Article
Multidisciplinary Sciences
Jorge A. Huete-Perez, Cristiana Cabezas-Robelo, Lucia Paiz-Medina, Carlos A. Hernandez-Alvarez, Carlos Quant-Duran, James H. McKerrow
Summary: The COVID-19 situation in Nicaragua is serious, with government restrictions on testing. 30.35% of healthcare workers were infected, with many asymptomatic and continuing to treat patients. Risk factors for infection include age, sex, and comorbidities, with the highest probability of testing positive among those aged 30-40 years.
Article
Multidisciplinary Sciences
Silvia Stringhini, Maria-Eugenia Zaballa, Nick Pullen, Carlos de Mestral, Javier Perez-Saez, Roxane Dumont, Attilio Picazio, Francesco Pennacchio, Yaron Dibner, Sabine Yerly, Helene Baysson, Nicolas Vuilleumier, Jean-Francois Balavoine, Delphine Bachmann, Didier Trono, Didier Pittet, Francois Chappuis, Omar Kherad, Laurent Kaiser, Andrew S. Azman, Idris Guessous
Summary: The study reveals wide variations in seropositivity rates among workers in different job sectors and occupations in Geneva, Switzerland, indicating higher exposure risk in certain sectors and occupations.
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Mehmet Hakan Taskin, Zafer Yazici, Gerald Barry
Summary: Healthcare workers have a higher risk of being infected with SARS-CoV-2 due to their frequent exposure to infected individuals. This study in Turkey found that approximately 23% of healthcare workers tested positive for anti-SARS-CoV-2 antibodies, and about 30% tested positive for the presence of SARS-CoV-2 RNA without exhibiting typical COVID-19 symptoms. These findings highlight the importance of regular testing for healthcare workers during periods of high community transmission to prevent the entry of the virus into healthcare settings.
Article
Virology
Paola Mariela Saba Villarroel, Maria del Rosario Castro Soto, Veronica Undurraga, Heydi Sanz, Ana Maria Jaldin, Laetitia Ninove, Elif Nurtop, Laura Pezzi, Souand Mohamed Ali, Abdennour Amroun, Morgan Seston, Xavier de Lamballerie
Summary: By the end of January 2021, there was a high SARS-CoV-2 seroprevalence rate among healthcare workers in Cochabamba, Bolivia. The main risk factors identified were having a low-skilled job, living with children, and having been in contact with an infected relative in the household.
Letter
Immunology
Samira Sami, Nga Vuong, Halie Miller, Rachael Priestley, Matthew Payne, Garrett Licata-Portentoso, Jan Drobeniuc, Lyle R. Petersen
Summary: Despite efforts to mitigate the spread of coronavirus in Washington, DC, two outbreaks were identified among office workers. A serologic survey revealed only moderate adherence to workplace mitigation efforts, with infections being linked to activities outside of the workplace. Adherence to safety measures is crucial for a safe return to work during the pandemic.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Immunology
Sombo Fwoloshi, Jonas Z. Hines, Danielle T. Barradas, Samuel Yingst, Mpanji Siwingwa, Lameck Chirwa, James E. Zulu, Dabwitso Banda, Adam Wolkon, Kotey Nikoi, Bob Chirwa, Davies Kampamba, Aaron Shibemba, Suilanji Sivile, Khozya D. Zyambo, Duncan Chanda, Francis Mupeta, Muzala Kapina, Nyambe Sinyange, Nathan Kapata, Paul M. Zulu, Alex Makupe, Aggrey Mweemba, Nyuma Mbewe, Luunga Ziko, Victor Mukonka, Lloyd B. Mulenga, Kennedy Malama, Simon Agolory
Summary: A study conducted in Zambia among healthcare workers in July 2020 found a prevalence rate of 9.3% for SARS-CoV-2, which was similar to the population-based estimate during a period of community transmission. Public health measures such as early establishment of COVID-19 treatment centers and targeted distribution of personal protective equipment may have helped prevent increased transmission among Zambian HCWs.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
S. F. Lumley, D. O'Donnell, N. E. Stoesser, P. C. Matthews, A. Howarth, S. B. Hatch, B. D. Marsden, S. Cox, T. James, F. Warren, L. J. Peck, T. G. Ritter, Z. de Toledo, L. Warren, D. Axten, R. J. Cornall, E. Y. Jones, D. I. Stuart, G. Screaton, D. Ebner, S. Hoosdally, M. Chand, D. W. Crook, A. -M. O'Donnell, C. P. Conlon, K. B. Pouwels, A. S. Walker, T. E. A. Peto, S. Hopkins, T. M. Walker, K. Jeffery, D. W. Eyre
Summary: In a longitudinal study of seropositive and seronegative health care workers undergoing asymptomatic and symptomatic SARS-CoV-2 testing, the presence of anti-spike or anti-nucleocapsid IgG antibodies was associated with a substantially reduced risk of SARS-CoV-2 reinfection in the ensuing 6 months.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Letter
Medicine, General & Internal
Jocelyn Keehner, Lucy E. Horton, Michael A. Pfeffer, Christopher A. Longhurst, Robert T. Schooley, Judith S. Currier, Shira R. Abeles, Francesca J. Torriani
Summary: A study showed that while 71% of healthcare workers tested positive for SARS-CoV-2 within 2 weeks after receiving the vaccine, the percentage decreased after the second dose.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Infectious Diseases
Adeel A. Butt, Hanaa Nafady-Hego, Hiam Chemaitelly, Abdul-Badi Abou-Samra, Abdullatif Al Khal, Peter V. Coyle, Zeina Al Kanaani, Anvar H. Kaleeckal, Ali Nizar Latif, Yousuf Al Masalmani, Roberto Bertollini, Laith J. Abu Raddad
Summary: The risk of developing severe disease or death after breakthrough SARS-CoV-2 infection is higher in older individuals, but lower in those who have been vaccinated. The presence of comorbidities does not affect the severity of disease or death in breakthrough infections.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Toru Suzuki, Kenichi Aizawa, Kenji Shibuya, Shinya Yamanaka, Yuichiro Anzai, Kiyoshi Kurokawa, Ryozo Nagai
Summary: This cross-sectional study examines the prevalence of asymptomatic SARS-CoV-2 infection in Japan and finds a lower infection rate compared to reported levels in other parts of the world.
