The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis

Transcriptomics of Wild-Type Mice and Mice Lacking ADAMTS-5 Activity Identifies Genes Involved in Osteoarthritis Initiation and Cartilage Destruction

(2013) John F. Bateman et al.   ARTHRITIS AND RHEUMATISM

Clock Genes Influence Gene Expression in Growth Plate and Endochondral Ossification in Mice

(2012) Takeshi Takarada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

(2012)   LANCET

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Cold-Inducible RNA-Binding Protein Modulates Circadian Gene Expression Posttranscriptionally

(2012) J. Morf et al.   SCIENCE

Identification of Small Molecule Activators of Cryptochrome

(2012) T. Hirota et al.   SCIENCE

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF

(2012) Stefanie Haas et al.   ARTHRITIS RESEARCH & THERAPY

Adaptive Temperature Compensation in Circadian Oscillations

(2012) Paul François et al.   PLoS Computational Biology

Brain-Specific Rescue of Clock Reveals System-Driven Transcriptional Rhythms in Peripheral Tissue

(2012) Michael E. Hughes et al.   PLoS Genetics

Circadian Rhythm and Cartilage Extracellular Matrix Genes in Osseointegration: A Genome-Wide Screening of Implant Failure by Vitamin D Deficiency

(2011) Cristiane Machado Mengatto et al.   PLoS One

Serum factors in older individuals change cellular clock properties

(2011) L. Pagani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

(2011) Guillaume Rey et al.   PLOS BIOLOGY

A Circadian Clock Is Not Required in an Arctic Mammal

(2010) Weiqun Lu et al.   CURRENT BIOLOGY

Novel Therapies in OA

(2010) Carl R. Flannery   CURRENT DRUG TARGETS

JTK_CYCLE: An Efficient Nonparametric Algorithm for Detecting Rhythmic Components in Genome-Scale Data Sets

(2010) Michael E. Hughes et al.   JOURNAL OF BIOLOGICAL RHYTHMS

The Clock Genes Period 2 and Cryptochrome 2 Differentially Balance Bone Formation

(2010) Erik Maronde et al.   PLoS One

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

(2010) E. D. Buhr et al.   SCIENCE

Mammalian Clock Gene Cryptochrome Regulates Arthritis via Proinflammatory Cytokine TNF- 

(2009) A. Hashiramoto et al.   JOURNAL OF IMMUNOLOGY

Degradome expression profiling in human articular cartilage

(2009) Tracey E Swingler et al.   ARTHRITIS RESEARCH & THERAPY

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

fdrtool: a versatile R package for estimating local and tail area-based false discovery rates

(2008) K. Strimmer   BIOINFORMATICS

Articular cartilage: structure, injuries and review of management

(2008) A. M. Bhosale et al.   BRITISH MEDICAL BULLETIN

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS