P2X7Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the NLRP3/ASC/Caspase 1 Pathway

P2X7 receptor activation induces inflammatory responses in salivary gland epithelium

(2012) Lucas T. Woods et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IL-17: A new actor in IFN-driven systemic autoimmune diseases

(2012) Aurélie Ambrosi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-17 Cytokines Are Critical in Development of Fatal Lupus Glomerulonephritis

(2012) Prapaporn Pisitkun et al.   IMMUNITY

U1-Small Nuclear Ribonucleoprotein Activates the NLRP3 Inflammasome in Human Monocytes

(2012) M. S. Shin et al.   JOURNAL OF IMMUNOLOGY

TLR Agonists Stimulate Nlrp3-Dependent IL-1  Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo

(2012) Y. He et al.   JOURNAL OF IMMUNOLOGY

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

The machinery of Nod-like receptors: refining the paths to immunity and cell death

(2011) Maya Saleh   IMMUNOLOGICAL REVIEWS

Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus

(2011) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

Inhibition of Neuronal Voltage-Gated Sodium Channels by Brilliant Blue G

(2011) S. Jo et al.   MOLECULAR PHARMACOLOGY

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

(2011) E. Mezzaroma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-α accelerates murine systemic lupus erythematosus in a T cell-dependent manner

(2010) Zheng Liu et al.   ARTHRITIS AND RHEUMATISM

The NZM2410-derived lupus susceptibility locus Sle2c1 increases Th17 polarization and induces nephritis in fas-deficient mice

(2010) Zhiwei Xu et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1  Produced in Response to Islet Autoantigen Presentation Differentiates T-Helper 17 Cells at the Expense of Regulatory T-Cells: Implications for the Timing of Tolerizing Immunotherapy

(2010) S. Bertin-Maghit et al.   DIABETES

Inflammasome-independent Role of Apoptosis-associated Speck-like Protein Containing a CARD (ASC) in T Cell Priming Is Critical for Collagen-induced Arthritis

(2010) Sirish K. Ippagunta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in Apoptotic Gene Expression in Lymphocytes from Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Compared with Healthy Lymphocytes

(2010) Paul Eggleton et al.   JOURNAL OF CLINICAL IMMUNOLOGY

IL-1 -Mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17-Producing Cells

(2010) L. Li et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Critical Role for PYCARD/ASC in the Development of Experimental Autoimmune Encephalomyelitis

(2010) P. J. Shaw et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-23 Receptor Deficiency Prevents the Development of Lupus Nephritis in C57BL/6-lpr/lpr Mice

(2010) V. C. Kyttaris et al.   JOURNAL OF IMMUNOLOGY

Adenosine 2A receptor is protective against renal injury in MRL/lpr mice

(2010) L Zhang et al.   LUPUS

Proinflammatory T helper type 17 cells are effective B-cell helpers

(2010) M. Mitsdoerffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD3 mAb treatment ameliorated the severity of the cGVHD-induced lupus nephritis in mice by up-regulation of Foxp3+ regulatory T cells in the target tissue: Kidney

(2010) Ji-Lu Zhang et al.   TRANSPLANT IMMUNOLOGY

Long-term mortality and renal outcome in a cohort of 100 patients with Lupus Nephritis

(2010) Mikkel Faurschou et al.   ARTHRITIS CARE & RESEARCH

Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus

(2009) Luis E. Muñoz et al.   ARTHRITIS AND RHEUMATISM

Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis

(2009) Y. Wang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration

(2009) Miguel Díaz-Hernández et al.   FASEB JOURNAL