Article
Multidisciplinary Sciences
Ryuta Uraki, Maki Kiso, Shun Iida, Masaki Imai, Emi Takashita, Makoto Kuroda, Peter J. Halfmann, Samantha Loeber, Tadashi Maemura, Seiya Yamayoshi, Seiichiro Fujisaki, Zhongde Wang, Mutsumi Ito, Michiko Ujie, Kiyoko Iwatsuki-Horimoto, Yuri Furusawa, Ryan Wright, Zhenlu Chong, Seiya Ozono, Atsuhiro Yasuhara, Hiroshi Ueki, Yuko Sakai-Tagawa, Rong Li, Yanan Liu, Deanna Larson, Michiko Koga, Takeya Tsutsumi, Eisuke Adachi, Makoto Saito, Shinya Yamamoto, Masao Hagihara, Keiko Mitamura, Tetsuro Sato, Masayuki Hojo, Shin-ichiro Hattori, Kenji Maeda, Riccardo Valdez, Moe Okuda, Jurika Murakami, Calvin Duong, Sucheta Godbole, Daniel C. Douek, Ken Maeda, Shinji Watanabe, Aubree Gordon, Norio Ohmagari, Hiroshi Yotsuyanagi, Michael S. Diamond, Hideki Hasegawa, Hiroaki Mitsuya, Tadaki Suzuki, Yoshihiro Kawaoka
Summary: The replicative ability and pathogenicity of Omicron BA.2 variant is similar to that of BA.1 in rodents, but it shows less pathogenicity compared to early SARS-CoV-2 strains. There is a marked reduction in the neutralizing activity of plasma from individuals who had recovered from COVID-19 and vaccine recipients against BA.2 variant.
Article
Microbiology
Gregorio P. Milani, Mario G. Bianchetti, Giuseppe Togni, Andreas W. Schoenenberger, Franco Muggli
Summary: The study found that healthcare workers not primarily caring for SARS-CoV-2 patients are seven times more likely to be infected with the virus compared to the general population. This highlights the need for efforts to effectively protect all healthcare personnel.
Article
Virology
Christine C. Johnson, Chad M. Coleman, Alexandra R. Sitarik, Joyce E. Leon, Robert J. Tibbetts, Bernard C. Cook, Bruce K. Muma, Allison J. Weinmann, Linoj P. Samuel
Summary: This study found that the period prevalence of PCR positivity to SARS-CoV-2 and IgG seroprevalence was unexpectedly low among asymptomatic healthcare workers after the peak of COVID-19 admissions, suggesting that routine screening tests may not be very effective in this population.
JOURNAL OF CLINICAL VIROLOGY
(2021)
Article
Immunology
Johanna Erber, Verena Kappler, Bernhard Haller, Hrvoje Mijocevic, Ana Galhoz, Clarissa Prazeres da Costa, Friedemann Gebhardt, Natalia Graf, Dieter Hoffmann, Markus Thaler, Elke Lorenz, Hedwig Roggendorf, Florian Kohlmayer, Andreas Henkel, Michael P. Menden, Jurgen Ruland, Christoph D. Spinner, Ulrike Protzer, Percy Knolle, Paul Lingor
Summary: This study investigated the prevalence of SARS-CoV-2 infection in hospital staff in Munich, Germany and found that staff engaged in direct patient care had a similar probability of being seropositive as non-patient-facing staff. Increased risk of infection was observed in staff who had interactions with infected coworkers or private contacts, as well as those who had exposure to COVID-19 patients without appropriate personal protective equipment. The study also identified that the infection hotspots for SARS-CoV-2-positive staff and patients only partially overlapped.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Immunology
Md. Imam Hossain, Protim Sarker, Rubhana Raqib, Md Ziaur Rahman, Rezaul Hasan, Chloe K. K. Svezia, Mahbubur Rahman, Nuhu Amin
Summary: In response to the COVID-19 pandemic, host countries have imposed entry requirements, including seroconversion proof, for migrant workers. This study assessed antibody levels among Bangladeshi migrant workers vaccinated with different COVID-19 vaccines. The results showed that all participants had antibodies to the S-protein, and a high percentage also had antibodies to the N-protein.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Infectious Diseases
Zheng Jie Marc Ho, Gunalan Vithia, Ching Ging Ng, Sebastian Maurer-Stroh, Clive M. Tan, Jimmy Loh, Tzer Pin Raymond Lin, Jian Ming Vernon Lee
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2015)
Meeting Abstract
Health Care Sciences & Services
Clive Tan, Rasul Baghirov, Jason Yap, Vivian Lin
INTERNATIONAL JOURNAL OF INTEGRATED CARE
(2017)
Article
Public, Environmental & Occupational Health
Clive M. Tan, Ian Wern Tan, Wai Leong Kok, Melvin C. Lee, Vernon J. Lee
Article
Health Care Sciences & Services
Nan-Guang Tan, Lily Wei-Yun Yang, Mark Zhong-Wei Tan, Jeremiah Chng, Marcus Hong-Tat Tan, Clive Tan
Summary: This pilot study demonstrates the safety and effectiveness of on-premises telemedicine for primary health care services, with high user satisfaction.
JOURNAL OF TELEMEDICINE AND TELECARE
(2022)
Article
Medicine, General & Internal
Clive Tan, Lavinia Lin, Mervyn Lim, Seeu Kun Ong, Mee-Lian Wong, Jeong Kyu Lee
Letter
Medicine, General & Internal
Si Jack Chong, Sreemanee Raaj Dorajoo, Seng Bin Ang, Iain Beehuat Tan, Clive Tan, Kok Pun Foong, Jui Sheng Choo, Li Yang Hsu, Weilong Yeo, Eti Bhasker, Chun Shan Goh, Saihah Ismadi, Cherng Yeu Neo, Michael Tack Keong Wong
ANNALS ACADEMY OF MEDICINE SINGAPORE
(2021)
Article
Multidisciplinary Sciences
Rachael Pung, Bernard Lin, Sebastian Maurer-Stroh, Fernanda L. Sirota, Tze Minn Mak, Sophie Octavia, Junxiong Pang, Iain Beehuat Tan, Clive Tan, Biauw Chi Ong, Alex R. Cook, Vernon J. Lee
Summary: The study found that asymptomatic cases and symptomatic cases who did not seek medical attention were major drivers of the dormitory outbreak. Each infected resident spread to an average of 4.4 others, and the outbreak attack rate could be reduced by 10% under modified dormitory housing conditions.
SCIENTIFIC REPORTS
(2021)
Letter
Medicine, General & Internal
Jeremy Teoh, M. T. Wahab, Joshua T. C. Tan, Luo-Kai Wang, Clive Tan
ANNALS ACADEMY OF MEDICINE SINGAPORE
(2022)
Article
Immunology
Muhammad Taufeeq Wahab, Rayner Kay Jin Tan, Alex R. Cook, Kiesha Prem
Summary: Globally, gender-neutral HPV vaccination programmes are becoming popular. The cost-effectiveness of including adolescent boys in Singapore's school-based HPV vaccination programme was assessed. A model was used to calculate the cost and QALY for vaccinating 13-year-olds with the HPV vaccine. The findings suggest that a gender-neutral vaccination programme with the bivalent vaccine is cost-effective at a 1.5% discount rate.
Article
Medicine, General & Internal
Joshua T. C. Tan, Clive Tan, Jeremy Teoh, M. T. Wahab, Guan Zhong Tan, Reon Yew Zhou Chin, Anne Lee, Adeliza Mutalib, Poh Lian Lim
Summary: A vaccination exercise involving Asian military personnel found that common minor adverse reactions to mRNA COVID-19 vaccines included fever/chills, body aches, and injection site pain. Younger individuals experienced minor adverse reactions more frequently, while rare cases of anaphylaxis, Bell's palsy, and myocarditis/pericarditis were observed. The study supports the favorable safety profile of mRNA COVID-19 vaccines and may provide guidance for decisions on booster doses.
ANNALS ACADEMY OF MEDICINE SINGAPORE
(2021)
Article
Psychology, Clinical
Jeong Kyu Lee, Lavinia Lin, Mervyn Jun Rui Lim, Yvette Van der Eijk, Kee Seng Chia, Clive Tan
JOURNAL OF PSYCHOACTIVE DRUGS
(2020)
Article
Medicine, General & Internal
C. M. Tan, V. J. Lee, G. H. Chang, H. X. Ang, B. Seet
SINGAPORE MEDICAL JOURNAL
(2012)
