Article
Public, Environmental & Occupational Health
Salma Ahmed, Vahe Kehyayan, Mariam Abdou, Iheb Bougmiza
Summary: The study found that approximately half of Qatar's adult population has an adequate health literacy level. Among the participants, those with lower levels of education and those who sought medical care within the last week had lower overall health literacy levels.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Xingyue Jin, Kun Zhang, Mireille Twayigira, Xueping Gao, Huiming Xu, Chunxiang Huang, Xuerong Luo, Yanmei Shen
Summary: This study investigated the prevalence of cyberbullying among Chinese college students and identified related factors. The results showed that the prevalence of cyberbullying in the past 12 months was 7.82% among college students. Sex, suicide attempts, depression, and anxiety were found to be independently associated with cyberbullying. Therefore, it is important to address cyberbullying and pay attention to anxiety, depression, and suicidal behaviors among college students to improve their mental health and prevent suicide.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Karar Zunaid Ahsan, Afrin Iqbal, Kanta Jamil, M. Moinuddin Haider, Shusmita Hossain Khan, Nitai Chakraborty, Peter Kim Streatfield
Summary: This study examined the prevalence, awareness, and management of diabetes among adults in Bangladesh in 2017-18 and its association with socioeconomic status. The results showed significant disparities in diabetes prevalence and awareness based on socioeconomic status, but no significant association between socioeconomic status and diabetes control.
Article
Endocrinology & Metabolism
Xiaoqian Dong, Ying Li, Jianfei Xie, Lijun Li, Ziyu Wan, Yue Kang, Yating Luo, Jiangang Wang, Yinglong Duan, Siqing Ding, Andy S. K. Cheng
Summary: This study found that women over 50 and those with mainly manual jobs are more likely to have thyroid nodules, while moderate dietary diversity and normal triglycerides levels can reduce the risk of nodules.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Public, Environmental & Occupational Health
Minjie Zou, Dongwei Guo, Aiming Chen, Charlotte Aimee Young, Yi Li, Danying Zheng, Guangming Jin
Summary: The study revealed that in elderly Chinese populations, females, rural residents, older individuals, and those with lower education levels are at a higher risk of moderate and severe visual impairment and blindness.
JOURNAL OF GLOBAL HEALTH
(2021)
Article
Multidisciplinary Sciences
Sitasnu Dahal, Ram Bilakshan Sah, Surya Raj Niraula, Rajendra Karkee, Avaniendra Chakravartty
Summary: The study in Kathmandu revealed high prevalence of behavioral and metabolic risk factors among adults, with smoking, alcohol consumption, low intake of fruits and vegetables, low physical activity, overweight or obesity, and raised blood pressure being major concerns. Certain demographic factors such as gender, education level, employment status, and ethnicity were found to significantly impact the likelihood of developing these risk factors. Efforts should be made to tailor health promotion interventions specifically to the population at risk in order to reduce the burden of non-communicable diseases.
Article
Biology
Xuling Chang, Resham L. Gurung, Ling Wang, Aizhen Jin, Zheng Li, Renwei Wang, Kenneth B. Beckman, Jennifer Adams-Haduch, Wee Yang Meah, Kar Seng Sim, Weng Khong Lim, Sonia Davila, Patrick Tan, Jing Xian Teo, Khung Keong Yeo, M. Yiamunaa, Sylvia Liu, Su Chi Lim, Jianjun Liu, Rob M. van Dam, Yechiel Friedlander, Woon-Puay Koh, Jian-Min Yuan, Chiea Chuen Khor, Chew-Kiat Heng, Rajkumar Dorajoo
Summary: This study explores the association between low frequency variants and leukocyte telomere length, as well as their potential role in incident cancers and mortalities among East Asians. Three East Asian specific variants at POT1, TERF1, and STN1 loci are found to be linked to leukocyte telomere length and are associated with specific cancers. These findings highlight the importance of ethnicity-specific low frequency variants in telomere length homeostasis and cancer susceptibility.
