U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells
出版年份 2014 全文链接
标题
U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells
作者
关键词
Cytochrome P450, CYP3A4, Gene regulation, Pregnane X receptor, ERK cascade
出版物
ARCHIVES OF TOXICOLOGY
Volume 88, Issue 12, Pages 2243-2259
出版商
Springer Nature
发表日期
2014-05-13
DOI
10.1007/s00204-014-1254-2
参考文献
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