Review
Surgery
Gang Yang, Guan Wang, Ji Sun, Yongfu Xiong, Weinan Li, Tao Tang, Jingdong Li
Summary: Although hepatic resection is the standard treatment for colorectal cancer liver metastases patients, radiofrequency ablation may serve as an alternative for elderly or vulnerable patients. The study showed that patients undergoing radiofrequency ablation had higher recurrence rates and poorer long-term survival outcomes compared to hepatic resection. Factors such as tumor size, multiple tumors, age, primary node positivity, and metachronous metastasis were found to independently influence survival.
INTERNATIONAL JOURNAL OF SURGERY
(2021)
Review
Gastroenterology & Hepatology
Paschalis Gavriilidis, Keith J. Roberts, Nicola de'Angelis, Luca Aldrighetti, Robert P. Sutcliffe
Summary: This study compared the recurrence rate and survival benefit of microwave ablation, radiofrequency ablation, and hepatic resection in colorectal liver metastases through the first network meta-analysis. The results showed that hepatic resection had lower local recurrence rate and better disease-free and overall survival compared to the other two methods. For resectable CRLM, hepatic resection remains the treatment of choice.
HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
(2021)
Article
Surgery
Rodrigo Blanco Dumarco, Gilton Marques Fonseca, Fabricio Ferreira Coelho, Vagner Birk Jeismann, Fabio Ferrari Makdissi, Jaime Arthur Pirolla Kruger, Sergio Carlos Nahas, Paulo Herman
Summary: This study evaluated the outcomes and prognostic factors for patients with >= 4 colorectal liver metastases who underwent liver resection. The results showed that despite tumor recurrence, a significant number of patients experienced long-term survival, indicating the chronic nature of the disease.
Article
Radiology, Nuclear Medicine & Medical Imaging
Seong Eun Ko, Min Woo Lee, Soohyun Ahn, Hyunchul Rhim, Tae Wook Kang, Kyoung Doo Song, Jong Man Kim, Gyu-Seong Choi, Dong Ik Cha, Ji Hye Min, Dong Hyun Sinn, Moon Seok Choi, Hyo Keun Lim
Summary: This study compared the therapeutic outcomes of laparoscopic hepatic resection (LHR) and laparoscopic radiofrequency ablation (LRFA) for single subcapsular hepatocellular carcinoma (HCC) measuring 1-3 cm. The results showed no significant difference in therapeutic outcomes between the two methods.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Article
Oncology
Yang Huang, Liangliang Xu, Min Huang, Li Jiang, Mingqing Xu
Summary: This study compared the long-term outcomes of patients with recurrent and multifocal hepatocellular carcinoma (HCC) meeting the Barcelona Clinic Liver Cancer (BCLC) stage A who underwent repeat hepatectomy (RH) or RH combined with intraoperative radiofrequency ablation (RFA). The results showed no significant difference in overall survival and recurrence-free survival between the two treatment groups. However, for patients whose tumors were located in the same lobe, RH alone was associated with better recurrence-free survival than combination treatment.
Article
Oncology
Mariana I. Chavez, Sepideh Gholami, Bradford J. Kim, Georgios A. Margonis, Cecilia G. Ethun, Susan Tsai, Kathleen K. Christians, Callisia Clarke, Harveshp Mogal, Shishir K. Maithel, Timothy M. Pawlik, Michael I. D'Angelica, Thomas A. Aloia, Daniel Eastwood, T. Clark Gamblin
Summary: This study is the largest TSH series in the US and demonstrates evidence of safety and feasibility in the management of bilateral CRLM. Outcomes are influenced by margin status and operative estimated blood loss (EBL).
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
T. W. van de Geest, M. J. van Amerongen, P. M. H. Nierop, D. J. Hoppener, D. J. Grunhagen, A. Moelker, J. J. Futterer, C. Verhoef, J. H. W. de Wilt
Summary: This study compared the recurrence rate and oncological survival of patients with colorectal liver metastases treated with radiofrequency ablation (RFA) or surgery. After propensity score matching, RFA showed lower complications and similar survival rates to surgical resection, suggesting it can be a good alternative treatment for patients who are not suitable for surgery.
Article
Surgery
Nozomu Sakai, Koichi Hayano, Takashi Mishima, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Yohei Kawasaki, Hisahiro Matsubara, Masayuki Ohtsuka
Summary: This study found a significant association between the fat signal fraction assessed with MRI and hepatic recurrence following initial hepatectomy for CRLM.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Review
Surgery
Bao-Hong Yuan, Yan-Kun Zhu, Xu-Ming Zou, Hao-Dong Zhou, Ru-Hong Li, Jian-Hong Zhong
Summary: A systematic review and meta-analysis showed that repeat hepatic resection based on radio- or microwaves has similar overall survival rates compared to ablation in patients with recurrent hepatocellular carcinoma. However, ablation was associated with lower perioperative morbidity rates.
Review
Surgery
Seong Wook Shin, Keun Soo Ahn, Sang Woo Kim, Tae-Seok Kim, Yong Hoon Kim, Koo Jeong Kang
Summary: This study found that liver resection (LR) is more effective than local ablation therapies (such as RFA, MWA, and RFA plus TACE) in treating HCC within the Milan criteria. Specifically, LR has better 5-year recurrence-free survival and lower local recurrence rates compared to local ablation therapies.
Article
Multidisciplinary Sciences
Xinyuan Zhang, Yujing Xin, Yi Chen, Xiang Zhou
Summary: This meta-analysis evaluates the prognostic role of albumin-to-alkaline phosphatase ratio (AAPR) in hepatocellular carcinoma (HCC) patients. Data from 12 cohorts totaling 2634 patients were analyzed, and the results demonstrate that lower AAPR predicts inferior overall survival and recurrence-free survival rates. Despite some heterogeneity and publication bias, subgroup and sensitivity analyses confirm the association between AAPR and survival outcomes. These findings suggest that AAPR holds promise as a prognostic indicator for HCC.
SCIENTIFIC REPORTS
(2023)
Article
Oncology
Yana Zhai, Weijun Bai, Jin Zhou, Qian Dong, Jingdong Zhang
Summary: This study assessed the impact of size differences of multiple liver metastases on liver recurrence-free survival in patients with colorectal liver metastases. The results showed that TSR is an accurate prognostic tool and can further stratify patients into different risk groups.
Article
Surgery
Ye Zhang, Kai Wang, Jie Liu, Siyuan Xu, Yu Sun, Meng Xu, Xiaolei Wang
Summary: This study retrospectively enrolled 97 patients with thyroid carcinoma and explored the clinical features, diagnosis, surgical treatment, and outcomes of parapharyngeal lymph node metastases. The results showed that surgical resection through the transcervical approach was effective and safe, with possible postoperative neurological side effects. Parapharyngeal lymph node metastasis was associated with distant metastases and poor prognosis.
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyun Jae Lee, Min Woo Lee, Soo Hyun Ahn, Dong Ik Cha, Seong Eun Ko, Tae Wook Kang, Kyoung Doo Song, Hyunchul Rhim
Summary: This study evaluated local tumor progression-free survival (LTPFS) and overall survival (OS) after percutaneous radiofrequency ablation (RFA) for solitary colorectal liver metastases (CLM) <3 cm. Both LTPFS and OS were promising after RFA treatment, but patients with tumor-puncturing RFA and a T4 stage primary tumor had poor LTPFS.
Article
Oncology
Florian E. Buisman, Wills F. Filipe, Nancy E. Kemeny, Raja R. Narayan, Rami M. Srouji, Vinod P. Balachandran, Thomas Boerner, Jeffrey A. Drebin, William R. Jarnagin, T. Peter Kingham, Alice C. Wei, Dirk J. Grunhagen, Cornelis Verhoef, Bas Groot Koerkamp, Michael I. D'Angelica
Summary: This study investigated the effectiveness of adjuvant hepatic arterial infusion pump (HAIP) chemotherapy after complete resection or ablation of recurrent colorectal liver metastases and found that adjuvant HAIP is associated with superior hepatic disease-free survival and overall survival.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Lia Assumpcao, Michael Choti, Timothy M. Pawlik, Jean-Francois Gecshwind, Ihab R. Kamel
Article
Gastroenterology & Hepatology
Xavier Dray, Susan K. Redding, Eun J. Shin, Jonathan M. Buscaglia, Samuel A. Giday, Ronald J. Wroblewski, Lia Assumpcao, Devi Mukkai Krishnamurty, Priscilla Magno, Laurie J. Pipitone, Michael R. Marohn, Anthony N. Kalloo, Sergey V. Kantsevoy
