Activation of the Aryl Hydrocarbon Receptor Sensitizes Mice to Nonalcoholic Steatohepatitis by Deactivating Mitochondrial Sirtuin Deacetylase Sirt3

The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression

(2012) Timothy V. Beischlag et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Nitrite activates AMP kinase to stimulate mitochondrial biogenesis independent of soluble guanylate cyclase

(2012) Li Mo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of oxidative stress in non-alcoholic steatohepatitis

(2011) G.H. Koek et al.   CLINICA CHIMICA ACTA

Febuxostat inhibition of endothelial-bound XO: Implications for targeting vascular ROS production

(2011) Umair Z. Malik et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

(2011) Anabela P. Rolo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Peroxisome Proliferator-activated Receptor-γ Coactivator-1α Controls Transcription of theSirt3Gene, an Essential Component of the Thermogenic Brown Adipocyte Phenotype

(2011) Albert Giralt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis

(2011) Hong Lu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis

(2010) Jung Hoon Lee et al.   GASTROENTEROLOGY

Identification of the Aryl Hydrocarbon Receptor Target GeneTiPARPas a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect

(2010) Silvia Diani-Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Constitutive Androstane Receptor Is an Anti-obesity Nuclear Receptor That Improves Insulin Sensitivity

(2009) Jie Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management

(2008) Raj Vuppalanchi et al.   HEPATOLOGY

Non-alcoholic steatohepatitis and animal models: Understanding the human disease

(2008) Marta Varela-Rey et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

(2008) Fabio Marra et al.   TRENDS IN MOLECULAR MEDICINE

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY