Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality

AhR sensing of bacterial pigments regulates antibacterial defence

(2014) Pedro Moura-Alves et al.   NATURE

ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells

(2014) Stephen J. Roper et al.   NUCLEIC ACIDS RESEARCH

Family-wide analysis of poly(ADP-ribose) polymerase activity

(2014) Sejal Vyas et al.   Nature Communications

The Glucocorticoid Receptor and KLF15 Regulate Gene Expression Dynamics and Integrate Signals through Feed-Forward Circuitry

(2013) S. K. Sasse et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of the Aryl Hydrocarbon Receptor Sensitizes Mice to Nonalcoholic Steatohepatitis by Deactivating Mitochondrial Sirtuin Deacetylase Sirt3

(2013) J. He et al.   MOLECULAR AND CELLULAR BIOLOGY

PARP-1 and gene regulation: Progress and puzzles

(2013) W. Lee Kraus et al.   MOLECULAR ASPECTS OF MEDICINE

Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation

(2013) Karla L. H. Feijs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases

(2013) Florian Rosenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Comparative Analysis of Temporal and Dose-Dependent TCDD-Elicited Gene Expression in Human, Mouse, and Rat Primary Hepatocytes

(2013) Agnes L. Forgacs et al.   TOXICOLOGICAL SCIENCES

Metabolomics Identifies an Inflammatory Cascade Involved in Dioxin- and Diet-Induced Steatohepatitis

(2012) Tsutomu Matsubara et al.   Cell Metabolism

The Role of PARP-1 and PARP-2 Enzymes in Metabolic Regulation and Disease

(2012) Péter Bai et al.   Cell Metabolism

Aryl Hydrocarbon Receptor Repressor (AhRR) Function Revisited: Repression of CYP1 Activity in Human Skin Fibroblasts Is Not Related to AhRR Expression

(2012) Julia Tigges et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

New PARP Gene with an Anti-Alphavirus Function

(2012) S. Atasheva et al.   JOURNAL OF VIROLOGY

2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation

(2012) Laura MacPherson et al.   NUCLEIC ACIDS RESEARCH

Aryl Hydrocarbon Receptor Activation in Hematopoietic Stem/Progenitor Cells Alters Cell Function and Pathway-Specific Gene Modulation Reflecting Changes in Cellular Trafficking and Migration

(2011) F. L. Casado et al.   MOLECULAR PHARMACOLOGY

Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis

(2011) Hong Lu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis

(2010) Jung Hoon Lee et al.   GASTROENTEROLOGY

Identification of the Aryl Hydrocarbon Receptor Target GeneTiPARPas a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect

(2010) Silvia Diani-Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice

(2010) Rucha Patel et al.   JOURNAL OF CLINICAL INVESTIGATION

PARP-1 Regulates Chromatin Structure and Transcription through a KDM5B-Dependent Pathway

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

(2010) Ellen L Goode et al.   NATURE GENETICS

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

(2009) Emily A. Stevens et al.   IMMUNOLOGY

The Active Form of Human Aryl Hydrocarbon Receptor (AHR) Repressor Lacks Exon 8, and Its Pro185 and Ala185 Variants Repress both AHR and Hypoxia-Inducible Factor

(2009) S. I. Karchner et al.   MOLECULAR AND CELLULAR BIOLOGY

The aryl hydrocarbon receptor in immunity

(2009) Charlotte Esser et al.   TRENDS IN IMMUNOLOGY

Regulation of constitutive and inducible AHR signaling: Complex interactions involving the AHR repressor

(2008) Mark E. Hahn et al.   BIOCHEMICAL PHARMACOLOGY

The single-macro domain protein LRP16 is an essential cofactor of androgen receptor

(2008) J Yang et al.   ENDOCRINE-RELATED CANCER

The PDGF signaling pathway controls multiple steroid-producing lineages

(2008) J. Schmahl et al.   GENES & DEVELOPMENT

Differential Activities of Cellular and Viral Macro Domain Proteins in Binding of ADP-Ribose Metabolites

(2008) Maarit Neuvonen et al.   JOURNAL OF MOLECULAR BIOLOGY

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

(2008) Fabio Marra et al.   TRENDS IN MOLECULAR MEDICINE

Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice

(2007) Tomonori Hosoya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS