New genetic and physiological factors for excessive erythrocytosis and Chronic Mountain Sickness

Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction

(2015) Colleen Glyde Julian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy

(2015) Rong Cai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Chronic mountain sickness in Chinese Han males who migrated to the Qinghai-Tibetan plateau: application and evaluation of diagnostic criteria for chronic mountain sickness

(2014) Chunhua Jiang et al.   BMC PUBLIC HEALTH

Hypoxia-Induced SUMOylation of E3 Ligase HAF Determines Specific Activation of HIF2 in Clear-Cell Renal Cell Carcinoma

(2014) M. Y. Koh et al.   CANCER RESEARCH

Prevalence, Clinical Profile, Iron Status, and Subject-Specific Traits for Excessive Erythrocytosis in Andean Adults Living Permanently at 3,825 Meters Above Sea Level

(2014) Aldo De Ferrari et al.   CHEST

Genetic Variation in SENP1 and ANP32D as Predictors of Chronic Mountain Sickness

(2014) Amy M. Cole et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Decreased plasma soluble erythropoietin receptor in high-altitude excessive erythrocytosis and Chronic Mountain Sickness

(2014) Francisco C. Villafuerte et al.   JOURNAL OF APPLIED PHYSIOLOGY

SUMO1 enhances cAMP-dependent exocytosis and glucagon secretion from pancreatic α-cells

(2014) Xiao-Qing Dai et al.   JOURNAL OF PHYSIOLOGY-LONDON

Important Role of SUMOylation of Spliceosome Factors in Prostate Cancer Cells

(2014) Donghua Wen et al.   JOURNAL OF PROTEOME RESEARCH

The Genetic Basis of Chronic Mountain Sickness

(2014) Roy Ronen et al.   PHYSIOLOGY

SUMO-specific protease 1 modulates cadmium-augmented transcriptional activity of androgen receptor (AR) by reversing AR SUMOylation

(2014) Ruiqin Wu et al.   TOXICOLOGY LETTERS

Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders

(2013) Dan Zhou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sleep-disordered breathing and oxidative stress in preclinical chronic mountain sickness (excessive erythrocytosis)

(2013) Colleen Glyde Julian et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Two new mutations in the HIF2A gene associated with erythrocytosis

(2012) Melanie J. Percy et al.   AMERICAN JOURNAL OF HEMATOLOGY

Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation

(2012) Hany A Abdel-Hafiz et al.   BMC MOLECULAR BIOLOGY

CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-α

(2012) S Li et al.   ONCOGENE

Hypoxia-Induced Alternative Splicing in Endothelial Cells

(2012) Julia E. Weigand et al.   PLoS One

The HIF Pathway and Erythrocytosis

(2011) Frank S. Lee et al.   Annual Review of Pathology-Mechanisms of Disease

Induction of SENP1 in Endothelial Cells Contributes to Hypoxia-driven VEGF Expression and Angiogenesis

(2010) Ying Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis

(2010) Luyang Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Soluble Erythropoietin Receptor Contributes to Erythropoietin Resistance in End-Stage Renal Disease

(2010) Eliyahu V. Khankin et al.   PLoS One

Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders

(2010) C. M. Beall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Evidence for High-Altitude Adaptation in Tibet

(2010) T. S. Simonson et al.   SCIENCE

Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude

(2010) X. Yi et al.   SCIENCE

High serum testosterone levels are associated with excessive erythrocytosis of chronic mountain sickness in men

(2009) Gustavo F. Gonzales et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Impaired acclimatization to chronic hypoxia in adult male and female rats following neonatal hypoxia

(2009) Delphine Lumbroso et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cre recombinase expression controlled by the hematopoietic regulatory domain of Gata-1 is erythroid-specific

(2008) Donghoon Yoon et al.   BLOOD CELLS MOLECULES AND DISEASES

Gene Expression in Chronic High Altitude Diseases

(2008) Fabiola León-Velarde et al.   HIGH ALTITUDE MEDICINE & BIOLOGY