Drug-induced macrophage autophagy in atherosclerosis: for better or worse?

Everolimus Triggers Cytokine Release by Macrophages

(2012) Wim Martinet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

FTY720-induced blockage of autophagy enhances anticancer efficacy of milatuzumab in mantle cell lymphoma

(2012) Lapo Alinari et al.   Autophagy

Autophagic cell death exists

(2012) Peter G.H. Clarke et al.   Autophagy

The end of autophagic cell death?

(2012) Shensi Shen et al.   Autophagy

Molecular and cellular mechanisms of macrophage survival in atherosclerosis

(2012) Wim Martinet et al.   BASIC RESEARCH IN CARDIOLOGY

Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques

(2012) Inge Meyer et al.   BASIC RESEARCH IN CARDIOLOGY

Autophagy Links Inflammasomes to Atherosclerotic Progression

(2012) Babak Razani et al.   Cell Metabolism

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

(2012) Xianghai Liao et al.   Cell Metabolism

Autophagy induced by FTY720 promotes apoptosis in U266 cells

(2012) Aijun Liao et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IFN-  Elicits Macrophage Autophagy via the p38 MAPK Signaling Pathway

(2012) T. Matsuzawa et al.   JOURNAL OF IMMUNOLOGY

Autophagy in Atherosclerosis

(2011) Dorien M. Schrijvers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages

(2011) Goran Petrovski et al.   Autophagy

FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death

(2011) L. Alinari et al.   BLOOD

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

A dual role for Ca2+ in autophagy regulation

(2011) Jean-Paul Decuypere et al.   CELL CALCIUM

Cell death by autophagy: facts and apparent artefacts

(2011) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Inhibition of human in-stent restenosis: a molecular view

(2011) Arturo Giordano et al.   CURRENT OPINION IN PHARMACOLOGY

Antirestenotic Mechanisms of Everolimus on Human Coronary Artery Smooth Muscle Cells

(2011) Mark C. Lavigne et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Autophagy and disease: always two sides to a problem

(2011) Sunandini Sridhar et al.   JOURNAL OF PATHOLOGY

Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells

(2010) Kun L. Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy Signaling Through Reactive Oxygen Species

(2010) Ju Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

Cell Death–Mediated Cleavage of the Attraction Signal p43 in Human Atherosclerosis

(2010) Wim Martinet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy

(2010) Ning Zhang et al.   Autophagy

The autophagy-lysosome pathway: A novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells

(2010) Yan-lin Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques

(2010) Inge De Meyer et al.   BRITISH JOURNAL OF PHARMACOLOGY

HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs

(2010) C Muller et al.   CELL DEATH AND DIFFERENTIATION

Intracoronary Optical Coherence Tomography and Histology at 1 Month and 2, 3, and 4 Years After Implantation of Everolimus-Eluting Bioresorbable Vascular Scaffolds in a Porcine Coronary Artery Model

(2010) Yoshinobu Onuma et al.   CIRCULATION

Sphingosine-1-Phosphate Receptor 3 Promotes Recruitment of Monocyte/Macrophages in Inflammation and Atherosclerosis

(2010) Petra Keul et al.   CIRCULATION RESEARCH

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

(2010) Valérie Vingtdeux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis

(2010) B. Y. K. Law et al.   MOLECULAR CANCER THERAPEUTICS

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

mTORC1 signaling: what we still don't know

(2010) X. Wang et al.   Journal of Molecular Cell Biology

ADRP/ADFP and Mal1 expression are increased in macrophages treated with TLR agonists

(2009) Kenneth R. Feingold et al.   ATHEROSCLEROSIS

Autophagy in Atherosclerosis

(2009) Wim Martinet et al.   CIRCULATION RESEARCH

Autophagy in disease: a double-edged sword with therapeutic potential

(2009) Wim Martinet et al.   CLINICAL SCIENCE

The Protein Synthesis Inhibitor Anisomycin Induces Macrophage Apoptosis in Rabbit Atherosclerotic Plaques through p38 Mitogen-Activated Protein Kinase

(2009) V. Croons et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods

(2009) Patrick W Serruys et al.   LANCET

Everolimus, a promising medical therapy for coronary heart disease?

(2009) Lei Jia et al.   MEDICAL HYPOTHESES

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells

(2008) Bradford G. Hill et al.   BIOCHEMICAL JOURNAL

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

(2008) S Sarkar et al.   CELL DEATH AND DIFFERENTIATION

Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

(2008) S. H. Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy in atherosclerosis

(2008) Wim Martinet et al.   Current Atherosclerosis Reports

mTOR Pathway and mTOR Inhibitors as Agents for Cancer Therapy

(2008) Paolo Baldo et al.   CURRENT CANCER DRUG TARGETS

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages

(2008) Chong-Shan Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Everolimus Inhibits Monocyte/Macrophage Migration in Vitro and Their Accumulation in Carotid Lesions of Cholesterol-Fed Rabbits

(2008) R. Baetta et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR−/− mice despite severe hypercholesterolemia

(2007) Marc A. Mueller et al.   ATHEROSCLEROSIS