SIRT1-related inhibition of pro-inflammatory responses and oxidative stress are involved in the mechanism of nonspecific low back pain relief after exercise through modulation of Toll-like receptor 4

The global burden of low back pain: estimates from the Global Burden of Disease 2010 study

(2014) Damian Hoy et al.   ANNALS OF THE RHEUMATIC DISEASES

Effect of exercise training on skeletal muscle cytokine expression in the elderly

(2014) Paul A. Della Gatta et al.   BRAIN BEHAVIOR AND IMMUNITY

Caught in the cross fire: p53 in inflammation

(2014) Tomer Cooks et al.   CARCINOGENESIS

Regulation of Akt Signaling by Sirtuins

(2014) Vinodkumar B. Pillai et al.   CIRCULATION RESEARCH

Association between baseline IL-6 and 1-year recovery in lumbar radicular pain

(2014) E.I. Schistad et al.   EUROPEAN JOURNAL OF PAIN

Swertiamarin attenuates inflammation mediators via modulating NF-κB/I κB and JAK2/STAT3 transcription factors in adjuvant induced arthritis

(2014) S. Saravanan et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Low Back Pain

(2014) Anna L. Golob et al.   MEDICAL CLINICS OF NORTH AMERICA

Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis

(2014) Fanlei Hu et al.   PLoS One

The Effectiveness of Pilates Exercise in People with Chronic Low Back Pain: A Systematic Review

(2014) Cherie Wells et al.   PLoS One

Toll-like receptor-4 signaling: a new potential therapeutic pathway for rheumatoid arthritis

(2014) Xiaofeng Li et al.   RHEUMATOLOGY INTERNATIONAL

Current overview of functions of FoxO proteins, with special regards to cellular homeostasis, cell response to stress, as well as inflammation and aging

(2013) M Wątroba et al.   Advances in Medical Sciences

Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice

(2013) Eun-Bum Kang et al.   APOPTOSIS

SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-κB pathway

(2013) L. Cao et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Redox-regulating sirtuins in aging, caloric restriction, and exercise

(2013) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

(2013) Antero Salminen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Treadmill exercise and wheel exercise enhance expressions of neutrophic factors in the hippocampus of lipopolysaccharide-injected rats

(2013) Sung-Eun Kim et al.   NEUROSCIENCE LETTERS

Back Pain in Adults

(2013) Jonathan A. Becker et al.   PRIMARY CARE

Functional crosstalk of PGC-1 coactivators and inflammation in skeletal muscle pathophysiology

(2013) Petra S. Eisele et al.   Seminars in Immunopathology

Sirtuins: from metabolic regulation to brain aging

(2013) Wenzhen Duan   Frontiers in Aging Neuroscience

Sirtuins in neurodegenerative diseases: an update on potential mechanisms

(2013) Sang-Won Min et al.   Frontiers in Aging Neuroscience

Core Stabilization Exercise Prescription, Part 2

(2013) Jason Brumitt et al.   Sports Health-A Multidisciplinary Approach

SIRT1 and energy metabolism

(2012) X. Li   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training

(2012) Erika Koltai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Oxygen Consumption and Usage During Physical Exercise: The Balance Between Oxidative Stress and ROS-Dependent Adaptive Signaling

(2012) Zsolt Radak et al.   ANTIOXIDANTS & REDOX SIGNALING

Manual therapy followed by specific active exercises versus a placebo followed by specific active exercises on the improvement of functional disability in patients with chronic non specific low back pain: a randomized controlled trial

(2012) Pierre Balthazard et al.   BMC MUSCULOSKELETAL DISORDERS

A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis

(2011) Michael Yellin et al.   ARTHRITIS AND RHEUMATISM

The biochemical response to biomechanical tissue loading on the low back during physical work exposure

(2011) Gang Yang et al.   CLINICAL BIOMECHANICS

Chemerin induces CCL2 and TLR4 in synovial fibroblasts of patients with rheumatoid arthritis and osteoarthritis

(2011) Kristina Eisinger et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Sirtuins, Aging, and Medicine

(2011) Leonard Guarente   NEW ENGLAND JOURNAL OF MEDICINE

The Red Wine Polyphenol Resveratrol Shows Promising Potential for the Treatment of Nucleus Pulposus–Mediated Pain In Vitro and In Vivo

(2011) Karin Wuertz et al.   SPINE

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress

(2010) T. T. Schug et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

(2009) Takeshi Yoshizaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-κB nuclear signalling in dorsal root ganglia

(2009) Giuseppe D'Agostino et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

(2009) Erika Koltai et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Sirtuin family: therapeutic targets to treat diseases of aging

(2008) Jill C Milne et al.   CURRENT OPINION IN CHEMICAL BIOLOGY