Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage

Association Analysis of IGF2BP2, KCNJ11, and CDKAL1 Polymorphisms with Type 2 Diabetes Mellitus in a Moroccan Population: A Case–Control Study and Meta-analysis

(2014) Houda Benrahma et al.   BIOCHEMICAL GENETICS

Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy

(2014) Zhiyu Wang et al.   Cell Metabolism

VHL-mediated disruption of Sox9 activity compromises  -cell identity and results in diabetes mellitus

(2013) S. Puri et al.   GENES & DEVELOPMENT

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome

(2013) A. C. Nica et al.   GENOME RESEARCH

Inactivation of specific β cell transcription factors in type 2 diabetes

(2013) Shuangli Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of FOXO1 in β-cell failure and type 2 diabetes mellitus

(2013) Tadahiro Kitamura   Nature Reviews Endocrinology

Restoration of the Unfolded Protein Response in Pancreatic   Cells Protects Mice Against Type 1 Diabetes

(2013) F. Engin et al.   Science Translational Medicine

The role of the unfolded protein response in diabetes mellitus

(2013) Takao Iwawaki et al.   Seminars in Immunopathology

Association of Variants in PPARγ2, IGF2BP2, and KCNQ1 with a Susceptibility to Gestational Diabetes Mellitus in a Korean Population

(2013) Seung Joo Chon et al.   YONSEI MEDICAL JOURNAL

β-cell dedifferentiation in diabetes is important, but what is it?

(2013) Gordon C Weir et al.   Islets

Endoplasmic Reticulum Stress and Type 2 Diabetes

(2012) Sung Hoon Back et al.   Annual Review of Biochemistry

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Failure of the Adaptive Unfolded Protein Response in Islets of Obese Mice Is Linked With Abnormalities in  -Cell Gene Expression and Progression to Diabetes

(2012) J. Y. Chan et al.   DIABETES

Islet  -Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model

(2012) S. A. Tersey et al.   DIABETES

Insulin resistance and cancer: the role of insulin and IGFs

(2012) Sefirin Djiogue et al.   ENDOCRINE-RELATED CANCER

Effects of long-term treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin on islet endocrine cells in non-obese type 2 diabetic Goto-Kakizaki rats

(2012) Wataru Inaba et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets

(2012) Luisa Martino et al.   PLoS One

Autophagy: for better or for worse

(2011) Ellen Wirawan et al.   CELL RESEARCH

mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry

(2011) N. Dai et al.   GENES & DEVELOPMENT

Research Resource: New and Diverse Substrates for the Insulin Receptor Isoform A Revealed by Quantitative Proteomics After Stimulation With IGF-II or Insulin

(2011) Alaide Morcavallo et al.   MOLECULAR ENDOCRINOLOGY

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

(2010) F. Allagnat et al.   DIABETOLOGIA

Glucagon-Like Peptide-1 Protects  -Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop

(2009) M. Cornu et al.   DIABETES

Towards better understanding of the contributions of overwork and glucotoxicity to the β-cell inadequacy of type 2 diabetes

(2009) G. C. Weir et al.   DIABETES OBESITY & METABOLISM

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

β-cell failure as a complication of diabetes

(2008) K. J. Chang-Chen et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS