specifically release DOX and Ce6 in the tumor microenvironment, resulting in a synergistic chemo-photodynamic antitumor efficacy.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Lei Gu, Zhenyu Duan, Xiaoting Chen, Xiaoling Li, Qiang Luo, Apanpreet Bhamra, Dayi Pan, Hongyan Zhu, Xiaohe Tian, Rongjun Chen, Zhongwei Gu, Hu Zhang, Zhiyong Qian, Qiyong Gong, Kui Luo
Summary: Efficient penetration and retention of therapeutic agents in tumor tissues can be achieved through rational design of drug delivery systems. In this study, a polymer-dendron conjugate is proposed, which undergoes a structural transformation triggered by a specific enzyme, leading to the release of therapeutic agents and interaction with tumor cell membranes for deep penetration and prolonged retention in the tumor tissues. Additionally, this conjugate disrupts cell homeostasis, making tumor cells more susceptible to photodynamic therapy.
ADVANCED MATERIALS
(2022)
Article
Engineering, Biomedical
Qiang Luo, Ling Lin, Qiaorong Huang, Zhenyu Duan, Lei Gu, Hu Zhang, Zhongwei Gu, Qiyong Gong, Kui Luo
Summary: In this study, an enzyme- and pH-responsive polymeric prodrug was developed by combining a dendronized structure with a poly(oligo-(ethylene glycol) methacrylate) backbone. The prodrug exhibited dual stimuli responsiveness and self-assembled into stable nanoparticles, which showed long-term circulation and enhanced cellular uptake. The nanoparticles demonstrated enhanced therapeutic effect and great hemocompatibility and biosafety. This strategy provides insights for the design of drug delivery carriers based on poly(oligo-(ethylene glycol) methacrylate).
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Multidisciplinary
Xiuli Zheng, Dayi Pan, Guonian Zhu, Lu Zhang, Apanpreet Bhamra, Rongjun Chen, Hu Zhang, Qiyong Gong, Zhongwei Gu, Kui Luo
Summary: This study developed pH/redox-responsive dendritic polymer-based nanoparticles (NPs) to enhance drug penetration and induce cell apoptosis through combination therapy. By amplifying the neighboring effect, the NPs were able to diffuse through the dense tumor extracellular matrix and penetrate solid tumors, effectively eradicating them.
ADVANCED MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Yechuan Zhang, Zhengxiang Gu, Seonho Yun, Kui Luo, Jingxiu Bi, Yan Jiao, Hu Zhang
Summary: In this study, a sustainable and effective structural modification strategy was proposed to improve drug loading capacity of Fe-based MOFs. The results showed that the approach of growing MIL-100 (Fe) on carboxylate-terminated polystyrene (PS-COOH) could significantly enhance drug loading capacity, with up to 30% loading capacity achieved. Cell viability tests and microscopy imaging further confirmed the potential of this method for breast cancer treatment.
Article
Engineering, Biomedical
Jiabin Zhang, Ming Zhang, Rongcai Lin, Yuguang Du, Liming Wang, Qingqiang Yao, Andrew Zannettino, Hu Zhang
Summary: Stem cell therapy using magnetic scaffolds has been developed to treat osteoarthritis. The magnetic scaffolds enhance chondrogenesis of mesenchymal stem cells through mechanical stimulation and magnetic field effects. The fiber topography of the scaffolds can be tuned with different coatings on magnetic nanoparticles, which selectively up-regulate chondrogenesis or osteogenesis-related genes.
Review
Chemistry, Multidisciplinary
Haonan Li, Qiang Luo, Hu Zhang, Xuelei Ma, Zhongwei Gu, Qiyong Gong, Kui Luo
Summary: This review provides a comprehensive overview of the applications of nanomedicine-assisted radio-immunotherapy, including the underlying working principles, design strategies, concerns over clinical translation, and perspectives.
CHEMICAL SOCIETY REVIEWS
(2023)
Review
Energy & Fuels
Pinar Karagoz, Sansanee Khiawjan, Marco P. C. Marques, Samir Santzouk, Timothy D. H. Bugg, Gary J. Lye
Summary: This review summarizes the valorization techniques of lignocellulosic biomass, with a focus on the extraction methods and pharmaceutical applications of lignin-derived materials. It discusses the potential of lignin-derived compounds in antimicrobial, antiviral, and antitumor activities, as well as their use in controlled drug delivery. Future research should focus on improving the availability and processing of lignocellulosic biomass, developing technologies for compound purification, enhancing process yield, and progressing to human clinical trials.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Engineering, Biomedical
Xueyang Xiao, Hao Cai, Qiaorong Huang, Bing Wang, Xiaoming Wang, Qiang Luo, Yinggang Li, Hu Zhang, Qiyong Gong, Xuelei Ma, Zhongwei Gu, Kui Luo
Summary: In this study, a dual-modality contrast agent, Gd-DOTA-TPBP, was successfully synthesized using an amphiphilic block polymer as a carrier. The contrast agent exhibited high resolution and sensitivity, making it a promising tool for early-stage tumor diagnosis.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Zhilin Li, Hao Cai, Zhiqian Li, Long Ren, Xuelei Ma, Hongyan Zhu, Qiyong Gong, Hu Zhang, Zhongwei Gu, Kui Luo
Summary: To improve the response rate of immune checkpoint inhibitors in immunosuppressive cancers, a self-amplified biomimetic nanosystem was constructed to induce immunogenic cell death at tumor sites. The nanosystem effectively reverses the immunosuppressive tumor microenvironment, leading to distinctive inhibition of tumor growth and metastasis when combined with immune checkpoint inhibitors.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Lei Gu, Zhenyu Duan, Xue Li, Xin Li, Yinggang Li, Xiaoling Li, Gang Xu, Peng Gao, Hu Zhang, Zhongwei Gu, Jie Chen, Qiyong Gong, Kui Luo
Summary: Emerging nanomedicines can eliminate cancer cells by promoting excessive intracellular reactive oxygen species (ROS) generation. However, tumor heterogeneity and poor penetration of nanomedicines often result in varying levels of ROS production, where low levels of ROS can actually promote tumor cell growth, reducing the effectiveness of these nanomedicines. In this study, a novel amphiphilic and block polymer-dendron conjugate-derived nanomedicine (GFLG-DP/Lap NPs) was developed, incorporating a photosensitizer (Ppa) for ROS therapy and Lapatinib (Lap) for molecular targeted therapy. By combining ROS therapy with Lap, the synergistic effect effectively kills cancer cells, even in deep tumor regions.
BIOACTIVE MATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Yiran Qu, Innocent Bekard, Ben Hunt, Jamie Black, Louis Fabri, Sally L. Gras, Sandra. E. Kentish
Summary: This study compares the performance of a nanofiber device and a resin column for antibody capture. The nanofiber device has a larger housing volume and lower binding capacity, but comparable eluate purity to the resin column. It shows high stability, can be used for multiple cycles, and maintains consistent eluate quality when scaled up. The use of a single nanofiber device can significantly reduce costs compared to a resin column, especially when the number of batches is limited.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Brandon Moore, Christos Georgakis, Chris Antoniou, Sarwat Khattak
Summary: Fed-batch cell culture processes are commonly used in biomanufacturing due to their simplicity and applicability in cGMP environments. However, the challenge lies in the changing physiochemical conditions within the bioreactor as the cell density changes. Traditional response surface models (RSMs) are commonly used for optimization but are limited by their use of time-invariant factors. Dynamic RSM (DRSM) models can predict the time-dependent impact of process inputs, allowing for optimization of process operations that change over time.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Lin Li, Yunfan Bai, Chuhua Qi, Yile Du, Xiaoxiao Ma, Yutong Li, Pingping Wu, Shuangli Chen, Sijing Zhang
Summary: A succinic anhydride-modified apple pomace (SAMAP) was synthesized to address environmental issues caused by the accumulation of apple pomace and effectively treat heavy metal ions. SAMAP exhibited high adsorption capacity for Cu(II) and Pb(II), suggesting its potential application in wastewater treatment.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Peter Satzer
Summary: Water for injection (WFI) production in the biopharmaceutical industry consumes excessive amounts of water and energy. Recycling buffers can potentially save up to 90% of resources, but achieving the full theoretical potential is impossible when a risk-aware design is used. Universal risk-based assessment is important for regulatory authorities to consider the implementation of such a strategy.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Gaoya Sun, Lingkai Jin, Guangxue Wang, Xiaoge Wang, Jin Huang
Summary: In this study, heterologous expression and homologous overexpression of ABC transporter proteins AatA and MdlB were found to improve butyric acid production in C. tyrobutyricum. The overexpression of these proteins upregulated the expression levels of key enzymes in the acetate synthesis pathway and promoted the synthesis and secretion of acetic acid. Additionally, the increase in ATPase activity facilitated sugar utilization, induced extracellular secretion of acetate, and shortened fermentation periods.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Taiki Okamura, Rina Aritomi, Takuya Matsumoto, Ryosuke Yamada, Hidehiko Hirakawa, Hiroyasu Ogino
