Alteration of Lysosome Fusion and Low-grade Inflammation Mediated by Super-low-dose Endotoxin

Induction of Lysosomal Biogenesis in Atherosclerotic Macrophages Can Rescue Lipid-Induced Lysosomal Dysfunction and Downstream Sequelae

(2014) Roy Emanuel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family

(2014) Kefeng Lu et al.   CELL

The ULK1 complex

(2013) Pui-Mun Wong et al.   Autophagy

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

Autophagy and human diseases

(2013) Peidu Jiang et al.   CELL RESEARCH

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

(2013) Devin M. Wolfe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Ubiquitin Interacts with the Tollip C2 and CUE Domains and Inhibits Binding of Tollip to Phosphoinositides

(2013) Sharmistha Mitra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway

(2013) Daniel H. Madsen et al.   JOURNAL OF CELL BIOLOGY

Regulation of Mammalian Autophagy by Class II and III PI 3-Kinases through PI3P Synthesis

(2013) Kelly Devereaux et al.   PLoS One

Role of Toll-Interacting Protein Gene Polymorphisms in Leprosy Mexican Patients

(2013) Margarita Montoya-Buelna et al.   Biomed Research International

Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study

(2013) Imre Noth et al.   Lancet Respiratory Medicine

Human TOLLIP Regulates TLR2 and TLR4 Signaling and Its Polymorphisms Are Associated with Susceptibility to Tuberculosis

(2012) J. A. Shah et al.   JOURNAL OF IMMUNOLOGY

Rescue of Dysfunctional Autophagy Attenuates Hyperinflammatory Responses from Cystic Fibrosis Cells

(2012) M. L. Mayer et al.   JOURNAL OF IMMUNOLOGY

Molecular Mechanisms Responsible for the Selective and Low-Grade Induction of Proinflammatory Mediators in Murine Macrophages by Lipopolysaccharide

(2012) U. Maitra et al.   JOURNAL OF IMMUNOLOGY

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

(2012) David A. Tumbarello et al.   NATURE CELL BIOLOGY

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

(2012) N. Jaber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Related Oxidative Stress Compromises Endosomal Proteostasis

(2012) Elvira S. Cannizzo et al.   Cell Reports

Molecular Mechanisms and Pathological Consequences of Endotoxin Tolerance and Priming

(2011) Matthew Morris et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Autophagy Dysregulation in Amyotrophic Lateral Sclerosis

(2011) Sheng Chen et al.   BRAIN PATHOLOGY

AMPK Activates Autophagy by Phosphorylating ULK1

(2011) Kai Mao et al.   CIRCULATION RESEARCH

Bacterial Endotoxin Activity in Human Serum Is Associated With Dyslipidemia, Insulin Resistance, Obesity, and Chronic Inflammation

(2011) Mariann I. Lassenius et al.   DIABETES CARE

Dysfunctions in endosomal–lysosomal and autophagy pathways underlie neuropathology in a mouse model for Lafora disease

(2011) Rajat Puri et al.   HUMAN MOLECULAR GENETICS

Ehrlichia chaffeensis Induces Monocyte Inflammatory Responses through MyD88, ERK, and NF-κB but Not through TRIF, Interleukin-1 Receptor 1 (IL-1R1)/IL-18R1, or Toll-Like Receptors

(2011) Koshiro Miura et al.   INFECTION AND IMMUNITY

Tollip: a multitasking protein in innate immunity and protein trafficking

(2011) Daniel G.S. Capelluto   MICROBES AND INFECTION

Type 2 Diabetes Is Associated with Altered NF-κB DNA Binding Activity, JNK Phosphorylation, and AMPK Phosphorylation in Skeletal Muscle after LPS

(2011) Anne Sofie Andreasen et al.   PLoS One

Dysregulation of autophagy and Parkinson’s disease: the MEF2D link

(2010) Qian Yang et al.   APOPTOSIS

Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotein Cooperatively Activate Macrophages via Nuclear Factor κB and Activator Protein-1

(2010) Philipp Wiesner et al.   CIRCULATION RESEARCH

Negative Regulation of Vps34 by Cdk Mediated Phosphorylation

(2010) Tsuyoshi Furuya et al.   MOLECULAR CELL

Lysosomal Storage Disease: Revealing Lysosomal Function and Physiology

(2010) Emma J. Parkinson-Lawrence et al.   PHYSIOLOGY

Regulation of membrane biogenesis in autophagy via PI3P dynamics

(2010) Takeshi Noda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-β-dependent pathways and increases expression of negative regulators of TLR signaling

(2009) Wenji Piao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

An Innate Immunity Signaling Process Suppresses Macrophage ABCA1 Expression through IRAK-1-Mediated Downregulation of Retinoic Acid Receptor   and NFATc2

(2009) U. Maitra et al.   MOLECULAR AND CELLULAR BIOLOGY

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling inDrosophila

(2008) Gábor Juhász et al.   JOURNAL OF CELL BIOLOGY