COMMUNICATIONS BIOLOGY
(2021)
Article
Oncology
Hamed Samavat, Hung N. Luu, Kenneth B. Beckman, Aizhen Jin, Renwei Wang, Woon-Puay Koh, Jian-Min Yuan
Summary: The study revealed that longer telomeres are associated with an increased risk of cancer development, especially for common cancer types like breast, rectal, prostate, pancreatic cancer, and lung adenocarcinoma. Conversely, longer telomeres are linked to a decreased risk of noncancer related death.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Letter
Medicine, General & Internal
Iain Beehuat Tan, Clive Tan, Li Yang Hsu, Yock Young Dan, Andrew Aw, Alex R. Cook, Vernon J. Lee
Summary: This study focuses on the prevalence and outcomes of SARS-CoV-2 infection among migrant workers in Singapore.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Oncology
Alexandre Chan, Kayleen Ports, Patricia Neo, Mothi Babu Ramalingam, Ang Tee Lim, Benedict Tan, Nicolas H. Hart, Raymond J. Chan, Kiley Loh
Summary: This study investigated exercise behavior and factors influencing exercise engagement among cancer survivors at the National Cancer Centre, Singapore (NCCS). The results showed significant reductions in exercise and physical activity among survivors following cancer diagnosis, with treatment side effects being a major barrier. Although most survivors expressed a desire to remain healthy and improve sleep and mental well-being, only a minority received exercise guidance from healthcare professionals.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Medicine, General & Internal
Yu-Xia Zhou, Liang Wang, Ting-Ting Wang, Xiao-Li Qu, Xiao-Qian Zhang
Summary: This study investigates the relationship between HPV infection and reproductive tract infections in the Chinese population, and finds significant differences in HPV infection rates between bacterial vaginosis and fungal vaginitis compared to the control group. Additionally, there are differences in HPV infection rates among different infection types, and some specific HPV genotypes are associated with certain infection types.
Article
Biochemistry & Molecular Biology
Jiahui Lao, Yafei Liu, Yang Yang, Peng Peng, Feifei Ma, Shuang Ji, Yujiao Chen, Fang Tang
Summary: This study analyzed the long-term and seasonal trends of dyslipidemia among the urban Chinese population, revealing significant differences in different genders and age groups. Precautionary measures should be implemented to control the elevated prevalence of dyslipidemia in specific seasons, especially during winter and traditional holidays.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Infectious Diseases
Li Wei Ang, Qi Gao, Lin Cui, Aysha Farwin, Matthias Paul Han Sim Toh, Irving Charles Boudville, Mark I-Cheng Chen, Angela Chow, Raymond Tzer-Pin Lin, Vernon Jian Ming Lee, Yee Sin Leo
Summary: The susceptibility to measles among migrant workers in Singapore was found to be below the herd immunity threshold, indicating the possibility of sporadic outbreaks in susceptible individuals. Seroprevalence surveys can help identify susceptible subgroups for vaccination.
BMC INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Kok Hian Tan, Boon Leng Lim, Zann Foo, Joo Ying Tang, Mabel Sim, Phong Teck Lee, Kok Yong Fong
Summary: This study aimed to examine the prevalence of burnout among different groups of healthcare professionals in Singapore. The results showed that 37.8% of respondents had a high emotional exhaustion score (>27), 29.7% had a high depersonalization score (>10), and 55.3% had a low personal accomplishment score (<=33). There were significant differences in burnout levels among different healthcare professional groups.
ANNALS ACADEMY OF MEDICINE SINGAPORE
(2022)
Article
Psychiatry
Sihong Li, Lintong Song, Mireille Twayigira, Tianqing Fan, Xuerong Luo, Yanmei Shen
Summary: This study investigated the prevalence of eating disorders among 1610 middle school students in Hunan province, China, and found that eating disorders were associated with younger age, non-suicidal self-injury, suicidal ideation, suicide attempts, stress, anxiety, depression, emotional abuse, physical abuse, emotional neglect, physical neglect, social avoidance, and distress related to general social contexts.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Ophthalmology
Sidra Zafar, Kristen A. Staggers, Jie Gao, Yao Liu, Praveen J. Patel, Paul J. Foster, Benjamin J. Frankfort, Michael Abramoff, Charles G. Minard, Alasdair Warwick, Anthony P. Khawaja, Roomasa Channa
Summary: This study examined the relationship between diabetes, glycemic control, and retinal nerve fiber layer thickness. The results showed that higher HbA1c levels and diabetes were associated with thinner superior and inferior pRNFL, indicating the areas most affected by diabetes.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Dolly Shuo-Teh Chang, Yuzhen Jiang, Julia Anne Kim, Shengsong Huang, Beatriz Munoz, Tin Aung, Mingguang He, Paul J. Foster, David Friedman
Summary: This study assessed the long-term impact of laser peripheral iridotomy (LPI) on cataract formation in Chinese primary angle-closure suspect (PACS) patients. The results showed that LPI treatment did not cause significant cataract progression and did not increase the risk of developing clinically meaningful cataract worsening over time.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Medicine, General & Internal
Iris Kleerekooper, Sharon Chua, Paul J. Foster, S. Anand Trip, Gordon T. Plant, Axel Petzold, Praveen Patel
Summary: The study found that current smoking, moderate alcohol intake, and obesity were significantly associated with MS case status. High alcohol intake was associated with thinner mGCIPL in individuals with MS. Smoking was associated with greater mGCIPL thickness in control individuals but not in those with MS.
Article
Endocrinology & Metabolism
Robyn J. Tapp, Christopher G. Owen, Sarah A. Barman, David P. Strachan, Roshan A. Welikala, Paul J. Foster, Peter H. Whincup, Alicja R. Rudnicka
Summary: The study found clear associations between retinal microvascular architecture and cardiometabolic risk factors in patients with diabetes, indicating potential preclinical disease processes and suggesting impaired autoregulation due to hyperglycemia may play a pivotal role in the development of diabetes-related microvascular complications.
Editorial Material
Ophthalmology
Paul J. Foster, Wai Siene Ng, Winifred P. Nolan, Luke Tanner, Gus Gazzard, Alex C. Day, Roshini Sanders, Barny Foot, John F. Salmon, Augusto Azuara-Blanco
Article
Ophthalmology
Alicja R. Rudnicka, Roshan A. Welikala, Sarah A. Barman, Paul J. Foster, Robert Luben, Shabina A. Hayat, Kay-Tee Khaw, Peter H. Whincup, David P. Strachan, Christopher G. Owen
Summary: This study examined the integration of AI-enabled retinal vasculometry in existing risk algorithms for incident stroke, myocardial infarction, and circulatory mortality, finding that the simplified RV model performed equally or better than traditional risk-score models in certain aspects.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Alasdair N. Warwick, Katie Curran, Barbra Hamill, Kelsey Stuart, Anthony P. Khawaja, Paul J. Foster, Andrew J. Lotery, Michael Quinn, Savita Madhusudhan, Konstantinos Balaskas, Tunde Peto
Summary: This study describes the grading methods and baseline characteristics for UK Biobank participants who underwent retinal imaging, and characterizes individuals with retinal features suggestive of age-related macular degeneration, glaucoma, and retinopathy. The results provide important insights into both ocular and systemic health.
Article
Ophthalmology
Matthias M. Mauschitz, Timo Verzijden, Alexander K. Schuster, Hisham Elbaz, Norbert Pfeiffer, Anthony Khawaja, Robert N. Luben, Paul J. Foster, Franziska G. Rauscher, Kerstin Wirkner, Toralf Kirsten, Jost B. Jonas, Mukharram M. Bikbov, Ruth Hogg, Tunde Peto, Audrey Cougnard-Gregoire, Geir Bertelsen, Maja Gran Erke, Fotis Topouzis, Dimitrios A. Giannoulis, Caroline Brandl, Iris M. Heid, Catherine P. Creuzot-Garcher, Pierre-Henry Gabrielle, Hans-Werner Hense, Daniel Pauleikhoff, Patricia Barreto, Rita Coimbra, Stefano Piermarocchi, Vincent Daien, Frank G. Holz, Cecile Delcourt, Robert P. Finger
Summary: This study investigated the association between commonly used systemic medications and prevalent age-related macular degeneration (AMD) in the general population. The results showed that the use of lipid-lowering drugs (LLD) and antidiabetic drugs were associated with a lower prevalence of AMD, supporting the importance of metabolic processes in the development of AMD.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2022)
Correction
Ophthalmology
Alasdair Warwick, Katie Curran, Barbra Hamill, Kelsey Stuart, Anthony P. Khawaja, Paul J. Foster, Andrew J. Lotery, Michael Quinn, Savita Madhusudhan, Konstantinos Balaskas, Tunde Peto
Review
Ophthalmology
Kian M. Madjedi, Kelsey V. Stuart, Sharon Y. L. Chua, Paul J. Foster, Nicholas G. Strouthidis, Robert N. Luben, Alasdair N. Warwick, Jae H. Kang, Janey L. Wiggs, Louis R. Pasquale, Anthony P. Khawaja
Summary: This systematic review summarizes the associations between female reproductive factors and intraocular pressure or open-angle glaucoma. The findings suggest that postmenopausal hormone use is associated with lower intraocular pressure and lower risk of open-angle glaucoma. However, there are no significant associations with parity or age at menarche.