Summary: In this study, proline was introduced to improve the stability of putidaredoxin reductase (PdR) in the Pseudomonas putida cytochrome P450 system. It was found that PdR_T221P had a longer half-life at high temperatures compared to wild-type PdR, but a shorter half-life in the presence of methanol. Molecular dynamics simulations supported these findings.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Yuying Hu, Xiaofan Wang, Shihao Zhang, Zimu Liu, Tengfang Hu, Xin Wang, Xiaoming Peng, Hongling Dai, Jing Wu, Fengping Hu
Summary: This study investigates the effect of iron-carbon micro-electrolysis (ICME) materials on high-solid anaerobic digestion (HSAD). The results show that ICME materials promote methane production in HSAD by increasing the attachment area of microorganisms and facilitating symbiotic metabolism of certain bacterial species. This study provides new insights into microbial mechanisms and enhances our understanding of ICME material enhancement in HSAD.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Jibao Liu, Yufeng Xu, Yuansong Wei
Summary: This study investigated the role of sludge rheology in anaerobic digestion (AD) and found that rheological properties increased with the increase of solid content, resulting in a negative effect on methane production. An extended ADM1 model revealed that enhanced sludge rheological properties increased mass diffusion resistance and reduced uptake rate of acetate.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Xiaoyan Liu, Zongze Chen, Dewen Kong, Xinying Zhang, Chuanhua Wang, Yongqi Wang
Summary: This study explored the role of intracellular and extracellular enzymes of Acinetobacter baumannii and Talaromyces sp. in the degradation of crude oil. The extracellular enzymes of Talaromyces sp. were more effective in degrading n-alkanes, while those of Acinetobacter baumannii had a better effect on aromatic hydrocarbons. The degradation enzyme systems of both bacteria and fungi complemented each other, improving the overall degradation ability.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Jing Dong, Lingli Xu, Yuxiang Liu, Li Ren, Ke Yuan
Summary: The utilization of biochar-immobilized microorganisms is an effective method for eliminating phenol from water. The high susceptibility of bacteria to environmental factors is a challenge for practical implementation. In this study, biochar was used to reduce microbial susceptibility and enhance phenol removal. The addition of biochar altered the dominant species of phenol-degrading bacteria and response surface analysis indicated the significant influence of biochar pyrolysis temperature and experimental temperature on phenol removal rate.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Zibin Pan, Mengying Liu, Zuliang Chen
Summary: This study successfully removed metalloids and heavy metals from acid mine drainage (AMD) using bio-synthesized Fe/Cu nanoparticles (Fe/Cu NPs). The Fe/Cu NPs showed high removal capacities and the presence of organic substances contributed to their stability.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Guangbing Liu, Han Zhang, Jincan Huang, Lu Zhang, Teng Zhang, Xuemin Yu, Weijing Liu, Chunkai Huang
Summary: This study investigated the effect of Fenton pre-treatment on the treatment efficiency of printing and dyeing wastewater (PDW) using two anaerobic/aerobic-membrane bioreactors (A/O-MBRs). The results showed that Fenton pre-treatment significantly improved the removal efficiency of COD and AOX in PDW, and reduced membrane fouling. The Shannon indices and metagenomics analysis indicated that the microbial diversity in anaerobic flocs was higher than that in aerobic flocs, and EC3.1.1.45 and pcaI were identified as key functional genes.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Lidia Borgosz, Duygu Dikicioglu
Summary: The Industrial Internet of Things (IIoT) is a system that connects devices and provides real-time insight into industrial processes. However, the complexity and regulatory requirements of the biomanufacturing sector make it challenging to implement IIoT. There is a need for universal solutions to overcome this challenge and advance the field of biomanufacturing.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Yajie Li, Weikang Kong, Yuyao Zhang, Huarui Zhou, Hongbo Liu, Salma Tabassum
Summary: In this study, the iron-carbon multi-micro electric field coupling anaerobic co-digestion technique was used to treat coal gasification wastewater (CGW). The experimental results showed that under optimal operating conditions, this technique can significantly reduce the toxicity of the wastewater and achieve high removal efficiencies. Additionally, the analysis of microbial communities revealed that the coupling system promotes direct interspecies electron transfer.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Aparecido Nivaldo Modenes, Debora Gozzi Fernandes, Daniela Estelita Goes Trigueros, Matheus Guilherme Amador, Fernando Rodolfo Espinoza-Quinones, Taysa de Souza Braniz, Adilson Ricken Schuelter, Glacy Jaqueline da Silva, Lucimar Pereira Bonett
Summary: This study aimed to systematically remove organic pollutants from raw dairy wastewater with high concentrations of COD, TOC, and TN using Poterioochromonas malhamensis algae strains. The results showed that the biomass yield rate using FP-PBRs was 10% higher than tubular PBRs, and the organic pollution in wastewater was significantly reduced with a decrease of about 98% in COD, 95% in TN, and 92% in TOC.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)