GASTROINTESTINAL ENDOSCOPY
(2009)
Article
Gastroenterology & Hepatology
Sergey V. Kantsevoy, Xavier Dray, Eun Ji Shin, Jonathan M. Buscaglia, Priscilla Magno, Lia Assumpcao, Michael R. Marohn, Jay Redan, Samuel A. Giday, Michael A. Schweitzer
GASTROINTESTINAL ENDOSCOPY
(2009)
Article
Gastroenterology & Hepatology
Xavier Dray, Samuel A. Giday, Jonathan M. Buscaglia, Kathleen L. Gabrielson, Sergey V. Kantsevoy, Priscilla Magno, Lia Assumpcao, Eun J. Shin, Susan K. Reddings, Kevin E. Woods, Michael R. Marohn, Anthony N. Kalloo
GASTROINTESTINAL ENDOSCOPY
(2009)
Article
Gastroenterology & Hepatology
Samuel A. Giday, Xavier Dray, Priscilla Magno, Jonathan M. Buscaglia, Eun Ji Shin, Vihar C. Surti, Lia Assumpcao, Michael R. Marohn, Dawn Ruben, Andrew Zhigalin, Laurie J. Pipitone, Sergey V. Kantsevoy
GASTROINTESTINAL ENDOSCOPY
(2010)
Article
Gastroenterology & Hepatology
Lia Assumpcao, John L. Cameron, Christopher L. Wolfgang, Barish Edil, Michael A. Choti, Joseph M. Herman, Jean-Francois Geschwind, Kelvin Hong, Christos Georgiades, Richard D. Schulick, Timothy M. Pawlik
JOURNAL OF GASTROINTESTINAL SURGERY
(2008)
Article
Gastroenterology & Hepatology
Susan Tsai, Michael A. Choti, Lia Assumpcao, John L. Cameron, Ana L. Gleisner, Joseph M. Herman, Frederic Eckhauser, Barish H. Edil, Richard D. Schulick, Christopher L. Wolfgang, Timothy M. Pawlik
JOURNAL OF GASTROINTESTINAL SURGERY
(2010)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mark G. van Vledder, Lia Assumpcao, Sanjay Munireddy, Kartik Sehgal, Emad M. Boctor, Michael A. Choti
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2011)
Article
Surgery
O. R. Meireles, S. V. Kantsevoy, L. R. Assumpcao, P. Magno, X. Dray, S. A. Giday, A. N. Kalloo, E. J. Hanly, M. R. Marohn
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2008)
Article
Gastroenterology & Hepatology
Mark G. van Vledder, Emad M. Boctor, Lia R. Assumpcao, Hassan Rivaz, Pezhman Foroughi, Gregory D. Hager, Ulrike M. Hamper, Timothy M. Pawlik, Michael A. Choti
Article
Oncology
Laura D. Leonard, Laurel Beaty, Madeline Thomas, Christopher Quinn, Kathryn L. Colborn, Thiago B. de Araujo, Robert J. Torphy, Lia R. Assumpcao, Kelly Olino, Christina R. Studts, Salvador Rodriguez Franco, Martin McCarter, Camille Stewart, Ana L. Gleisner
Summary: This study assessed factors associated with the use of completion lymph node dissection (CLND) in patients with surgically resected Stage III melanoma. The study found a decrease in the overall use of CLND during the study period, but there was still high variability, mainly driven by unmeasured contextual effects.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Endocrinology & Metabolism
Ricardo Luiz Costantin Delfim, Lia Roque Assumpcao, Flavia Paiva Proenca Lobo Lopes, Patricia de Fatima dos Santos Teixeira
Summary: The study aimed to determine if classifying hypoechogenicity into three degrees could improve the distinction between benign and malignant nodules and influence the Thyroid Imaging Reporting and Data System (TI-RADS) Category 4. A total of 2,574 nodules were retrospectively assessed, and a subanalysis was performed on solid nodules to evaluate mainly TI-RADS 4 nodules. The results showed that mild hypoechogenicity had a lower association with malignancy compared to moderate and marked hypoechogenicity, and there was no significant association between mildly hypoechoic solid nodules and cancer.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2023)
Article
Surgery
Bruna Brandao de Rezende, Lia Roque Assumpcao, Rui Haddad, Ricardo Mingarini Terra, Ruy Garcia Marques
Summary: This study analyzed the learning curve in robotic thoracic surgery in Brazil and identified factors that can accelerate the learning curve. The presence of a proctor and the use of more advanced technology were found to reduce console time. Further research is needed to understand the factors that impact the learning curve.
JOURNAL OF ROBOTIC SURGERY
(2023)
Article
Urology & Nephrology
Lia Roque Assumpcao, Isadora de Paula Ramos, Gerson Nunes da Cunha, Cid Manso de Mello Vianna, Maria Cristina Araujo Maya, Denizar Vianna Araujo