OPHTHALMOLOGY GLAUCOMA
(2022)
Article
Ophthalmology
David S. Friedman, Dolly S. Chang, Yuzhen Jiang, Shengsong Huang, Julia A. Kim, Beatriz Munoz, Tin Aung, Mingguang He, Paul J. Foster
Summary: This study evaluated the risk of AAC after pharmacologic dilation in Chinese individuals classified as having bilateral primary angle-closure suspects (PACSs) and found that the risk was extremely low.
OPHTHALMOLOGY GLAUCOMA
(2022)
Article
Ophthalmology
Chimei Liao, Harry Quigley, Yuzhen Jiang, Shengsong Huang, Wenyong Huang, David Friedman, Paul J. Foster, Mingguang He
Summary: The aim of this study is to evaluate the dynamic changes of iris area and volume with physiologic pupil dilation for the progress of primary angle closure suspects. The results showed that progressors had smaller iris area and volume, and older age, narrower horizontal angle opening distance, flatter iris curvature, and lower loss of iris volume were significantly associated with progression. The change in iris volume is an additional risk factor for identifying eyes more likely to develop angle closure disease.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Medicine, General & Internal
Paul J. Foster, Denize Atan, Anthony Khawaja, Andrew Lotery, Tom MacGillivray, Christopher G. Owen, Praveen J. Patel, Axel Petzold, Alicja Rudnicka, Zihan Sun, Simon Sheard, Naomi Allen
Summary: This article describes the rationale and methodology of eye and vision assessments in the UK Biobank Repeat Imaging study, which aims to provide biomarkers for neuronal and vascular health in cognitive ageing, mild cognitive impairment, and dementia. The study will collect retinal optical coherence tomography (OCT) and colour fundus photographs from a subset of participants to better understand the association between retinal structures, cognitive function, and brain MRI-derived phenotypes.
Article
Medicine, General & Internal
Augusto Azuara-Blanco, John G. Lawrenson, Anthony J. King, Paul J. Foster, Gianni Virgili, Mary Guiney, Winnie Nolan, Anish Jindal, Meenakshi Sharma, Ciaran O'Neill, Christopher R. Cardwell, Mike Clarke
Summary: Angle-closure is a major cause of glaucoma blindness worldwide. This study aims to evaluate the diagnostic performance and cost-effectiveness of two non-contact tests (AS-OCT and gonioscopy) for patients with suspected angle closure.
Article
Ophthalmology
William G. Mitchell, Augusto Azuara-Blanco, Paul J. Foster, Omar Halawa, Jennifer Burr, Craig R. Ramsay, David Cooper, Claire Cochran, John Norrie, David Friedman, Dolly Chang
Summary: This study assessed the baseline ocular parameters predicting long-term intraocular pressure (IOP) control in patients with primary angle closure (PAC) disease after clear lens extraction (CLE) or laser peripheral iridotomy (LPI). The results showed that CLE was more effective in maintaining good IOP control compared to LPI. Non-Chinese ethnicity, higher baseline IOP, and no prior use of glaucoma drops were associated with worse long-term IOP response.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
